Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ruhollah Moussavi-Baygi"'
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93709 (2014)
While much has been devoted to the study of transport mechanisms through the nuclear pore complex (NPC), the specifics of interactions and binding between export transport receptors and the NPC periphery have remained elusive. Recent work has demonst
Externí odkaz:
https://doaj.org/article/dcca44e1138a48b6af954d67ca6d8f7c
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 6, p e1002049 (2011)
The nuclear pore complex (NPC) regulates molecular traffic across the nuclear envelope (NE). Selective transport happens on the order of milliseconds and the length scale of tens of nanometers; however, the transport mechanism remains elusive. Centra
Externí odkaz:
https://doaj.org/article/6e7f3fff1728424ba889c832f7ab5673
Autor:
Brian J Woo, Ruhollah Moussavi-Baygi, Heather Karner, Mehran Karimzadeh, Kristle Garcia, Tanvi Joshi, Keyi Yin, Albertas Navickas, Luke A. Gilbert, Bo Wang, Hosseinali Asgharian, Felix Y. Feng, Hani Goodarzi
Large-scale sequencing efforts of thousands of tumor samples have been undertaken to understand the mutational landscape of the coding genome. However, the vast majority of germline and somatic variants occur within non-coding portions of the genome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11a6ebf39887d74e1b58a90cbdaf857e
https://doi.org/10.1101/2023.04.14.535921
https://doi.org/10.1101/2023.04.14.535921
Autor:
Hengameh Shams, Mohammad Soheilypour, Ruhollah Moussavi-Baygi, Mohaddeseh Peyro, Mohammad R. K. Mofrad
Publikováno v:
ACS biomaterials science & engineering, vol 3, iss 11
Shams, H; Soheilypour, M; Peyro, M; Moussavi-Baygi, R; & Mofrad, MRK. (2017). Looking "under the Hood" of Cellular Mechanotransduction with Computational Tools: A Systems Biomechanics Approach across Multiple Scales. ACS Biomaterials Science and Engineering, 3(11), 2712-2726. doi: 10.1021/acsbiomaterials.7b00117. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/2xc1d946
Shams, H; Soheilypour, M; Peyro, M; Moussavi-Baygi, R; & Mofrad, MRK. (2017). Looking "under the Hood" of Cellular Mechanotransduction with Computational Tools: A Systems Biomechanics Approach across Multiple Scales. ACS Biomaterials Science and Engineering, 3(11), 2712-2726. doi: 10.1021/acsbiomaterials.7b00117. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/2xc1d946
© 2017 American Chemical Society. Signal modulation has been developed in living cells throughout evolution to promote utilizing the same machinery for multiple cellular functions. Chemical and mechanical modules of signal transmission and transduct
Autor:
Karen E. Knudsen, Nupam P. Mahajan, Housheng Hansen He, Martin Sjöström, Kathleen E. Houlahan, Jianhua Luo, S. Laura Chang, Meng Zhang, Kim N. Chi, Paul C. Boutros, Joseph F. Costello, Adam Foye, Denise Playdle, Lawrence Fong, M. Yvonne Kim, Serafim Batzoglou, Martin E. Gleave, Rahul Aggarwal, Li Zhang, Eric D. Chow, Scott A. Tomlins, Felix Y. Feng, Jiaoti Huang, Franklin W. Huang, Hui Li, Haolong Li, George Thomas, Junjie Tony Hua, Irfan A. Asangani, Marc D. Perry, Ha X. Dang, Todd M. Morgan, Robert E. Reiter, Alexander W. Wyatt, Shahneen Sandhu, Amina Zoubeidi, Christopher G. Maher, Daniel E. Spratt, Tanushree R. Shenoy, Luke A. Gilbert, Arul M. Chinnaiyan, Joshi J. Alumkal, Scott M. Dehm, Phillip G. Febbo, Primo N. Lara, Tomasz M. Beer, Adina M. Bailey, Rajdeep Das, Owen N. Witte, Alan Ashworth, Lisa N. Chesner, Joshua M. Lang, Mohammed Alshalalfa, Eric J. Small, Rohit Bose, Wilbert Zwart, David A. Quigley, Christopher P. Evans, Arnold Liao, Shuang G. Zhao, Yu Jia Shiah, Kyle Kai-How Farh, Hani Goodarzi, Travis J. Barnard, William S. Chen, Rendong Yang, Jonathan Chou, Ruhollah Moussavi-Baygi, Matthew Rettig
