Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial.

Autor: Denkinger CM; Division of Infectious Disease and Tropical Medicine, Department of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany. Claudia.Denkinger@uni-heidelberg.de.; Partner site Heidelberg University Hospital, German Center for Infection Research, Heidelberg, Germany. Claudia.Denkinger@uni-heidelberg.de., Janssen M; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Schäkel U; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Gall J; NCT Trial Center, National Center for Tumor Diseases, Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany., Leo A; Institute for Clinical Transfusion Medicine and Cell Therapy Heidelberg, Heidelberg, Germany., Stelmach P; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Weber SF; Division of Infectious Disease and Tropical Medicine, Department of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany., Krisam J; Institute of Medical Biometry, University of Heidelberg, Heidelberg, Germany., Baumann L; Institute of Medical Biometry, University of Heidelberg, Heidelberg, Germany., Stermann J; Institute of Medical Biometry, University of Heidelberg, Heidelberg, Germany., Merle U; Department of Internal Medicine IV, Heidelberg University Hospital, Heidelberg, Germany., Weigand MA; Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany., Nusshag C; Department of Nephrology, University of Heidelberg, Heidelberg, Germany., Bullinger L; Department of Hematology, Oncology and Tumor Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Schrezenmeier JF; Department of Hematology, Oncology and Tumor Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Bornhäuser M; Department of Internal Medicine I, University Hospital Dresden and Faculty of Medicine Carl Gustav Carus of TU Dresden, Dresden, Germany., Alakel N; Department of Internal Medicine I, University Hospital Dresden and Faculty of Medicine Carl Gustav Carus of TU Dresden, Dresden, Germany., Witzke O; Department of Infectious Diseases, West German Centre for Infectious Diseases, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Wolf T; Department of Internal Medicine, Infectious Diseases, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany., Vehreschild MJGT; Department of Internal Medicine, Infectious Diseases, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany., Schmiedel S; Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Addo MM; Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Partner site Hamburg-Lübeck-Borstel-Riems, German Center for Infection Research, Hamburg, Germany.; University Medical Center Hamburg-Eppendorf, Institute for Infection Research and Vaccine Development, Hamburg, Germany., Herth F; Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg and Translational Lung Research Center, Heidelberg, Germany., Kreuter M; Center for Interstitial and Rare Lung Diseases, Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg and German Center for Lung Research, Heidelberg, Germany., Tepasse PR; Department of Medicine B, Gastroenterology and Hepatology, University Hospital Münster, Münster, Germany., Hertenstein B; Medical Department I, Klinikum Bremen-Mitte, Bremen, Germany., Hänel M; Department of Internal Medicine III, Klinikum Chemnitz, Chemnitz, Germany., Morgner A; Department of Internal Medicine III, Klinikum Chemnitz, Chemnitz, Germany., Kiehl M; Department of Internal Medicine I, Frankfurt (Oder) General Hospital, Frankfurt (Oder), Germany., Hopfer O; Department of Internal Medicine I, Frankfurt (Oder) General Hospital, Frankfurt (Oder), Germany., Wattad MA; Department of Hematology, Oncology, Palliative Care and Stem Cell Transplantation, Klinikum Hochsauerland, Meschede, Germany., Schimanski CC; Department of Internal Medicine II, Klinikum Darmstadt, Darmstadt, Germany., Celik C; Department of Internal Medicine II, Klinikum Darmstadt, Darmstadt, Germany., Pohle T; Department of Internal Medicine I, Klinikum Herford, Herford, Germany., Ruhe M; Department of Internal Medicine I, Klinikum Herford, Herford, Germany., Kern WV; Department of Medicine II, Division of Infectious Diseases and Travel Medicine, University Medical Centre Freiburg, Freiburg, Germany., Schmitt A; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Lorenz HM; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Souto-Carneiro M; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Gaeddert M; Division of Infectious Disease and Tropical Medicine, Department of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany., Halama N; Department of Medical Oncology, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.; Department of Translational Immunotherapy (D240), German Cancer Research Center, Heidelberg, Germany.; Helmholtz Institute for Translational Oncology, Mainz, Germany., Meuer S; Institute for Clinical Transfusion Medicine and Cell Therapy Heidelberg, Heidelberg, Germany., Kräusslich HG; Department of Infectious Diseases, Virology, Heidelberg University Hospital, Heidelberg, Germany., Müller B; Department of Infectious Diseases, Virology, Heidelberg University Hospital, Heidelberg, Germany., Schnitzler P; Department of Infectious Diseases, Virology, Heidelberg University Hospital, Heidelberg, Germany., Parthé S; Department of Infectious Diseases, Virology, Heidelberg University Hospital, Heidelberg, Germany., Bartenschlager R; Department of Infectious Diseases, Molecular Virology, Heidelberg University Hospital, Heidelberg, Germany., Gronkowski M; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Klemmer J; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Schmitt M; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Dreger P; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Kriegsmann K; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany., Schlenk RF; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany.; NCT Trial Center, National Center for Tumor Diseases, Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany.; Department of Medical Oncology, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany., Müller-Tidow C; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany. carsten.mueller-tidow@med.uni-heidelberg.de.; National Center for Tumor Diseases, Heidelberg, Germany. carsten.mueller-tidow@med.uni-heidelberg.de.

