Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Rui‐Rui Yang"'
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundParkinson’s disease (PD) is a prevalent disorder of the central nervous system, marked by the degeneration of dopamine (DA) neurons in the ventral midbrain. In the pathogenesis of PD, inflammation hypothesis has been concerned. This study
Externí odkaz:
https://doaj.org/article/27bb677d0745472883a11c285884c511
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Cluster headache (CH) is a common primary headache that severely impacts patients’ quality of life, characterized by recurrent, severe, unilateral headaches often centered around the eyes, temples, or forehead. Distinguishing CH from other headache
Externí odkaz:
https://doaj.org/article/cebd864a72f1401eb6053b8a5fff4d28
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background COVID-19, the current global pandemic caused by SARS-CoV-2 infection, can damage the heart and lead to heart failure (HF) and even cardiac death. The 2',5'-oligoadenylate synthetase (OAS) gene family encode interferon (IFN)-induce
Externí odkaz:
https://doaj.org/article/ddffe4034b644e9197b56a0dacd008bb
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundOAS gene family plays an important role in antiviral process, but its role in pancreatic cancer has not yet been studied.MethodsWe analyzed the expression, prognostic value and biological function of the OAS gene family in human pancreatic
Externí odkaz:
https://doaj.org/article/d31cacc1bb8e4a028ab31e8a6b2fcc01
Publikováno v:
Open Biology, Vol 11, Iss 12 (2021)
The myeloid differentiation factor 2 (MD-2)-related lipid-recognition protein is involved in immune responses through recognizing bacteria lipopolysaccharide in mammals, arthropods and plants. However, the physiological roles of MD-2 in other biologi
Externí odkaz:
https://doaj.org/article/56692a52f35542bd821bab0529817c1d
Publikováno v:
Open Biology, Vol 11, Iss 2 (2021)
Non-ATPase regulatory subunits (Rpns) are components of the 26S proteasome involved in polyubiquitinated substrate recognition and deubiquitination in eukaryotes. Here, we identified 15 homologues sequences of Rpn and associated genes by searching th
Externí odkaz:
https://doaj.org/article/5ccc86af7d8f47cab124059b287e2afa
Publikováno v:
Insects, Vol 11, Iss 9, p 642 (2020)
The brown planthopper Nilaparvata lugens is a typical monophagous insect herbivore that feeds exclusively on rice sap. This insect pest causes serious damage to rice crops throughout East Asian countries. Chemical control remains the first choice for
Externí odkaz:
https://doaj.org/article/a6eff43ed791409f83bb921212f776cb
Autor:
Jing-Yi, Zhou, Rui-Rui, Yang, Jie, Chang, Jia, Song, Zi-Sheng, Fan, Ying-Hui, Zhang, Cheng-Hao, Lu, Hua-Liang, Jiang, Ming-Yue, Zheng, Su-Lin, Zhang
Publikováno v:
Acta Pharmacologica Sinica. 44:475-485
The B-cell lymphoma 2 (BCL-2) protein family plays a pivotal role in regulating the apoptosis process. BCL-2, as an antiapoptotic protein in this family, mediates apoptosis resistance and is an ideal target for cell death strategies in cancer therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adaf22499c4e65de6b1abc755d2c9fec
https://doi.org/10.1038/s41401-022-00936-0
https://doi.org/10.1038/s41401-022-00936-0
Background COVID-19, the current global pandemic caused by SARS-CoV-2 infection, can damage the heart and lead to heart failure (HF) and even cardiac death. The 2',5'-oligoadenylate synthetase (OAS) gene family encode interferon (IFN)-induced antivir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d632a3d82d28c85acb8659a5546a3db
https://doi.org/10.21203/rs.3.rs-2142806/v1
https://doi.org/10.21203/rs.3.rs-2142806/v1
Autor:
Jia Song, Rui-rui Yang, Jie Chang, Ya-dan Liu, Cheng-hao Lu, Li-fan Chen, Hao Guo, Ying-hui Zhang, Zi-sheng Fan, Jing-yi Zhou, Gui-zhen Zhou, Ke-ke Zhang, Xiao-min Luo, Kai-xian Chen, Hua-liang Jiang, Su-lin Zhang, Ming-yue Zheng
Publikováno v:
Acta pharmacologica Sinica.
Cyclic GMP-AMP synthase (cGAS), a cytosolic DNA sensor, acts as a nucleotidyl transferase that catalyzes ATP and GTP to form cyclic GMP-AMP (cGAMP) and plays a critical role in innate immunity. Hyperactivation of cGAS-STING signaling contributes to h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0ff544a594b503f89e956a5e12b1c7
https://pubmed.ncbi.nlm.nih.gov/36229599
https://pubmed.ncbi.nlm.nih.gov/36229599