Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Rui, Bernardes"'
Autor:
Ana Batista, Pedro Guimarães, João Martins, Paula I. Moreira, António Francisco Ambrósio, Miguel Castelo-Branco, Pedro Serranho, Rui Bernardes
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Externí odkaz:
https://doaj.org/article/61af8db1d68148efa888d0d3dbf83363
Autor:
Pedro Guimarães, Pedro Serranho, João V. Duarte, Joana Crisóstomo, Carolina Moreno, Leonor Gomes, Rui Bernardes, Miguel Castelo-Branco
Publikováno v:
Frontiers in Neuroinformatics, Vol 17 (2024)
IntroductionThere is a need to better understand the neurophysiological changes associated with early brain dysfunction in Type 2 diabetes mellitus (T2DM) before vascular or structural lesions. Our aim was to use a novel unbiased data-driven approach
Externí odkaz:
https://doaj.org/article/2dcdf4f8e77a4d559055a8c46870b26a
Autor:
Hugo Ferreira, Pedro Serranho, Pedro Guimarães, Rita Trindade, João Martins, Paula I. Moreira, António Francisco Ambrósio, Miguel Castelo-Branco, Rui Bernardes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract The early diagnosis of neurodegenerative disorders is still an open issue despite the many efforts to address this problem. In particular, Alzheimer’s disease (AD) remains undiagnosed for over a decade before the first symptoms. Optical co
Externí odkaz:
https://doaj.org/article/42450e8b9f694be5953cea0211e412a2
Autor:
Ana Batista, Pedro Guimarães, João Martins, Paula I. Moreira, António Francisco Ambrósio, Miguel Castelo-Branco, Pedro Serranho, Rui Bernardes
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Animal models of disease are paramount to understand retinal development, the pathophysiology of eye diseases, and to study neurodegeneration using optical coherence tomography (OCT) data. In this study, we present a comprehensive normative database
Externí odkaz:
https://doaj.org/article/83bf9c761e2847f2a0f380954acccc26
Autor:
Ana Batista, Pedro Guimarães, Pedro Serranho, Ana Nunes, João Martins, Paula I. Moreira, António Francisco Ambrósio, Miguel Morgado, Miguel Castelo-Branco, Rui Bernardes
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
There is a pressing need for novel diagnostic and progression biomarkers of neurodegeneration. However, the inability to determine disease duration and stage in patients with Alzheimer’s disease (AD) hinders their discovery. Because animal models o
Externí odkaz:
https://doaj.org/article/f6dae48a28124f9aa23431a24e676182
Publikováno v:
Journal of Mathematics in Industry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Understanding the physical basis of corneal transparency has been a subject of interest amongst physicists, basic scientists and ophthalmologists. Impairment of corneal clarity is a significant cause of visual morbidity worldwide. Thus, it i
Externí odkaz:
https://doaj.org/article/640163fdfba74f3e8cc571ed9f8bb011
Autor:
Ana Nunes, Pedro Serranho, Pedro Guimarães, João Ferreira, Miguel Castelo-Branco, Rui Bernardes
Publikováno v:
Journal of Imaging, Vol 10, Iss 1, p 6 (2023)
Background: Retinal texture has gained momentum as a source of biomarkers of neurodegeneration, as it is sensitive to subtle differences in the central nervous system from texture analysis of the neuroretina. Sex differences in the retina structure,
Externí odkaz:
https://doaj.org/article/bbfe001d71a94b5babb421d2abfe3963
Autor:
Ana Batista, Pedro Serranho, Mário J. Santos, Carlos Correia, José P. Domingues, Custódio Loureiro, João Cardoso, Sílvia Barbeiro, Miguel Morgado, Rui Bernardes
Publikováno v:
Sensors, Vol 23, Iss 8, p 3974 (2023)
Robust methods to compute tissue displacements in optical coherence elastography (OCE) data are paramount, as they play a significant role in the accuracy of tissue elastic properties estimation. In this study, the accuracy of different phase estimat
Externí odkaz:
https://doaj.org/article/2e19e7fe48c14fc99204d23dc9c7a368
Autor:
Pedro Guimarães, Pedro Serranho, João Martins, Paula I. Moreira, António Francisco Ambrósio, Miguel Castelo-Branco, Rui Bernardes
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
The retina, as part of the central nervous system (CNS), can be the perfect target for in vivo, in situ, and noninvasive neuropathology diagnosis and assessment of therapeutic efficacy. It has long been established that several age-related brain chan
Externí odkaz:
https://doaj.org/article/340b70aafd74417d855cf1d3048550f7
Autor:
Lília Jorge, Nádia Canário, Ricardo Martins, Beatriz Santiago, Isabel Santana, Hugo Quental, Francisco Ambrósio, Rui Bernardes, Miguel Castelo-Branco
Publikováno v:
Neural Plasticity, Vol 2020 (2020)
The retina may serve as putative window into neuropathology of synaptic loss in Alzheimer’s disease (AD). Here, we investigated synapse-rich layers versus layers composed by nuclei/cell bodies in an early stage of AD. In addition, we examined the a
Externí odkaz:
https://doaj.org/article/b05a37efb8374dc0809a9911f51b6df4