Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Ruggero Tenni"'
Autor:
Roberta Besio, Roberta Gioia, Federica Cossu, Enrico Monzani, Stefania Nicolis, Lucia Cucca, Antonella Profumo, Luigi Casella, Ruggero Tenni, Martino Bolognesi, Antonio Rossi, Antonella Forlino
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58792 (2013)
Prolidase is the only human enzyme responsible for the digestion of iminodipeptides containing proline or hydroxyproline at their C-terminal end, being a key player in extracellular matrix remodeling. Prolidase deficiency (PD) is an intractable loss
Externí odkaz:
https://doaj.org/article/220c7167155249ec8def52abd4c9c625
Autor:
Enrica Tira, Ruggero Tenni
Publikováno v:
European Journal of Histochemistry, Vol 49, Iss 3 (2009)
XXV Meeting THE ITALIAN SOCIETY FOR THE STUDY OF CONNECTIVE TISSUES (SISC)
Externí odkaz:
https://doaj.org/article/8f8e5e8b9ff644d596160e593efb9be2
Autor:
Eric Haÿ, Martine Cohen-Solal, Silvia Lecci, Andrea Superti-Furga, Luca Monti, Fabio De Leonardis, Antonio Rossi, Antonella Forlino, Simona Villani, Ruggero Tenni, Chiara Paganini
Publikováno v:
Human Molecular Genetics, vol. 24, no. 19, pp. 5570-5580
Diastrophic dysplasia (DTD) is a recessive chondrodysplasia caused by mutations in SLC26A2, a cell membrane sulfate-chloride antiporter. Sulfate uptake impairment results in low cytosolic sulfate, leading to cartilage proteoglycan (PG) undersulfation
Autor:
Sarah Foster, Antonio Rossi, Ersilia De Lorenzi, Isabella Villa, Ruggero Tenni, Roberta Gioia, Antonella Forlino, Silvia Maruelli, Halil Ibrahim Aydin, Maja Di Rocco, Josè Luis Dapena Diaz, Charu Deshpande, Çiğdem Seher Kasapkara, Teresa M. Gunn, Nick Bishop, Mehmet Ali Gürer, Roberta Besio, Raffaella Colombo, Haether Moore-Barton, Bartłomiej Kwiek, Peter Grabowski, Orla Gallagher, Ayşegül Tokatlı, Esra Adişen, James M. Phang
Publikováno v:
Bone. 72:53-64
The degradation of the main fibrillar collagens, collagens I and II, is a crucial process for skeletal development. The most abundant dipeptides generated from the catabolism of collagens contain proline and hydroxyproline. In humans, prolidase is th
Autor:
Luca Monti, Antonio Rossi, Benedetta Gualeni, Antonella Forlino, Fabio De Leonardis, Ruggero Tenni
Publikováno v:
Journal of Cellular Biochemistry
In several skeletal dysplasias defects in extracellular matrix molecules affect not only the structural and mechanical properties of cartilage, but also the complex network of signaling pathways involved in cell proliferation and differentiation. Sul
Autor:
Luca Bini, Francesca Tonelli, Paul Witten, Fransiska Malfait, Antonio Rossi, Andy Willaert, Antonella Forlino, N. De Rocker, Björn Menten, Silvia Carra, Roberta Gioia, Claudia Landi, Sergey Leikin, A De Paepe, Paul Coucke, Assunta Gagliardi, Ann Huysseune, Ruggero Tenni, Laura Bianchi, An Staes, Kris Gevaert, Charlotte Gistelinck, Loredana Marchese
Publikováno v:
SCIENTIFIC REPORTS
Scientific Reports
Scientific Reports
Over the last years the zebrafish imposed itself as a powerful model to study skeletal diseases, but a limit to its use is the poor characterization of collagen type I, the most abundant protein in bone and skin. In tetrapods collagen type I is a tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efdb20c800a66f46a6905a9b51b1579d
https://biblio.ugent.be/publication/7901507/file/7901648
https://biblio.ugent.be/publication/7901507/file/7901648
Autor:
Roberta Besio, Vincenzo Giansanti, Giampaolo Merlini, Simona Villani, Ruggero Tenni, Isabella Villa, Cristina Panaroni, Joan C. Marini, Antonio Rossi, Roberta Gioia, Paolo Vezzoni, Antonella Forlino, Anna Villa, Ivana A. Scovassi, Giovanni Palladini
Publikováno v:
Stem Cells. 30:1465-1476
The molecular basis underlying the clinical phenotype in bone diseases is customarily associated with abnormal extracellular matrix structure and/or properties. More recently, cellular malfunction has been identified as a concomitant causative factor
Publikováno v:
Amino Acids. 35:739-752
Here we summarized what is known at the present about function, structure and effect of mutations in the human prolidase. Among the peptidases, prolidase is the only metalloenzyme that cleaves the iminodipeptides containing a proline or hydroxyprolin
Autor:
Luca Bini, Assunta Gagliardi, Silvia Carra, Laura Bianchi, Franco Cotelli, Roberta Gioia, Antonio Rossi, Antonella Forlino, Ruggero Tenni, Sergey Leikin, Shannon Fisher, Marco Biggiogera, Francesca Tonelli
Publikováno v:
Bone Abstracts.
Publikováno v:
Matrix Biology. 19:511-520
The thermal stability of the trimeric species formed by seven type I collagen CNBr peptides was determined at neutral and acidic pH. Melting temperature of peptide trimers and free energy change for monomer to trimer transition were used as indices o