Publikováno v: Nature cancer [Nat Cancer] 2023 Jan; Vol. 4 (1), pp. 96-107. Date of Electronic Publication: 2022 Dec 29.

LIF-dependent survival of embryonic stem cells is regulated by a novel palmitoylated Gab1 signalling protein

Autor: Sutherland, L., Ruhe, M., Gattegno-Ho, D., Mann, K., Greaves, J., Koscielniak, M., Meek, S., Lu, Z., Waterfall, M., Taylor, R., Tsakiridis, A., Brown, H., Maciver, S.K., Joshi, A., Clinton, M., Chamberlain, L.H., Smith, A., Burdon, T.

Publikováno v: Journal of Cell Science
Sutherland, L, Ruhe, M, Gattegno-Ho, D, Mann, K, Greaves, J, Koscielniak, M, Meek, S, Lu, Z, Waterfall, M, Taylor, R, Tsakiridis, A, Brown, H, Maciver, S, Joshi, A, Clinton, M, Chamberlain, L H, Smith, A & Burdon, T 2018, ' LIF-dependent survival of embryonic stem cells is regulated by a novel palmitoylated Gab1 signalling protein ', Journal of Cell Science, vol. 131, no. 18, 222257 . https://doi.org/10.1242/jcs.222257

The cytokine leukaemia inhibitory factor (LIF) promotes self-renewal of mouse embryonic stem cells (ESCs) through activation of the transcription factor Stat3. However, the contribution of other ancillary pathways stimulated by LIF in ESCs, such as t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b865ac1addf0bc8c23343965222c5f81
https://eprints.whiterose.ac.uk/137418/1/jcs222257.full.pdf

SimplySmart_v1, a new tool for the analysis of DNA damage optimized in primary neuronal cultures.

Autor: Koirala, Sushma¹ (AUTHOR), Sharma, Harman¹ (AUTHOR), Chew, Yee Lian¹ (AUTHOR), Konopka, Anna¹ (AUTHOR) anna.konopka@flinders.edu.au

Publikováno v: BMC Bioinformatics. 10/1/2024, Vol. 25 Issue 1, p1-18. 18p.

A cell-based assay system for activators of the environmental cell stress response.

Autor: Harbottle JA; Metabolic Health Group, Obesity & Metabolic Health Theme, Rowett Institute, UK., Petrie L; Metabolic Health Group, Obesity & Metabolic Health Theme, Rowett Institute, UK., Ruhe M; Metabolic Health Group, Obesity & Metabolic Health Theme, Rowett Institute, UK., Houssen WE; Marine Biodiscovery Centre, Chemistry Department, University of Aberdeen, Aberdeen, AB24 3UE, Scotland, UK; Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, Scotland, UK., Jaspars M; Marine Biodiscovery Centre, Chemistry Department, University of Aberdeen, Aberdeen, AB24 3UE, Scotland, UK., Kolb AF; Metabolic Health Group, Obesity & Metabolic Health Theme, Rowett Institute, UK. Electronic address: a.kolb@abdn.ac.uk.

Publikováno v: Analytical biochemistry [Anal Biochem] 2020 Mar 01; Vol. 592, pp. 113583. Date of Electronic Publication: 2020 Jan 13.

PO-093 A hep-2 cell model as tool for analysing DNA double strand breaks in cancer patients

Autor: Ruhe, M., Sauer, L., Schierack, P., Dammermann, W., Deckert, M.M., Schröder, C., Roggenbuck, D., Rödiger, S.

Publikováno v: In ESMO Open 30 June-3 July 2018 3 Supplement 2:A262-A262