Functional Precision Medicine Successfully Guides Therapeutic Regimen of 'Cancer of Unknown Primary' Later Classified as Triple-Negative Breast Cancer: A Case Report.

Autor: Ruhe, Larissa¹ (AUTHOR), Heibl, Sonja² (AUTHOR), Czompo, Manfred³ (AUTHOR), Haybaeck, Johannes^4,5,6 (AUTHOR), Loskutov, Jürgen⁷ (AUTHOR), Regenbrecht, Manuela Johanna^1,7 (AUTHOR), Thaler, Josef² (AUTHOR), Wedeken, Lena⁷ (AUTHOR), Regenbrecht, Christian René Alexander^1,7,8 (AUTHOR)

Publikováno v: Case Reports in Oncology. 2024, Vol. 17 Issue 1, p490-496. 7p.

The Integrator complex regulates differential snRNA processing and fate of adult stem cells in the highly regenerative planarian Schmidtea mediterranea

Autor: Schmidt, David, Reuter, Hanna, Hüttner, Katja, Ruhe, Larissa, Rabert, Franziska, Seebeck, Florian, Irimia, Manuel, Solana, Jordi

In multicellular organisms, cell type diversity and fate depend on specific sets of transcript isoforms generated by post-transcriptional RNA processing. Here, we used Schmidtea mediterranea, a flatworm with extraordinary regenerative abilities and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=r3110ae70d66::d02850f31e12cb968946d4347de7e93f
https://radar.brookes.ac.uk/radar/items/2d1d78a4-ab26-4d4c-97f9-56ee298185e7/1/

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

The Integrator complex regulates differential snRNA processing and fate of adult stem cells in the highly regenerative planarian Schmidtea mediterranea.

Autor: Schmidt D; Max Planck Institute for Molecular Biomedicine, Münster, Germany.; Medical Faculty, University of Münster, Münster, Germany., Reuter H; Max Planck Institute for Molecular Biomedicine, Münster, Germany.; Medical Faculty, University of Münster, Münster, Germany., Hüttner K; Max Planck Institute for Molecular Biomedicine, Münster, Germany.; Medical Faculty, University of Münster, Münster, Germany., Ruhe L; Max Planck Institute for Molecular Biomedicine, Münster, Germany.; Medical Faculty, University of Münster, Münster, Germany., Rabert F; Max Planck Institute for Molecular Biomedicine, Münster, Germany.; Medical Faculty, University of Münster, Münster, Germany., Seebeck F; Max Planck Institute for Molecular Biomedicine, Münster, Germany.; Medical Faculty, University of Münster, Münster, Germany., Irimia M; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain., Solana J; Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max-Delbrück Center for Molecular Medicine, Berlin, Germany., Bartscherer K; Max Planck Institute for Molecular Biomedicine, Münster, Germany.; Medical Faculty, University of Münster, Münster, Germany.; Hubrecht Institute for Developmental Biology and Stem Cell Research, CT Utrecht, The Netherlands.

Publikováno v: PLoS genetics [PLoS Genet] 2018 Dec 17; Vol. 14 (12), pp. e1007828. Date of Electronic Publication: 2018 Dec 17 (Print Publication: 2018).