Redox double-switch cancer theranostics through Pt(IV) functionalised manganese dioxide nanostructures.

Autor: Brito B; Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, King's College London, Strand, WC2R 2LS London, UK. graeme.stasiuk@kcl.ac.uk.; School of Life Sciences, Faculty of Health Sciences, University of Hull, Cottingham Road, HU6 7RX Hull, UK.; Advanced Magnetic Theranostic Nanostructures Lab, International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330 Braga, Portugal. juan.gallo@inl.int., Ruggiero MR; Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, King's College London, Strand, WC2R 2LS London, UK. graeme.stasiuk@kcl.ac.uk., Price TW; Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, King's College London, Strand, WC2R 2LS London, UK. graeme.stasiuk@kcl.ac.uk., da Costa Silva M; Advanced Magnetic Theranostic Nanostructures Lab, International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330 Braga, Portugal. juan.gallo@inl.int., Genicio N; Advanced Magnetic Theranostic Nanostructures Lab, International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330 Braga, Portugal. juan.gallo@inl.int., Wilson AJ; Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, King's College London, Strand, WC2R 2LS London, UK. graeme.stasiuk@kcl.ac.uk., Tyurina O; Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, King's College London, Strand, WC2R 2LS London, UK. graeme.stasiuk@kcl.ac.uk., Rosecker V; Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, King's College London, Strand, WC2R 2LS London, UK. graeme.stasiuk@kcl.ac.uk., Eykyn TR; Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, King's College London, Strand, WC2R 2LS London, UK. graeme.stasiuk@kcl.ac.uk., Bañobre-López M; Advanced Magnetic Theranostic Nanostructures Lab, International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330 Braga, Portugal. juan.gallo@inl.int., Stasiuk GJ; Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, King's College London, Strand, WC2R 2LS London, UK. graeme.stasiuk@kcl.ac.uk., Gallo J; Advanced Magnetic Theranostic Nanostructures Lab, International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330 Braga, Portugal. juan.gallo@inl.int.

Publikováno v: Nanoscale [Nanoscale] 2023 Jun 30; Vol. 15 (25), pp. 10763-10775. Date of Electronic Publication: 2023 Jun 30.

Role of Transmembrane Water Exchange in Glioma Invasion/Migration: In Vivo Preclinical Study by Relaxometry at Very Low Magnetic Field.

Autor: Ruggiero MR; Molecular Imaging Center, Department of Molecular Biotechnologies and Health Sciences, University of Torino, 10124 Torino, Italy., Ait Itto H; BrainTech Lab, INSERM U1205, 38000 Grenoble, France., Baroni S; Molecular Imaging Center, Department of Molecular Biotechnologies and Health Sciences, University of Torino, 10124 Torino, Italy., Pierre S; BrainTech Lab, INSERM U1205, 38000 Grenoble, France., Boutonnat J; Grenoble Hospital, 38000 Grenoble, France., Broche LM; Aberdeen Biomedical Imaging Centre, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK., Aime S; IRCCS SDN SynLab, 80143 Naples, Italy., Berger F; BrainTech Lab, INSERM U1205, 38000 Grenoble, France., Geninatti Crich S; Molecular Imaging Center, Department of Molecular Biotechnologies and Health Sciences, University of Torino, 10124 Torino, Italy., Lahrech H; BrainTech Lab, INSERM U1205, 38000 Grenoble, France.

Publikováno v: Cancers [Cancers (Basel)] 2022 Aug 29; Vol. 14 (17). Date of Electronic Publication: 2022 Aug 29.

A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.

