Zobrazeno 1 - 10 of 163 pro vyhledávání: '"Rufina, Schuligoi"'
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Akademický článek
The Role of PGE2 in Alveolar Epithelial and Lung Microvascular Endothelial Crosstalk
Autor: Thomas Bärnthaler, Jovana Maric, Wolfgang Platzer, Viktoria Konya, Anna Theiler, Carina Hasenöhrl, Benjamin Gottschalk, Sandra Trautmann, Yannick Schreiber, Wolfgang F. Graier, Rudolf Schicho, Gunther Marsche, Andrea Olschewski, Dominique Thomas, Rufina Schuligoi, Akos Heinemann
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Disruption of the blood-air barrier, which is formed by lung microvascular endothelial and alveolar epithelial cells, is a hallmark of acute lung injury. It was shown that alveolar epithelial cells release an unidentified soluble factor that
Externí odkaz: https://doaj.org/article/5954ae3d0f3245918a8d9c82f4b24f8b
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2
Supplemental Fibrinogen Restores Platelet Inhibitor-Induced Reduction in Thrombus Formation without Altering Platelet Function: An In Vitro Study
Autor: Gabor G. Toth, Akos Heinemann, Elisabeth Mahla, Thomas Bärnthaler, Florian Prüller, Eva Buschmann, Rufina Schuligoi
Publikováno v: Thrombosis and Haemostasis. 120:1548-1556
Background For patients treated with dual antiplatelet therapy, standardized drug-specific 3-to-7 day cessation is recommended prior to major surgery to reach sufficient platelet function recovery. Here we investigated the hypothesis that supplementa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ef75335b24f2314005b9cb920eea58
https://doi.org/10.1055/s-0040-1715445
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3
Akademický článek
Laropiprant attenuates EP3 and TP prostanoid receptor-mediated thrombus formation.
Autor: Sonia Philipose, Viktoria Konya, Mirjana Lazarevic, Lisa M Pasterk, Gunther Marsche, Sasa Frank, Bernhard A Peskar, Akos Heinemann, Rufina Schuligoi
Publikováno v: PLoS ONE, Vol 7, Iss 8, p e40222 (2012)
The use of the lipid lowering agent niacin is hampered by a frequent flush response which is largely mediated by prostaglandin (PG) D(2). Therefore, concomitant administration of the D-type prostanoid (DP) receptor antagonist laropiprant has been pro
Externí odkaz: https://doaj.org/article/ca1774a7e09446f4aca61f900f1ab9ab
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5
G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1
Autor: Johannes Haybaeck, Nerea Ferreirós, Eva M. Sturm, Carina Hasenoehrl, Stephan Beck, Magdalena Grill, Ellen Heitzer, Lee M. Butcher, Caroline Schweiger, Rudolf Schicho, Rufina Schuligoi, David Feuersinger, Ricarda Graf, Dominique Thomas, Martin Pichler, Thomas Bärnthaler
Publikováno v: International Journal of Cancer. 142:121-132
The putative cannabinoid receptor GPR55 has been shown to play a tumor-promoting role in various cancers, and is involved in many physiological and pathological processes of the gastrointestinal (GI) tract. While the cannabinoid receptor 1 (CB1 ) has
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f230d9558d5b768e21e5604fdfabe38f
https://doi.org/10.1002/ijc.31030
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8
Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival
Autor: Eva M. Sturm, Akos Heinemann, Leigh M. Marsh, Gunther Marsche, Trond Ulven, Wolfgang Platzer, Rufina Schuligoi, Thomas Bärnthaler, Sonja Rittchen, Miriam Peinhaupt, Julia Kargl, Georg Richtig, Anna Theiler
Publikováno v: Theiler, A, Bärnthaler, T, Platzer, W, Richtig, G, Peinhaupt, M, Rittchen, S, Kargl, J, Ulven, T, Marsh, L M, Marsche, G, Schuligoi, R, Sturm, E M & Heinemann, A 2019, ' Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival ', The Journal of allergy and clinical immunology, vol. 144, no. 3, pp. 764-776 . https://doi.org/10.1016/j.jaci.2019.05.002
Background Lung eosinophilia is a hallmark of asthma, and eosinophils are believed to play a crucial role in the pathogenesis of allergic inflammatory diseases. Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, are produced
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0465e716741b528d33f06e44a69525
https://curis.ku.dk/portal/da/publications/butyrate-ameliorates-allergic-airway-inflammation-by-limiting-eosinophil-trafficking-and-survival(813de5a2-52ae-478f-acc6-b30c47695578).html
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10
Activation of EP4receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function
Autor: Andrea Olschewski, Robert Frei, Leigh M. Marsh, Jovana Maric, Irmgard Th. Lippe, Wolfgang Platzer, Viktoria Konya, Thomas Bärnthaler, Ida Aringer, Gunther Marsche, Petra Luschnig, Anna Theiler, Katharina Jandl, Ilse Lanz, Akos Heinemann, Rufina Schuligoi
Publikováno v: British Journal of Pharmacology. 172:4454-4468
Background and Purpose Pulmonary vascular dysfunction is a key event in acute lung injury. We recently demonstrated that PGE2, via activation of E-prostanoid (EP)4 receptors, strongly enhances microvascular barrier function in vitro. The aim of this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6732be8ec21631cd5df4c85fa805ffbc
https://doi.org/10.1111/bph.13229
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