Zobrazeno 1 - 10
of 1 107
pro vyhledávání: '"Ruepp A"'
Autor:
Yannick Weyer, Sinead I. Schwabl, Xuechen Tang, Astha Purwar, Konstantin Siegmann, Angela Ruepp, Theresia Dunzendorfer-Matt, Michael A. Widerin, Veronika Niedrist, Noa J. M. Mutsters, Maria G. Tettamanti, Sabine Weys, Bettina Sarg, Leopold Kremser, Klaus R. Liedl, Oliver Schmidt, David Teis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The Golgi apparatus is essential for protein sorting, yet its quality control mechanisms are poorly understood. Here we show that the Dsc ubiquitin ligase complex uses its rhomboid pseudo-protease subunit, