Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Rui‐Chao Chai"'
Autor:
Rui-Chao Chai, Yu-Zhou Chang, Xin Chang, Bo Pang, Song Yuan An, Ke-Nan Zhang, Yuan-Hao Chang, Tao Jiang, Yong-Zhi Wang
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-16 (2021)
Abstract Background The prognosis for diffuse gliomas is very poor and the mechanism underlying their malignant progression remains unclear. Here, we aimed to elucidate the role and mechanism of the RNA N6,2′-O-dimethyladenosine (m6A) reader, YTH N
Externí odkaz:
https://doaj.org/article/2e2649ec68d14cc88e5420d0becd1d92
Autor:
Yao‐Wu Zhang, Rui‐Chao Chai, Ren Cao, Wen‐Ju Jiang, Wei‐Hao Liu, Yu‐Lun Xu, Jun Yang, Yong‐Zhi Wang, Wen‐Qing Jia
Publikováno v:
Cancer Medicine, Vol 9, Iss 19, Pp 6996-7006 (2020)
Abstract Background Due to their rarity, the clinicopathological characteristics and prognostic factors of spinal cord gliomas are still unclear. Here, we aimed to clarify these issues in a cohort of 108 spinal cord astrocytomas. Methods We character
Externí odkaz:
https://doaj.org/article/041549128ed246a3a5d9e1e6b07a83db
Autor:
Fan Wu, Zhi‐Liang Wang, Kuan‐Yu Wang, Guan‐Zhang Li, Rui‐Chao Chai, Yu‐Qing Liu, Hao‐Yu Jiang, You Zhai, Yue‐Mei Feng, Zheng Zhao, Wei Zhang
Publikováno v:
Molecular Oncology, Vol 14, Iss 9, Pp 2081-2095 (2020)
Transcriptomic data derived from bulk sequencing have been applied to delineate the tumor microenvironment (TME) and define immune subtypes in various cancers, which may facilitate the design of immunotherapy treatment strategies. We herein gathered
Externí odkaz:
https://doaj.org/article/238a5db78908445a9967a767b7c5a9e8
Autor:
Rui-Chao Chai, Yao-Wu Zhang, Yu-Qing Liu, Yu-Zhou Chang, Bo Pang, Tao Jiang, Wen-Qing Jia, Yong-Zhi Wang
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-11 (2020)
Abstract Due to the rare incidence of spinal cord astrocytomas, their molecular features remain unclear. Here, we characterized the landscapes of mutations in H3 K27M, isocitrate dehydrogenase 1 (IDH1) R132H, BRAF V600E, and the TERT promoter in 83 d
Externí odkaz:
https://doaj.org/article/0b7f7127fe4d47ccb41ee2e50c36a164
Autor:
Rui-Chao Chai, Ning Wang, Yu-Zhou Chang, Ke-Nan Zhang, Jing-Jun Li, Jun-Jie Niu, Fan Wu, Yu-Qing Liu, Yong-Zhi Wang
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Abnormal expression of the eukaryotic initiation factor 3 (eIF3) subunits plays critical roles in tumorigenesis and progression, and also has potential prognostic value in cancers. However, the expression and clinical implications
Externí odkaz:
https://doaj.org/article/505ba8246d494af8bab8f35b6ccbbb50
Autor:
Yu-Zhou Chang, Guan-Zhang Li, Bo Pang, Ke-Nan Zhang, Xiao-Hui Zhang, Yong-Zhi Wang, Zhong-li Jiang, Rui-Chao Chai
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Isocitric dehydrogenase (IDH)-wild type diffuse gliomas, which have a poorer prognosis than their IDH-mutant counterparts, are also accompanied with high heterogeneity. Here, we aimed to identify the key biological processes associated with the three
Externí odkaz:
https://doaj.org/article/11a7d0a737364356bc0bffadb523be1e
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Objectives: In the present study, we aimed to determine the candidate genes that may function as biomarkers to further distinguish patients with isocitrate dehydrogenase (IDH)-wildtype glioblastoma (GBM), which are heterogeneous with respect to clini
Externí odkaz:
https://doaj.org/article/04117a6b33e74512b2991550ab25b622
Autor:
Rui-Chao Chai, Yu-Zhou Chang, Qiang-Wei Wang, Ke-Nan Zhang, Jing-Jun Li, Hua Huang, Fan Wu, Yu-Qing Liu, Yong-Zhi Wang
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Glioblastoma (GBM) is the most malignant glioma, with a median overall survival (OS) of 14–16 months. Temozolomide (TMZ) is the first-line chemotherapy drug for glioma, but whether TMZ should be withheld from patients with GBMs that lack O6-methylg
Externí odkaz:
https://doaj.org/article/7ef1f90bf01145e0948a4a86fd4b4b0e
Autor:
Qianghu Wang, Tao Jiang, Roel G.W. Verhaak, Yongping You, Hongbing Shen, Zhibin Hu, Siyuan Zheng, Baoli Hu, Sali Lv, Xu Qian, Xiuxing Wang, Lang Hu, Fan Lin, Ruohan Zhang, Bin Huang, Yuan Liang, Yun Cai, Tingting Zhang, Rashmi Srivastava, Han Zou, Xiangwei Xiao, Yinan Jiang, Apeng Chen, Kening Li, Jie Li, Ziyu Wang, Quanzhong Liu, Xiaoguang Qiu, Wei Zhang, Rui-Chao Chai, Yuxin Du, Fengqi Zhou, Fan Wu, Min Wu, Mengyan Zhu, Liangyu Li, Zheng Zhao, Junxia Zhang, Wei Wu, Lingxiang Wu
Supplementary Table from Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b6fa9268906854319692fc1d898cc8
https://doi.org/10.1158/2159-8290.22541997
https://doi.org/10.1158/2159-8290.22541997
Autor:
Qianghu Wang, Tao Jiang, Roel G.W. Verhaak, Yongping You, Hongbing Shen, Zhibin Hu, Siyuan Zheng, Baoli Hu, Sali Lv, Xu Qian, Xiuxing Wang, Lang Hu, Fan Lin, Ruohan Zhang, Bin Huang, Yuan Liang, Yun Cai, Tingting Zhang, Rashmi Srivastava, Han Zou, Xiangwei Xiao, Yinan Jiang, Apeng Chen, Kening Li, Jie Li, Ziyu Wang, Quanzhong Liu, Xiaoguang Qiu, Wei Zhang, Rui-Chao Chai, Yuxin Du, Fengqi Zhou, Fan Wu, Min Wu, Mengyan Zhu, Liangyu Li, Zheng Zhao, Junxia Zhang, Wei Wu, Lingxiang Wu
Supplementary Data from Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cfb62acaf70336f54bcee16edd94ed
https://doi.org/10.1158/2159-8290.22542009
https://doi.org/10.1158/2159-8290.22542009