Rapid Implementation of Severe Acute Respiratory Syndrome Coronavirus 2 Emergency Use Authorization RT-PCR Testing and Experience at an Academic Medical Institution

Autor: Velu, Priya, Craney, Arryn, Ruggiero, Phyllis, Sipley, John, Cong, Lin, Hissong, Erika M., Loda, Massimo, Westblade, Lars F., Cushing, Melissa, Rennert, Hanna

Publikováno v: In The Journal of Molecular Diagnostics February 2021 23(2):149-158

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Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions.

Autor: Butler DJ; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA., Mozsary C; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA., Meydan C; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, NY, USA.; WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA., Danko D; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA.; Tri-Institutional Computational Biol. & Medicine Program, Weill Cornell Medicine, NY, USA., Foox J; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, NY, USA., Rosiene J; New York Genome Center, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA., Shaiber A; New York Genome Center, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA.; Englander Institute for Precision Medicine and the Meyer Cancer Center, Weill Cornell Medicine, NY, USA., Afshinnekoo E; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, NY, USA.; WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA., MacKay M; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA., Sedlazeck FJ; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Ivanov NA; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, NY, USA.; Clinical & Translational Science Center, Weill Cornell Medicine, NY, USA., Sierra M; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA., Pohle D; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Germany., Zietz M; Department of Biomedical Informatics, Department of Systems Biology, Department of Medicine, Institute for Genomic Medicine, Columbia University, NY, USA., Gisladottir U; Department of Biomedical Informatics, Department of Systems Biology, Department of Medicine, Institute for Genomic Medicine, Columbia University, NY, USA., Ramlall V; Department of Biomedical Informatics, Department of Systems Biology, Department of Medicine, Institute for Genomic Medicine, Columbia University, NY, USA.; Department of Cellular, Molecular Physiology & Biophysics, Columbia University, NY, USA., Westover CD; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA., Ryon K; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA., Young B; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA., Bhattacharya C; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA., Ruggiero P; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA., Langhorst BW; New England Biolabs, MA, USA., Tanner N; New England Biolabs, MA, USA., Gawrys J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA., Meleshko D; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA.; Tri-Institutional Computational Biol. & Medicine Program, Weill Cornell Medicine, NY, USA., Xu D; Genomics Resources Core Facility, Weill Cornell Medicine, NY, USA., Steel PAD; Department of Emergency Medicine, Weill Cornell Medicine, NY, USA., Shemesh AJ; Department of Emergency Medicine, Weill Cornell Medicine, NY, USA., Xiang J; Genomics Resources Core Facility, Weill Cornell Medicine, NY, USA.; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, NY, USA., Thierry-Mieg J; National Center for Biotechnology Information, National Library of Medicine, National Institute of Health, MD, USA., Thierry-Mieg D; National Center for Biotechnology Information, National Library of Medicine, National Institute of Health, MD, USA., Schwartz RE; Department of Medicine, Weill Cornell Medicine, NY, USA., Iftner A; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Germany., Bezdan D; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Germany., Sipley J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA., Cong L; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA., Craney A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA., Velu P; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA., Melnick AM; Department of Medicine, Weill Cornell Medicine, NY, USA., Hajirasouliha I; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, NY, USA.; Englander Institute for Precision Medicine and the Meyer Cancer Center, Weill Cornell Medicine, NY, USA., Horner SM; Department of Molecular Genetics and Microbiology, Duke University Medical Center, NC, USA.; Department of Medicine, Duke University Medical Center, NC, USA., Iftner T; Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, Germany., Salvatore M; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, NY, USA., Loda M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA., Westblade LF; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA.; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, NY, USA., Cushing M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA., Levy S; HudsonAlpha Discovery Institute, Huntsville, AL, USA., Wu S; Hangzhou Cancer Institute, Hangzhou Cancer Hospital, Hangzhou, China.; Department of Radiation Oncology, Hangzhou Cancer Hospital, Hangzhou, China., Tatonetti N; Department of Biomedical Informatics, Department of Systems Biology, Department of Medicine, Institute for Genomic Medicine, Columbia University, NY, USA., Imielinski M; New York Genome Center, NY, USA.; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA.; Englander Institute for Precision Medicine and the Meyer Cancer Center, Weill Cornell Medicine, NY, USA., Rennert H; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, NY, USA., Mason CE; Department of Physiology and Biophysics, Weill Cornell Medicine, NY, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, NY, USA.; WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA.; The Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, NY, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2020 May 01. Date of Electronic Publication: 2020 May 01.