Publikováno v:
Nature genetics
Nature genetics, vol 52, iss 8
Nature genetics, vol 52, iss 8
Although DNA methylation is a key regulator of gene expression, the comprehensive methylation landscape of metastatic cancer has never been defined. Through whole-genome bisulfite sequencing paired with deep whole-genome and transcriptome sequencing
Autor:
Eric J. Small, Lawrence Fong, Karen E. Knudsen, Brad Sickler, Robert E. Reiter, Charles J. Ryan, Theodore C. Goldstein, Tomasz M. Beer, Martin E. Gleave, Rahul Aggarwal, Julian S. Gehring, Rajdeep Das, John Shon, Scott M. Dehm, Alan Ashworth, David A. Quigley, Ha X. Dang, Terence W. Friedlander, R. Keira Cheetham, Denise Playdle, Paul Lloyd, Serafim Batzoglou, Jack F. Youngren, Jin Zhang, Nathan A. Lack, Adam Foye, Felix Y. Feng, Jörg Hakenberg, Adina M. Bailey, Owen N. Witte, Abhijit Parolia, Scott A. Tomlins, Travis J. Barnard, Donavan T. Cheng, Jiaoti Huang, Li Zhang, P. G. Febbo, Alexander W. Wyatt, Kim N. Chi, Matthew Rettig, Vishal Kothari, Daniel E. Spratt, Housheng Hansen He, Haolong Li, George Thomas, Arnold Liao, Shuang G. Zhao, Hui Li, Joshua M. Stuart, Won Kim, Primo N. Lara, Christopher G. Maher, Jonathan Chou, Joshi J. Alumkal, Amina Zoubeidi, Marc D. Perry, Ruhollah Moussavi-Baygi, Luke A. Gilbert, Arul M. Chinnaiyan, Christopher P. Evans, Hani Goodarzi, Marcin Cieslik, Kyle Kai-How Farh
Publikováno v:
Cell, vol 174, iss 3
Quigley, DA; Dang, HX; Zhao, SG; Lloyd, P; Aggarwal, R; Alumkal, JJ; et al.(2018). Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. Cell, 174(3), 758-769.e9. doi: 10.1016/j.cell.2018.06.039. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/796124qb
Quigley, DA; Dang, HX; Zhao, SG; Lloyd, P; Aggarwal, R; Alumkal, JJ; et al.(2018). Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. Cell, 174(3), 758-769.e9. doi: 10.1016/j.cell.2018.06.039. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/796124qb
© 2018 Elsevier Inc. While mutations affecting protein-coding regions have been examined across many cancers, structural variants at the genome-wide level are still poorly defined. Through integrative deep whole-genome and -transcriptome analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1928a409b1341bcafb393804416865b5
https://escholarship.org/uc/item/796124qb
https://escholarship.org/uc/item/796124qb
Publikováno v:
Scientific Reports
Conformational behavior of intrinsically disordered proteins, such as Phe-Gly repeat domains, alters drastically when they are confined in and tethered to, nan channels. This has challenged our understanding of how they serve to selectively facilitat
Publikováno v:
Biophysical Journal. 114:555a
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 6, p e1002049 (2011)
PLoS computational biology, vol 7, iss 6
PLoS Computational Biology, vol 7, iss 6
PLoS Computational Biology
PLoS computational biology, vol 7, iss 6
PLoS Computational Biology, vol 7, iss 6
PLoS Computational Biology
The nuclear pore complex (NPC) regulates molecular traffic across the nuclear envelope (NE). Selective transport happens on the order of milliseconds and the length scale of tens of nanometers; however, the transport mechanism remains elusive. Centra
Publikováno v:
Biophysical journal. 100(6)
The nuclear pore complex (NPC) is the gatekeeper of the nucleus, capable of actively discriminating between the active and inert cargo while accommodating a high rate of translocations. The biophysical mechanisms underlying transport, however, remain