Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Rui André Saraiva, Raposo"'
Autor:
Andrew Wiznia, Martin Bortlik, Douglas F. Nixon, Rui André Saraiva Raposo, Phillip M. Brailey, Dennis C Copertino, Miguel de Mulder Rougvie, Greta A. Beckerle, Christopher E. Ormsby, Michael G. Rosenberg
Publikováno v:
Pediatric Infectious Disease Journal. 40:144-146
INTRODUCTION Around 1.7 million children are estimated to live with HIV-1 worldwide, and about 160,000 infants are newly infected every year. Since adaptive immunity takes time to mature and develop in infants, and maternal antibodies provide limited
Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection.
Autor:
Stephane Champiat, Rui André Saraiva Raposo, Nicholas J Maness, John L Lehman, Sean E Purtell, Aaron M Hasenkrug, Jacob C Miller, Hansi Dean, Wayne C Koff, Marisa Ailin Hong, Jeffrey N Martin, Steven G Deeks, Gerald E Spotts, Christopher D Pilcher, Fredrick M Hecht, Esper G Kallas, Keith E Garrison, Douglas F Nixon
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39311 (2012)
Translational errors can result in bypassing of the main viral protein reading frames and the production of alternate reading frame (ARF) or cryptic peptides. Within HIV, there are many such ARFs in both sense and the antisense directions of transcri
Externí odkaz:
https://doaj.org/article/fe9aa30c9e5d4ac59e0c53a7aff44b99
Autor:
Rui André Saraiva Raposo, Benjamin C. Greenspun, Dominic Paquin-Proulx, Shannon M Kitchen, Douglas F. Nixon, Leon Grayfer
Publikováno v:
Cytokine. 111:272-277
The establishment of latent HIV-1 reservoirs in terminally differentiated cells represents a major impediment to the success of antiretroviral therapies. Notably, macrophages (Mϕs) are susceptible to HIV-1 infection and recent evidence suggests that
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18690 (2011)
Human macrophages (Mφ) express low levels of CD4 glycoprotein, which is constitutively recycled, and 40-50% of its localization is intracellular at steady-state. Although CD4-interacting proteins in lymphoid cells are well characterised, little is k
Externí odkaz:
https://doaj.org/article/ad653c85b8e743e185c87578635e4f52
Autor:
Richard Apps, Rui André Saraiva Raposo, Miguel de Mulder Rougvie, Talia M. Mota, R. Brad Jones, Douglas F. Nixon, Nathaniel D. Bachtel, Greta A. Beckerle
Publikováno v:
AIDS research and human retroviruses. 35(1)
Much has been learnt from the functions of host restriction factors during acute and chronic HIV-1 infection, but far less is known about their role in HIV-1-infected individuals in which viral load is stably suppressed with antiretroviral therapy (A
Autor:
Robert M. Grant, Sara J. Holditch, Rex G. Cheng, Megha Mehrotra, Brian I. Shaw, Vanessa McMahan, Esper G. Kallas, Douglas F. Nixon, Peter J. Kuebler, Emily M. Eriksson, Leandro F. Tarosso, Jeffrey M. Milush, David V. Glidden, Rui André Saraiva Raposo, Kaitlyn S. Leadabrand, Vanessa A. York, J. Jeff McConnell, Stephen Shiboski
Publikováno v:
Proceedings of the National Academy of Sciences. 112:8379-8384
HIV-1-specific T-cell responses in exposed seronegative subjects suggest that a viral breach of the exposure site is more common than current transmission rates would suggest and that host immunity can extinguish subsequent infection foci. The Preexp
Autor:
Jashin J. Wu, Wilson Liao, Satish K. Pillai, Sarah T. Arron, Mona Malakouti, Mohamed Abdel-Mohsen, Gabrielle Brown, Rui André Saraiva Raposo, Kaitlyn S. Leadabrand, Peter J. Kuebler, Rashmi Gupta, Maya Debbaneh, Michelle Dimon, W. Jiang, Vanessa A. York, Douglas F. Nixon
Publikováno v:
Journal of the European Academy of Dermatology and Venereology : JEADV, vol 29, iss 10
BackgroundPsoriasis patients have relatively infrequent cutaneous viral infections compared to atopic dermatitis patients. Increased expression of four antiviral proteins (MX1, BST2, ISG15 and OAS2) has been reported in psoriatic skin and genetic stu
Autor:
Jashin J, Wu, Kathleen E, Gilbert, Michael, Batech, Iviensan F, Manalo, William J, Towner, Rui André Saraiva, Raposo, Douglas F, Nixon, Wilson, Liao
Publikováno v:
Journal of drugs in dermatology : JDD. 16(4)
pBACKGROUND: HIV-associated psoriasis is well-documented. Genetic, cellular, and cytokine profiles have been used as evidence to suggest psoriasis activates antiviral pathways. There has been a lack of epidemiologic evidence investigating whether pso
Autor:
Wes Yonemoto, Karen Trang, Margaret M. Lowe, Elisabeth R. Krow-Lucal, Vinicius D. Cabido, Devi SenGupta, Rui André Saraiva Raposo, Joseph M. McCune
Publikováno v:
Viral immunology. 30(3)
Among untreated HIV-infected pregnant women, the frequency of mother-to-child transmission of HIV is low (5-10%), with most infections occurring at or after birth. Given findings that fetal and adult monocytes are distinct from one another in terms o
Autor:
Phillip M. Brailey, Richard B. Jones, Rui André Saraiva Raposo, Szu-Han Huang, Paul M. Zdinak, Vinicius D. Cabido, Dominic Paquin-Proulx, Greta A. Beckerle, Miguel de Mulder Rougvie, Allison S. Thomas, Douglas F. Nixon
Publikováno v:
JCI Insight. 2
HIV-1 persistence in latent reservoirs during antiretroviral therapy (ART) is the main obstacle to virus eradication. To date, there is no marker that adequately identifies latently infected CD4+ T cells in vivo. Using a well-established ex vivo mode