Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Ruffle, James K."'
Autor:
Ruffle, James K, Mohinta, Samia, Baruteau, Kelly Pegoretti, Rajiah, Rebekah, Lee, Faith, Brandner, Sebastian, Nachev, Parashkev, Hyare, Harpreet
The VASARI MRI feature set is a quantitative system designed to standardise glioma imaging descriptions. Though effective, deriving VASARI is time-consuming and seldom used in clinical practice. This is a problem that machine learning could plausibly
Externí odkaz:
http://arxiv.org/abs/2404.15318
Autor:
Ruffle, James K, Watkins, Henry, Gray, Robert J, Hyare, Harpreet, de Schotten, Michel Thiebaut, Nachev, Parashkev
The architecture of the brain is too complex to be intuitively surveyable without the use of compressed representations that project its variation into a compact, navigable space. The task is especially challenging with high-dimensional data, such as
Externí odkaz:
http://arxiv.org/abs/2310.16113
Autor:
Ruffle, James K, Gray, Robert J, Mohinta, Samia, Pombo, Guilherme, Kaul, Chaitanya, Hyare, Harpreet, Rees, Geraint, Nachev, Parashkev
Our knowledge of the organisation of the human brain at the population-level is yet to translate into power to predict functional differences at the individual-level, limiting clinical applications, and casting doubt on the generalisability of inferr
Externí odkaz:
http://arxiv.org/abs/2309.07096
Autor:
Nelson, Amy PK, Mole, Joe, Pombo, Guilherme, Gray, Robert J, Ruffle, James K, Chan, Edgar, Rees, Geraint E, Cipolotti, Lisa, Nachev, Parashkev
The quantification of cognitive powers rests on identifying a behavioural task that depends on them. Such dependence cannot be assured, for the powers a task invokes cannot be experimentally controlled or constrained a priori, resulting in unknown vu
Externí odkaz:
http://arxiv.org/abs/2308.07039
Autor:
Ruffle, James K, Mohinta, Samia, Pombo, Guilherme, Gray, Robert, Kopanitsa, Valeriya, Lee, Faith, Brandner, Sebastian, Hyare, Harpreet, Nachev, Parashkev
Tumour heterogeneity is increasingly recognized as a major obstacle to therapeutic success across neuro-oncology. Gliomas are characterised by distinct combinations of genetic and epigenetic alterations, resulting in complex interactions across multi
Externí odkaz:
http://arxiv.org/abs/2301.06111
Autor:
Elmalem, Michael S., Moody, Hanna, Ruffle, James K., de Schotten, Michel Thiebaut, Haggard, Patrick, Diehl, Beate, Nachev, Parashkev, Jha, Ashwani
The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective anatomical in
Externí odkaz:
http://arxiv.org/abs/2211.00393
Autor:
Carruthers, Robert, Straw, Isabel, Ruffle, James K, Herron, Daniel, Nelson, Amy, Bzdok, Danilo, Fernandez-Reyes, Delmiro, Rees, Geraint, Nachev, Parashkev
Equity is widely held to be fundamental to the ethics of healthcare. In the context of clinical decision-making, it rests on the comparative fidelity of the intelligence -- evidence-based or intuitive -- guiding the management of each individual pati
Externí odkaz:
http://arxiv.org/abs/2207.12043
The complex heterogeneity of brain tumours is increasingly recognized to demand data of magnitudes and richness only fully-inclusive, large-scale collections drawn from routine clinical care could plausibly offer. This is a task contemporary machine
Externí odkaz:
http://arxiv.org/abs/2206.06120
Autor:
Nelson, Amy P.K., Mole, Joe, Pombo, Guilherme, Gray, Robert J., Ruffle, James K., Chan, Edgar, Rees, Geraint E., Cipolotti, Lisa, Nachev, Parashkev
Publikováno v:
In Cortex October 2024 179:62-76
Autor:
Nelson, Amy PK, Gray, Robert J, Ruffle, James K, Watkins, Henry C, Herron, Daniel, Sorros, Nick, Mikhailov, Danil, Cardoso, M. Jorge, Ourselin, Sebastien, McNally, Nick, Williams, Bryan, Rees, Geraint E., Nachev, Parashkev
The value of biomedical research--a $1.7 trillion annual investment--is ultimately determined by its downstream, real-world impact. Current objective predictors of impact rest on proxy, reductive metrics of dissemination, such as paper citation rates
Externí odkaz:
http://arxiv.org/abs/2110.08904