Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Rui Lan Huang"'
NKX6-1 mediates cancer stem-like properties and regulates sonic hedgehog signaling in leiomyosarcoma
Autor:
Po-Hsuan Su, Rui-Lan Huang, Hung-Cheng Lai, Lin-Yu Chen, Yu-Chun Weng, Chih-Chien Wang, Chia-Chun Wu
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-15 (2021)
Abstract Background Leiomyosarcoma (LMS), the most common soft tissue sarcoma, exhibits heterogeneous and complex genetic karyotypes with severe chromosomal instability and rearrangement and poor prognosis. Methods Clinical variables associated with
Externí odkaz:
https://doaj.org/article/6ad8d3cb550441c1afe6a070e5904090
Autor:
Yu-Chien Lin, Kuo-Chang Wen, Pi-Lin Sung, Yu-Ting Chou, Phui-Ly Liew, Lin-Yu Chen, Rui-Lan Huang, Hung-Cheng Lai, Lu-Te Chang
Publikováno v:
Journal of Ovarian Research, Vol 13, Iss 1, Pp 1-6 (2020)
Abstract Background Patients with ovarian clear cell carcinoma (OCCC) have a poor prognosis because they show low sensitivity to platinum-based chemotherapy. New treatments for refractory OCCC are urgently needed. Case presentation We present a patie
Externí odkaz:
https://doaj.org/article/3447f8789881452381b0e1e0cd7965cb
Autor:
Chien-Wen Chen, Heng-Cheng Chang, Tzu-Fei Huang, Chi-Chun Liao, Rui-Lan Huang, Hung-Cheng Lai
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 58, Iss 4, Pp 514-519 (2019)
Objective: To share our experience of transition from multiport to single-site robotic surgery for benign gynecological conditions as well as to assess the selection criteria of candidates for robotic single-site supracervical hysterectomy (RSSH). Ma
Externí odkaz:
https://doaj.org/article/72771ffaee7c4e10bf3b63c42a358305
Autor:
Maggie K. S. Tang, Patrick Y. K. Yue, Philip P. Ip, Rui-Lan Huang, Hung-Cheng Lai, Annie N. Y. Cheung, Ka Yu Tse, Hextan Y. S. Ngan, Alice S. T. Wong
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
A soluble form E-cadherin is highly expressed in ovarian cancer. Here, the authors show that soluble E-cadherin is released by ovarian cancer cells packaged in exosomes and promotes tumor angiogenesis through β-catenin and NFkB signaling activation.
Externí odkaz:
https://doaj.org/article/599dda1639f747589df0acf5f4d2b966
Autor:
Hung-Cheng Lai, Mu-Hsien Yu, Tim Huang, Kenneth P. Nephew, Cheng-Chang Chang, Chi-Kuan Chen, Huey-Kang Sytwu, Michael W.Y. Chan, Rui-Lan Huang, Curt Balch, Yu-Chi Wang, Ya-Wen Lin, Yi-Te Yo
PDF file, 27KB, Differential stem cell signaling between CP70 and CP70sps were compared using an RT-PCR pathway-focused arrays (Stem signaling/Wnt signaling). Red indicates gene upregulation while green indicates gene downregulation, in CP70sps cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42da11399d750ba1b92c6fc2dcbbd57b
https://doi.org/10.1158/1535-7163.22497327.v1
https://doi.org/10.1158/1535-7163.22497327.v1
Autor:
Hung-Cheng Lai, Mu-Hsien Yu, Tim Huang, Kenneth P. Nephew, Cheng-Chang Chang, Chi-Kuan Chen, Huey-Kang Sytwu, Michael W.Y. Chan, Rui-Lan Huang, Curt Balch, Yu-Chi Wang, Ya-Wen Lin, Yi-Te Yo
PDF file, 1369KB, A, pretreatment of cells with the ABCG2 inhibitor GF120918 essentially eliminated the SP fraction of CP70 ovarian cancer cells (right panel). B, ovarian cancer CP70 SP spheroid-forming cells ("CP70sps cells"). CP70 SP cells were cul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1fd2527d103657ea3b79299fb4a011
https://doi.org/10.1158/1535-7163.22497339.v1
https://doi.org/10.1158/1535-7163.22497339.v1
Autor:
Hung-Cheng Lai, Mu-Hsien Yu, Tim Huang, Kenneth P. Nephew, Cheng-Chang Chang, Chi-Kuan Chen, Huey-Kang Sytwu, Michael W.Y. Chan, Rui-Lan Huang, Curt Balch, Yu-Chi Wang, Ya-Wen Lin, Yi-Te Yo
PDF file, 2736KB, Niclosamide treatment (10mg/kg/daily) was given intraperitoneally every week one day after OTICs inoculation in NOD/SCID mice. Furthermore, Body weights remained constant during niclosamide treatment demonstrating a lack of systemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3b337816d1b77b1dab5b57a29ba3ac
https://doi.org/10.1158/1535-7163.22497336
https://doi.org/10.1158/1535-7163.22497336
Autor:
Hung-Cheng Lai, Mu-Hsien Yu, Tim Huang, Kenneth P. Nephew, Cheng-Chang Chang, Chi-Kuan Chen, Huey-Kang Sytwu, Michael W.Y. Chan, Rui-Lan Huang, Curt Balch, Yu-Chi Wang, Ya-Wen Lin, Yi-Te Yo
A recent hypothesis for cancer chemoresistance posits that cytotoxic survival of a subpopulation of tumor progenitors drives the propagation of recurrent disease, underscoring the need for new therapeutics that target such primitive cells. To discove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b1e78491538488d81bd40ca16b29d1
https://doi.org/10.1158/1535-7163.c.6535587
https://doi.org/10.1158/1535-7163.c.6535587
Autor:
Hung-Cheng Lai, Mu-Hsien Yu, Tim Huang, Kenneth P. Nephew, Cheng-Chang Chang, Chi-Kuan Chen, Huey-Kang Sytwu, Michael W.Y. Chan, Rui-Lan Huang, Curt Balch, Yu-Chi Wang, Ya-Wen Lin, Yi-Te Yo
PDF file, 4382KB, One day after inoculation of 1�106 CP70 cells in NOD/SCID mice, niclosamide (10mg/kg/day) was administered intraperitoneally for three weeks, then twice a week for 2 weeks. After 9 weeks, mice were sacrificed, and tumor size/incid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7ca7fed7cf8b4fcd0564226f25b1af
https://doi.org/10.1158/1535-7163.22497333
https://doi.org/10.1158/1535-7163.22497333
Autor:
Hung-Cheng Lai, Mu-Hsien Yu, Tim Huang, Kenneth P. Nephew, Cheng-Chang Chang, Chi-Kuan Chen, Huey-Kang Sytwu, Michael W.Y. Chan, Rui-Lan Huang, Curt Balch, Yu-Chi Wang, Ya-Wen Lin, Yi-Te Yo
PDF file, 82KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd8fcd2b65d283034998faff12714bc
https://doi.org/10.1158/1535-7163.22497330.v1
https://doi.org/10.1158/1535-7163.22497330.v1