Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Rui‑Juan Gao"'
Autor:
Rui-Juan Gao, Nigala Aikeremu, Nan Cao, Chong Chen, Ke-Tao Ma, Li Li, Ai-Mei Zhang, Jun-Qiang Si
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Pulmonary arterial hypertension (PAH) is a worldwide challenging disease characterized by progressive elevation of pulmonary artery pressure. The proliferation, migration and phenotypic transformation of pulmonary smooth muscle ce
Externí odkaz:
https://doaj.org/article/3fc2a4ec804946f8a797b6f91518957e
Autor:
Si Su, Meng-Yu Cui, Li-Li Xing, Rui-Juan Gao, Lan Mu, Mei Hong, Qi-Qi Guo, Hong Ren, Jing-Feng Yu, Xiao-Yan Si, Mutu Eerde
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 12, p e0012706 (2024)
BackgroundTicks are widely distributed throughout China and are the second most prevalent pathogen vectors in the world, following only mosquitoes. Tick bites can lead to Lyme disease, forest encephalitis, and other illnesses that may result in death
Externí odkaz:
https://doaj.org/article/86d9ca528aa24a478ce0f7e5698199c3
Autor:
Dan-dan Zhou, Xiao-tian Zhai, Lan-wen Zhang, Zi-hui Xie, Ying Wang, Yong-su Zhen, Rui-juan Gao, Qing-fang Miao
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-16 (2024)
Abstract Trophoblast cell surface antigen 2 (Trop2) is considered to be an attractive therapeutic target in cancer treatments. We previously generated a new humanized anti-Trop2 antibody named hIMB1636, and designated it as an ideal targeting carrier
Externí odkaz:
https://doaj.org/article/866f250ded27490cb3efdaeecc640bc5
Autor:
Jingrong Zhang, Li Li, Ke-Tao Ma, Shi-Yu Deng, Liangjingyuan Kong, Nan Cao, Meng Zhang, Zhen-Zhen Xu, Xue-Chun Tang, Rui-Juan Gao, Yang Wang, Qin-Yi Chen, Liang Zhang, Chao-Yang Tan, Jun-qiang Si
Publikováno v:
Molecular Neurobiology
Increasing evidence suggests that transmembrane protein 16A (TMEM16A) in nociceptive neurons is an important molecular component contributing to peripheral pain transduction. The present study aimed to evaluate the role and mechanism of TMEM16A in ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166dcf7cd2dccefc253db489879d3f9c
http://europepmc.org/articles/PMC8599235
http://europepmc.org/articles/PMC8599235
Autor:
Nan Cao, Nigala Aikeremu, Wen-Yan Shi, Xue-Chun Tang, Rui-Juan Gao, Liang-Jing-Yuan Kong, Jing-Rong Zhang, Wen-Juan Qin, Ai-Mei Zhang, Ke-Tao Ma, Li Li, Jun-Qiang Si
Publikováno v:
International journal of molecular medicine. 50(3)
The investigation of effective therapeutic drugs for pulmonary hypertension (PH) is critical. KIR2.1 plays crucial roles in regulating cell proliferation and migration, and vascular remodeling. However, researchers have not yet clearly determined whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac0f0048ee4f54cfb457e06601fdca4
https://pubmed.ncbi.nlm.nih.gov/35856410
https://pubmed.ncbi.nlm.nih.gov/35856410
Autor:
Li Li, Ai-Mei Zhang, Zi-Ting Dang, Tian Tian, Qihua Jia, Nan Cao, Ke-Tao Ma, Xue-Chun Tang, Rui-Juan Gao, Jun-qiang Si, Jingrong Zhang
Publikováno v:
Pulmonary pharmacologytherapeutics. 70
Background Recent studies have shown that endothelin-1 and angiotensin II (AngII) can increase gap junctional intercellular communication (GJIC) by activating Mitogen-activated protein kinases (MAPKs) pathway. However, not only the precise interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4542af1595c6d5b00fc1ad416d09f7
https://pubmed.ncbi.nlm.nih.gov/34428599
https://pubmed.ncbi.nlm.nih.gov/34428599
Autor:
Li Li, Wenjuan Qin, Jingrong Zhang, Ketao Ma, Rui-Juan Gao, Liangjingyuan Kong, Jun-Qiang Si, Na Hu, Xue-Chun Tang, Nan Cao, Ai-Mei Zhang
Publikováno v:
Life sciences. 274
Pulmonary vascular remodelling is one of the most important factors for pulmonary hypertension (PH). Galectin-3 (Gal-3) is a β-galactoside-binding lectin. In the latest literature, Gal-3 has been reported to be involved in pulmonary vascular remodel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33632920904c0e6b9ec2a89f656d7398
https://pubmed.ncbi.nlm.nih.gov/33716065
https://pubmed.ncbi.nlm.nih.gov/33716065
Publikováno v:
Oncotarget
Recent studies have shown that MMP-14 is highly expressed in a panel of human solid tumors and poses as a potential molecular target for anticancer drugs. Currently, major strategies for targeted therapeutics have mainly focused on the use of antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1d185437d6f96dd13584f62d5a1020
https://doi.org/10.18632/oncotarget.4709
https://doi.org/10.18632/oncotarget.4709
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 117:105-116
Gelatinases play important roles in tumour invasion and metastasis and are thus considered promising targets for cancer therapy. In this study, a new single-chain variable fragment (scFv)-based fusion protein Fv-LDP, composed of the anti-gelatinases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e249ab171690e9569a995dc0f1c89b74
https://doi.org/10.1111/bcpt.12379
https://doi.org/10.1111/bcpt.12379
Publikováno v:
European Journal of Pharmaceutical Sciences. 47:781-789
Arginine-rich peptides belong to a subclass of cell penetrating peptides that are taken up by living cells and can be detected freely diffusing inside the cytoplasm and nucleoplasm. This phenomenon has been attributed to either an endocytotic mode of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78a27dfb5d933313ff1bb745dc86075
https://doi.org/10.1016/j.ejps.2012.09.002
https://doi.org/10.1016/j.ejps.2012.09.002