Zobrazeno 1 - 10
of 627
pro vyhledávání: '"Ruggerone P"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1311-1319 (2024)
Somatostatin receptors (SSTRs) are widely distributed throughout the human body and play crucial roles in various physiological processes. They are recognized as key targets for both radiotherapy and radiodiagnosis due to their overexpression in seve
Externí odkaz:
https://doaj.org/article/bf4cb9a65b0b41a1a3ea388b258a515a
Autor:
Carola Dell’Acqua, Simone Messerotti Benvenuti, Nicola Cellini, C. J. Brush, Alessandra Ruggerone, Daniela Palomba
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Depression is characterized by reduced physical activity and sleep-wake cycle disturbances, often considered important features of the disease. While a few studies have suggested that self-reported reduced physical activity and sleep-wake cy
Externí odkaz:
https://doaj.org/article/72275a84a7284602a46543416ed9c615
Autor:
Pedro D. Manrique, Inga V. Leus, César A. López, Jitender Mehla, Giuliano Malloci, Silvia Gervasoni, Attilio V. Vargiu, Rama K. Kinthada, Liam Herndon, Nicolas W. Hengartner, John K. Walker, Valentin V. Rybenkov, Paolo Ruggerone, Helen I. Zgurskaya, S. Gnanakaran
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract The ability Gram-negative pathogens have at adapting and protecting themselves against antibiotics has increasingly become a public health threat. Data-driven models identifying molecular properties that correlate with outer membrane (OM) pe
Externí odkaz:
https://doaj.org/article/45d6aee426a544c597e58b71c5e0adb4
Publikováno v:
In Computational and Structural Biotechnology Journal December 2024 23:1311-1319
Autor:
Silvia Gervasoni, Camilla Guccione, Viviana Fanti, Andrea Bosin, Giancarlo Cappellini, Bruno Golosio, Paolo Ruggerone, Giuliano Malloci
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The cyclic peptide hormone somatostatin regulates physiological processes involved in growth and metabolism, through its binding to G-protein coupled somatostatin receptors. The isoform 2 (SSTR2) is of particular relevance for the therapy of
Externí odkaz:
https://doaj.org/article/a473b2ddca09409ba9267aabd6afda3a
Autor:
Silvia Gervasoni, Jitender Mehla, Charles R. Bergen, Inga V. Leus, Enrico Margiotta, Giuliano Malloci, Andrea Bosin, Attilio V. Vargiu, Olga Lomovskaya, Valentin V. Rybenkov, Paolo Ruggerone, Helen I. Zgurskaya
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Transporters of the resistance-nodulation-cell division (RND) superfamily of proteins are the dominant multidrug efflux power of Gram-negative bacteria. The major RND efflux pump of Pseudomonas aeruginosa is MexAB-OprM, in which the inner me
Externí odkaz:
https://doaj.org/article/09f8ee5600f347ba91948b10681d1d33
Autor:
Julia Vergalli, Hugo Chauvet, Francesco Oliva, Jelena Pajović, Giuliano Malloci, Attilio Vittorio Vargiu, Matthieu Réfrégiers, Paolo Ruggerone, Jean-Marie Pagès
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A competitive efflux assay combined with computational approaches reveal how different quinolones interact with the prototypical bacterial multidrug efflux transporter AcrB, providing insights which may help optimise antibiotics.
Externí odkaz:
https://doaj.org/article/9ea12524a8cd497c89d5c583e95f6c7d
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Silvia Gervasoni, Giuliano Malloci, Andrea Bosin, Attilio V. Vargiu, Helen I. Zgurskaya, Paolo Ruggerone
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-12 (2022)
Measurement(s) molecular physical property analysis objective Technology Type(s) Computer Modeling
Externí odkaz:
https://doaj.org/article/c60297b5a8cc4382882c3b150273e333