Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ruggero G Fariello"'
Autor:
Marina Boido, Olena Butenko, Consuelo Filippo, Roberta Schellino, Jan W Vrijbloed, Ruggero G Fariello, Alessandro Vercelli
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0228653 (2020)
Current efforts to improve muscle performance are focused on muscle trophism via inhibition of the myostatin pathway: however they have been unsuccessful in the clinic to date. In this study, a novel protein has been created by combining the soluble
Externí odkaz:
https://doaj.org/article/806d02b576494fb286821db5fb75f973
Autor:
Stefan Hettwer, Shuo Lin, Stefan Kucsera, Monika Haubitz, Filippo Oliveri, Ruggero G Fariello, Markus A Ruegg, Jan W Vrijbloed
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88739 (2014)
Treatment of neuromuscular diseases is still an unsolved problem. Evidence over the last years strongly indicates the involvement of malformation and dysfunction of neuromuscular junctions in the development of such medical conditions. Stabilization
Externí odkaz:
https://doaj.org/article/00e9738327334c9d8d21e4265f442ff8
Autor:
Jörg Sahlmann, Isabel C. Sumaya, Ruggero G. Fariello, Federica Pericle, Donald E. Moss, Enrico Braglia
Publikováno v:
British Journal of Clinical Pharmacology
Aims To ascertain the tolerability profile of single and repeated oral doses of methanesulfonyl fluoride (MSF, SNX-001) in healthy aged subjects, and to determine the degree of erythrocyte acetylcholinesterase (AChE) inhibition induced by MSF after s
Autor:
Paolo Decina, Giovanni Caracci, Pier Luigi Scapicchio, Christopher G. Goetz, Caroline M. Tanner, Jack A. Cohen, Jean A. Thelen, V. Susan Carroll, Harold L. Klawans, Ruggero G. Fariello, Francis O. Walker, J. Michael Walker, Rae R. Matsumoto, Wayne D. Bowen, Jesse M. Cedarbaum, A. R. Crossman
Publikováno v:
Movement Disorders. 5:263-266
Autor:
Ruggero G. Fariello
Publikováno v:
Neurotherapeutics
Safinamide (SAF) ((S)-(+)-2-(4-(3-fluorobenzyloxy) benzylamino)propanamide) was initially synthetized by Farmitalia Carlo Erba (Italy). Following initial anticonvulsant screening, safinamide was selected for its potency, broad spectrum of action, and
Publikováno v:
Epilepsia. 32(2)
Summary: Single-photon emission tomography (SPECT) scanning with n-isopropyl-p-iodoamphetamine (IMP) was performed on 23 patients with complex partial seizures undergoing long-term video/electroencephalographic (EEG) seizure monitoring. Twenty-one of
Publikováno v:
Neurobiology of aging. 11(1)
Computer analysis of the EEG was obtained in the course of evaluation of 35 patients with Dementia of the Alzheimer's Type (DAT) and Huntington's disease (HD), and compared to 20 age-matched normal controls. On-line computer analysis of the EEG consi
Autor:
Ruggero G. Fariello
Publikováno v:
Experimental Neurology. 66:55-63
Epileptiform activity was induced in adult cats anesthetized with Ketamine or Na-pentobarbital. Acute models of focal epilepsy were created by application of various epileptogenic agents to neocortical or limbic structures. Inhibitory amino acids wer
Autor:
Ruggero G. Fariello, Maharaj K. Ticku
Publikováno v:
Life Sciences. 33:1629-1640
Impaired GABA-mediated inhibition is probably one of the cellular abnormalities leading to Focal Epilepsy. The role of GABA in generalized seizures, particularly of Petit Mal type, is unknown. Various approaches are available to potentiate GABA funct
Autor:
Brian H. Hoff, Ruggero G. Fariello, Daniel Hellman, David C. Flemming, James Fitzpatrick, Thomas Duff
Publikováno v:
Anesthesiology. 52:431-433