Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Rui Benedito"'
Autor:
Roshana Thambyrajah, Maria Maqueda, Wen Hao Neo, Kathleen Imbach, Yolanda Guillén, Daniela Grases, Zaki Fadlullah, Stefano Gambera, Francesca Matteini, Xiaonan Wang, Fernando J. Calero-Nieto, Manel Esteller, Maria Carolina Florian, Eduard Porta, Rui Benedito, Berthold Göttgens, Georges Lacaud, Lluis Espinosa, Anna Bigas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Hematopoietic stem cells (HSCs) develop from the hemogenic endothelium (HE) in the aorta- gonads-and mesonephros (AGM) region and reside within Intra-aortic hematopoietic clusters (IAHC) along with hematopoietic progenitors (HPC). The signal
Externí odkaz:
https://doaj.org/article/89ff244b2ed24e0cb8b752459be716ea
Autor:
Samuel Pontes-Quero, Macarena Fernández-Chacón, Wen Luo, Federica Francesca Lunella, Verónica Casquero-Garcia, Irene Garcia-Gonzalez, Ana Hermoso, Susana F. Rocha, Mayank Bansal, Rui Benedito
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
High mitogenic stimuli have been suggested to promote endothelial cell proliferation and sprouting during angiogenesis. Here Pontes-Quero et al., by interfering with levels of VEGF and Notch signalling in single endothelial cells in vivo, find that h
Externí odkaz:
https://doaj.org/article/bdd178fe974e4a4f962429db249693cf
Autor:
Macarena Fernández-Chacón, Verónica Casquero-García, Wen Luo, Federica Francesca Lunella, Susana Ferreira Rocha, Sergio Del Olmo-Cabrera, Rui Benedito
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The Cre-Lox system allows high spatiotemporal control of genetic modifications. Here the authors present iSuRe-Cre that significantly increases Cre activity in reporter expressing cells, which ultimately increases the efficiency and reliability of Cr
Externí odkaz:
https://doaj.org/article/e50289266aca4746824f4bb0ef51b537
Autor:
María Crespo, Barbara Gonzalez-Teran, Ivana Nikolic, Alfonso Mora, Cintia Folgueira, Elena Rodríguez, Luis Leiva-Vega, Aránzazu Pintor-Chocano, Macarena Fernández-Chacón, Irene Ruiz-Garrido, Beatriz Cicuéndez, Antonia Tomás-Loba, Noelia A-Gonzalez, Ainoa Caballero-Molano, Daniel Beiroa, Lourdes Hernández-Cosido, Jorge L Torres, Norman J Kennedy, Roger J Davis, Rui Benedito, Miguel Marcos, Ruben Nogueiras, Andrés Hidalgo, Nuria Matesanz, Magdalena Leiva, Guadalupe Sabio
Publikováno v:
eLife, Vol 9 (2020)
Liver metabolism follows diurnal fluctuations through the modulation of molecular clock genes. Disruption of this molecular clock can result in metabolic disease but its potential regulation by immune cells remains unexplored. Here, we demonstrated t
Externí odkaz:
https://doaj.org/article/68531b33dacf4efb84a24e972b0693bf
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Progress in biomedical science is tightly associated with the improvement of methods and genetic tools to manipulate and analyze gene function in mice, the most widely used model organism in biomedical research. The joint effort of numerous individua
Externí odkaz:
https://doaj.org/article/0189d6b2cc3b4dd580a0cd2f32420ae2
Autor:
Frank Bicker, Verica Vasic, Guilherme Horta, Felipe Ortega, Hendrik Nolte, Atria Kavyanifar, Stefanie Keller, Nevenka Dudvarski Stankovic, Patrick N. Harter, Rui Benedito, Beat Lutz, Tobias Bäuerle, Jens Hartwig, Jan Baumgart, Marcus Krüger, Konstantin Radyushkin, Lavinia Alberi, Benedikt Berninger, Mirko H. H. Schmidt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
The vascular stem cell niche regulates the proliferation and differentiation of neural stem cells (NSCs) in the adult subventricular zone. Here the authors identify EGFL7 as a neurovascular regulator of NSCsin vivo; EGFL7-knockout mice show reduced n
Externí odkaz:
https://doaj.org/article/893b1f84a39b4db9ad2ea276781e4fdb
Autor:
Sergio Menchero, Isabel Rollan, Antonio Lopez-Izquierdo, Maria Jose Andreu, Julio Sainz de Aja, Minjung Kang, Javier Adan, Rui Benedito, Teresa Rayon, Anna-Katerina Hadjantonakis, Miguel Manzanares
Publikováno v:
eLife, Vol 8 (2019)
The Notch signalling pathway plays fundamental roles in diverse developmental processes in metazoans, where it is important in driving cell fate and directing differentiation of various cell types. However, we still have limited knowledge about the r
Externí odkaz:
https://doaj.org/article/9f28b9ee1cf9494985b8f517ca1a4e2a
Autor:
Samuel Pontes-Quero, Macarena Fernández-Chacón, Wen Luo, Federica Francesca Lunella, Verónica Casquero-Garcia, Irene Garcia-Gonzalez, Ana Hermoso, Susana F. Rocha, Mayank Bansal, Rui Benedito
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained errors in Fig. 8. In panel a, the labels ‘VEGF’, ‘Notch’, ‘p21’, and ‘P-ERK’ were inadvertently omitted. This has been corrected in the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/af843f14dfae4edc80c5f1acc1ae6848
Autor:
Macarena Fernández-Chacón, Severin Mühleder, Alvaro Regano, Lourdes Garcia-Ortega, Susana F. Rocha, Carlos Torroja, Maria S. Sanchez-Muñoz, Mariya Lytvyn, Verónica Casquero-Garcia, Macarena De Andrés-Laguillo, Lars Muhl, Michael M. Orlich, Konstantin Gaengel, Emilio Camafeita, Jesús Vázquez, Alberto Benguría, M. Luisa Iruela-Arispe, Ana Dopazo, Fátima Sánchez-Cabo, Hannah Carter, Rui Benedito
Publikováno v:
Nature Cardiovascular Research.
Research in R.B.’s laboratory was supported by the European Research Council Starting Grant AngioGenesHD (638028) and Consolidator Grant AngioUnrestUHD (101001814), the CNIC Intramural Grant Program Severo Ochoa (11-2016-IGP-SEV-2015-0505), the Min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487eb8ed8636b357f26a00a5c5f9ad3b
https://doi.org/10.1038/s44161-023-00272-4
https://doi.org/10.1038/s44161-023-00272-4
Autor:
Irene Garcia-Gonzalez, Stefano Gambera, Alvaro Regano, Susana F. Rocha, Lourdes Garcia-Ortega, Mariya Lytvyn, Maria S. Sanchez-Muñoz, Aroa Garcia-Cabero, Ivana Zagorac, Wen Luo, Macarena Fernández-Chacón, Verónica Casquero-Garcia, Federica Francesca Lunella, Rui Benedito
In order to understand gene function, cells mutated for a gene need to be compared with normal cells. In most biomedical studies this comparative analysis is carried out with cells present in different animals and therefore not experiencing the same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::923e06ee404a654e02ff040d6a2d814b
https://doi.org/10.1101/2023.05.09.540000
https://doi.org/10.1101/2023.05.09.540000
