Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Rui A. S. Lapa"'
Publikováno v:
Process Biochemistry. 108:121-128
Understanding the potential of ionic liquids in biocatalysis is both useful and difficult. The unique properties of ionic liquids, such as their tunability, allow for the medium to be adjusted to the reaction, thereby supporting both substrate solubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f92fe5ce0f431dc566b847f86328a4fe
https://doi.org/10.1016/j.procbio.2021.06.003
https://doi.org/10.1016/j.procbio.2021.06.003
Publikováno v:
Current Drug Metabolism. 22:150-162
Background:: Vancomycin has been in clinical use for nearly 50 years and remains the first-line treatment option for Gram-positive infections, including methicillin-resistant Staphylococcus aureus (MRSA). There are multiple strategies to monitor ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa216b41d3dde52b643d8b84a6c02f89
https://doi.org/10.2174/1389200221999210101232417
https://doi.org/10.2174/1389200221999210101232417
Publikováno v:
Life, Vol 11, Iss 1130, p 1130 (2021)
Life; Volume 11; Issue 11; Pages: 1130
Life
Life; Volume 11; Issue 11; Pages: 1130
Life
The importance of closely observing patients receiving antibiotic therapy, performing therapeutic drug monitoring (TDM), and regularly adjusting dosing regimens has been extensively demonstrated. Additionally, antibiotic resistance is a contemporary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e468a831d3d4ecf4dcd1ba4439084e7
https://www.mdpi.com/2075-1729/11/11/1130
https://www.mdpi.com/2075-1729/11/11/1130
Autor:
Nuno Vale, Arto Urtti, Joana Santos, Rui A. S. Lapa, Abigail Ferreira, Cristiana V. Correia, Marjo Yliperttula
Publikováno v:
Molecules
Volume 26
Issue 14
Molecules, Vol 26, Iss 4257, p 4257 (2021)
Volume 26
Issue 14
Molecules, Vol 26, Iss 4257, p 4257 (2021)
Pharmacokinetic (PK) studies improve the design of dosing regimens in preclinical and clinical settings. In complex diseases like cancer, single-agent approaches are often insufficient for an effective treatment, and drug combination therapies can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1dfe7028d67a3c59462c3b8606e98e3
Publikováno v:
ADMET and DMPK (2020)
ADMET and DMPK
Volume 9
Issue 1
ADMET and DMPK
Volume 9
Issue 1
Cancer is one of the most alarming diseases due to its high mortality and still increasing incidence rate. Currently available treatments for this condition present several shortcomings and new options are continuously being developed and evaluated,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9dbc7a0a5eb1e0eaff2c8a4710d26f
https://pubmed.ncbi.nlm.nih.gov/35310327
https://pubmed.ncbi.nlm.nih.gov/35310327
Publikováno v:
Processes, Vol 9, Iss 2087, p 2087 (2021)
Pharmacokinetics (PK) is a branch of pharmacology present and of vital importance for the research and development (R&D) of new drugs, post-market monitoring, and continued optimizations in clinical contexts. Ultimately, pharmacokinetics can contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc088fcb197b6cf35fe56452090d946
https://doi.org/10.3390/pr9112087
https://doi.org/10.3390/pr9112087
Publikováno v:
Biomolecules
Volume 9
Issue 11
Biomolecules, Vol 9, Iss 11, p 693 (2019)
Volume 9
Issue 11
Biomolecules, Vol 9, Iss 11, p 693 (2019)
Gemcitabine is an anticancer drug used to treat a wide range of solid tumors and is a first line treatment for pancreatic cancer. Our group has previously developed novel conjugates of gemcitabine with cell-penetrating peptides (CPP), and here we rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bb62211a0bba184db08893ba533053
http://europepmc.org/articles/PMC6921036
http://europepmc.org/articles/PMC6921036
Publikováno v:
Journal of Hazardous Materials. 284:136-142
A fully automated Vibrio fischeri methodology based on sequential injection analysis (SIA) has been developed. The methodology was based on the aspiration of 75 μL of bacteria and 50 μL of inhibitor followed by measurement of the luminescence of ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afe813f3279c1264769f03769c2222b
https://doi.org/10.1016/j.jhazmat.2014.10.049
https://doi.org/10.1016/j.jhazmat.2014.10.049
Publikováno v:
Analytical and Bioanalytical Chemistry. 397:381-388
A simple, low-cost process to integrate complementary metal oxide semiconductor array detectors (CMOSAD) for chemiluminescence is presented, evaluated, and applied to the determination of nitrite in ground water samples. CMOS arrays of different bran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1be0bd78a215b13ca2ddff164c135e
https://doi.org/10.1007/s00216-010-3518-x
https://doi.org/10.1007/s00216-010-3518-x
Publikováno v:
Microchimica Acta. 166:189-195
The development of micro-flow devices by direct-milling on poly(methyl methacrylate) (PMMA) substrates and incorporating the optic detector into the same structure is presented, evaluated and applied to the determination of chlorhexidine. Hydrodynami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c185257852076a8423ac59ff2aecbbec
https://doi.org/10.1007/s00604-009-0207-6
https://doi.org/10.1007/s00604-009-0207-6