Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Ruey Hwa Chen"'
Autor:
Ruei Liang Yan, Chiu Lin Luan, Chun Chieh Liao, Li Heng Liu, Fei Yun Chen, Hsin Yi Chen, Ruey Hwa Chen
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/5118ffb6c0c84fb88f36455988ab8f95
Autor:
Wei Yang Sit, Mei-Ling Cheng, Tsan-Jan Chen, Chia-Jo Chen, Bo-Nian Chen, Ding-Jun Huang, Pei-Lien Chen, Yun-Ching Chen, Chi-Jen Lo, Deng-Chyang Wu, Wan-Chen Hsieh, Chung-Ting Chang, Ruey-Hwa Chen, Wen-Ching Wang
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Helicobacter pylori, a dominant member of the gastric microbiota was associated with various gastrointestinal diseases and presents a significant challenge due to increasing antibiotic resistance. This study identifies H. pylori’s phospholipase A (
Externí odkaz:
https://doaj.org/article/663a62325ec84f488aef70da7b4ba32c
Autor:
Shaifali Singh, Nai Yang Yeat, Ya-Ting Wang, Shu-Yu Lin, I-Ying Kuo, Kuen-Phon Wu, Won-Jing Wang, Wen-Ching Wang, Wu-Chou Su, Yi-Ching Wang, Ruey-Hwa Chen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-17 (2023)
Abstract Aberrant overexpression or activation of EGFR drives the development of non-small cell lung cancer (NSCLC) and acquired resistance to EGFR tyrosine kinase inhibitors (TKIs) by secondary EGFR mutations or c-MET amplification/activation remain
Externí odkaz:
https://doaj.org/article/aaf04d699c2f45f6a88e5341ad07b036
Autor:
Shaifali Singh, Nai Yang Yeat, Ya-Ting Wang, Shu-Yu Lin, I-Ying Kuo, Kuen-Phon Wu, Won-Jing Wang, Wen-Ching Wang, Wu-Chou Su, Yi-Ching Wang, Ruey-Hwa Chen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9922c5b5578240c4ba3a59bfacda25c3
Autor:
Yu-Hsuan Chen, Han-Hsiun Chen, Won-Jing Wang, Hsin-Yi Chen, Wei-Syun Huang, Chien-Han Kao, Sin-Rong Lee, Nai Yang Yeat, Ruei-Liang Yan, Shu-Jou Chan, Kuen-Phon Wu, Ruey-Hwa Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Activation of tumor-intrinsic innate immunity has been a major strategy for improving immunotherapy. Previously, we reported an autophagy-promoting function of the deubiquitinating enzyme TRABID. Here, we identify a critical role of TRABID i
Externí odkaz:
https://doaj.org/article/11bbe81d925149b88611bf2e8f4b6922
Autor:
Pei-Rung Wu, Shang-Yin Chiang, Robert Midence, Wen-Chao Kao, Chun-Lun Lai, I-Cheng Cheng, Shen-Ju Chou, Chih-Cheng Chen, Chih-Yang Huang, Ruey-Hwa Chen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Patients with mutations of WDR4, a substrate adaptor of the CUL4 E3 ligase complex, develop cerebellar atrophy and gait phenotypes. However, the underlying mechanisms remain unexplored. Here, we identify a crucial role of Wdr4 in cerebellar
Externí odkaz:
https://doaj.org/article/bcfab74854e6422e82765ba22f9778e9
Autor:
Hsin-Yi Chen, Shu-Jou Chan, Xinxin Liu, An-Chi Wei, Ru-In Jian, Kuan-Wei Huang, Yaw-Dong Lang, Jou-Ho Shih, Chun-Chieh Liao, Chiu-Lin Luan, Yu-Tung Kao, Shang-Yin Chiang, Pei-Wen Hsiao, Yuh-Shan Jou, Yunching Chen, Ruey-Hwa Chen
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-24 (2022)
Abstract Background Metastasis and chemoresistance are major culprits of cancer mortality, but factors contributing to these processes are incompletely understood. Methods Bioinformatics methods were used to identify the relations of Smyca expression
Externí odkaz:
https://doaj.org/article/a8ced82434e347259ea6f0bb87743738
Autor:
Yu-Hsuan Chen, Tzu-Yu Huang, Yu-Tung Lin, Shu-Yu Lin, Wen-Hsin Li, Hsiang-Jung Hsiao, Ruei-Liang Yan, Hong-Wen Tang, Zhao-Qing Shen, Guang-Chao Chen, Kuen-Phon Wu, Ting-Fen Tsai, Ruey-Hwa Chen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Autophagy and the ubiquitin–proteasome system (UPS) are cellular quality control processes, but their coordination remains unclear. Here, the authors show that branched ubiquitination of VPS34 functions as a switch between UPS and autophagy and has
Externí odkaz:
https://doaj.org/article/48717331846c4d5699d2e8a3c33c5192
Autor:
Yaw-Dong Lang, Hsin-Yi Chen, Chun-Ming Ho, Jou-Ho Shih, En-Chi Hsu, Roger Shen, Yu-Ching Lee, Jyun-Wei Chen, Cheng-Yen Wu, Hsi-Wen Yeh, Ruey-Hwa Chen, Yuh-Shan Jou
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
PSPC1 has a critical role in promoting EMT and metastasis. Here, the authors demonstrate that PSPC1 is the contextual determinant of the oncogenic switch of PTK6/β-catenin subcellular localizations to drive metastasis of hepatocellular carcinoma cel
Externí odkaz:
https://doaj.org/article/6ae4243b31584b1da82d9909f2146f87
Autor:
Yu-Hsuan Chen, Ruey-Hwa Chen
Publikováno v:
Molecular & Cellular Oncology, Vol 8, Iss 3 (2021)
Ubiquitin-proteasome system and autophagy are the two major recycling processes. Our recent work uncovers a K29/K48 branched ubiquitination on the phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3KC3, best known as VPS34). This ubiquitinati
Externí odkaz:
https://doaj.org/article/47dabfef38e04489b6258a86e6c10b8a