Autor: Ghigo A; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy.; Kither Biotech Srl, 10126, Torino, Italy., Murabito A; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy., Sala V; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy.; Kither Biotech Srl, 10126, Torino, Italy., Pisano AR; Chiesi Farmaceutici S.p.A., Corporate Pre-Clinical R&D, 43122 Parma, Italy., Bertolini S; Chiesi Farmaceutici S.p.A., Corporate Pre-Clinical R&D, 43122 Parma, Italy., Gianotti A; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy., Caci E; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy., Montresor A; Division of General Pathology, Department of Medicine, University of Verona School of Medicine , 37134 Verona, Italy.; Cystic Fibrosis Translational Research Laboratory 'Daniele Lissandrini,' Department of Medicine, University of Verona School of Medicine , 37134 Verona, Italy., Premchandar A; Department of Physiology, McGill University, Montréal, Quebec H3G 1Y6, Canada., Pirozzi F; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy.; Department of Translational Medical Sciences, Federico II University, 80131 Naples, Italy., Ren K; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy., Della Sala A; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy., Mergiotti M; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy., Richter W; Department of Biochemistry and Molecular Biology, University of South Alabama College of Medicine Mobile, AL 36688, USA., de Poel E; Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center Utrecht, 3584 EA Utrecht, Netherlands., Matthey M; Department of Systems Physiology, Medical Faculty, Ruhr University Bochum, 44801 Bochum, Germany., Caldrer S; Division of General Pathology, Department of Medicine, University of Verona School of Medicine , 37134 Verona, Italy.; Cystic Fibrosis Translational Research Laboratory 'Daniele Lissandrini,' Department of Medicine, University of Verona School of Medicine , 37134 Verona, Italy., Cardone RA; Department of Biosciences, Biotechnologies, and Biopharmaceutics, University of Bari , 70126 Bari, Italy., Civiletti F; Department of Anesthesia and Critical Care Medicine, University of Torino, Azienda Ospedaliera Città della Salute e della Scienza di Torino, 10126 Torino, Italy., Costamagna A; Department of Anesthesia and Critical Care Medicine, University of Torino, Azienda Ospedaliera Città della Salute e della Scienza di Torino, 10126 Torino, Italy., Quinney NL; Marsico Lung Institute/Cystic Fibrosis Research Center, University of North Carolina, Chapel Hill, NC 27599, USA., Butnarasu C; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy., Visentin S; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy., Ruggiero MR; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy., Baroni S; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy., Crich SG; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy., Ramel D; Institute of Metabolic and Cardiovascular Diseases, Paul Sabatier University , 31432 Toulouse, France., Laffargue M; Institute of Metabolic and Cardiovascular Diseases, Paul Sabatier University , 31432 Toulouse, France., Tocchetti CG; Department of Translational Medical Sciences, Federico II University, 80131 Naples, Italy.; Interdepartmental Center of Clinical and Translational Research (CIRCET), Federico II University, 80131 Naples, Italy.; Interdepartmental Hypertension Research Center (CIRIAPA), Federico II University, 80131 Naples, Italy., Levi R; Department of Life Sciences and Systems Biology, University of Torino, 10123 Torino, Italy., Conti M; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143, USA., Lu XY; School of life Science and Technology, Xi'an Jiaotong University, 710049 Xi'an Shaanxi, P.R. China., Melotti P; Cystic Fibrosis Center, Azienda Ospedaliera Universitaria Integrata di Verona, 37126 Verona, Italy., Sorio C; Division of General Pathology, Department of Medicine, University of Verona School of Medicine , 37134 Verona, Italy.; Cystic Fibrosis Translational Research Laboratory 'Daniele Lissandrini,' Department of Medicine, University of Verona School of Medicine , 37134 Verona, Italy., De Rose V; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy., Facchinetti F; Chiesi Farmaceutici S.p.A., Corporate Pre-Clinical R&D, 43122 Parma, Italy., Fanelli V; Department of Anesthesia and Critical Care Medicine, University of Torino, Azienda Ospedaliera Città della Salute e della Scienza di Torino, 10126 Torino, Italy., Wenzel D; Department of Systems Physiology, Medical Faculty, Ruhr University Bochum, 44801 Bochum, Germany.; Institute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, 53127 Bonn, Germany., Fleischmann BK; Institute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, 53127 Bonn, Germany., Mall MA; Department of Pediatric Respiratory Medicine, Immunology, and Critical Care Medicine, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; German Center for Lung Research (DZL), associated partner, 10117 Berlin, Germany., Beekman J; Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center Utrecht, 3584 EA Utrecht, Netherlands., Laudanna C; Division of General Pathology, Department of Medicine, University of Verona School of Medicine , 37134 Verona, Italy.; Cystic Fibrosis Translational Research Laboratory 'Daniele Lissandrini,' Department of Medicine, University of Verona School of Medicine , 37134 Verona, Italy., Gentzsch M; Marsico Lung Institute/Cystic Fibrosis Research Center, University of North Carolina, Chapel Hill, NC 27599, USA.; Department of Pediatric Pulmonology, University of North Carolina, Chapel Hill, NC 27599, USA., Lukacs GL; Department of Physiology, McGill University, Montréal, Quebec H3G 1Y6, Canada., Pedemonte N; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy., Hirsch E; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino , 10126 Torino, Italy.; Kither Biotech Srl, 10126, Torino, Italy.

Publikováno v: Science translational medicine [Sci Transl Med] 2022 Mar 30; Vol. 14 (638), pp. eabl6328. Date of Electronic Publication: 2022 Mar 30.

Low-Field NMR Relaxometry for Intraoperative Tumour Margin Assessment in Breast-Conserving Surgery.

Autor: Bitonto V; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy., Ruggiero MR; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy., Pittaro A; Pathology Unit, Department of Medical Sciences, University of Turin, 10126 Torino, Italy., Castellano I; Pathology Unit, Department of Medical Sciences, University of Turin, 10126 Torino, Italy., Bussone R; Breast Unit, Ospedale Cottolengo, 10152 Torino, Italy., Broche LM; Aberdeen Biomedical Imaging Centre, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK., Lurie DJ; Aberdeen Biomedical Imaging Centre, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK., Aime S; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.; IRCCS SDN, Via E. Gianturco 113, 80143 Napoli, Italy., Baroni S; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy., Geninatti Crich S; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.

Publikováno v: Cancers [Cancers (Basel)] 2021 Aug 17; Vol. 13 (16). Date of Electronic Publication: 2021 Aug 17.

In vivo assessment of tumour associated macrophages in murine melanoma obtained by low-field relaxometry in the presence of iron oxide particles.

Autor: Baroni S; Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza 52, Torino, Italy., Ruggiero MR; Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza 52, Torino, Italy., Bitonto V; Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza 52, Torino, Italy., Broche LM; Aberdeen Biomedical Imaging Centre, University of Aberdeen, Foresterhill, AB25 2ZD, Aberdeen, UK., Lurie DJ; Aberdeen Biomedical Imaging Centre, University of Aberdeen, Foresterhill, AB25 2ZD, Aberdeen, UK., Aime S; Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza 52, Torino, Italy; Istituto di Biostrutture e Bioimmagini (IBB), CNR, Torino, Italy., Geninatti Crich S; Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza 52, Torino, Italy. Electronic address: simonetta.geninatti@unito.it.

Publikováno v: Biomaterials [Biomaterials] 2020 Apr; Vol. 236, pp. 119805. Date of Electronic Publication: 2020 Jan 27.