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pro vyhledávání: '"Ruhiye Cay"'
Autor:
Annette Sindram, Claudia D. Baldus, Olga Blau, Igor Wolfgang Blau, Bernd Dörken, Antonio Pezzutto, Rimma Berenstein, Asiye Kar, Sophie Schlabitz, Ruhiye Cay, Claudia Seide
Publikováno v:
Blood. 122:2627-2627
Abnormal epigenetic regulation has been implicated in oncogenesis. Mutations in the DNA methyltransferase 3A (DNMT3A) gene were recently demonstrated in acute myeloid leukemia (AML) as a candidate for the initiating of lesions in AML with adverse cli
Autor:
Igor Wolfgang Blau, Annette Sindram, Asiye Kar, Olga Blau, Ruhiye Cay, Claudia Seide, Rimma Berenstein
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Background Mutations in epigenetic modifiers were reported in patients with acute myeloid leukaemia (AML) including mutations in DNA methyltransferase 3A gene (DNMT3A) in 20%-30% patients and mutations in isocitrate dehydrogenase 1/2 gene (IDH1/2) in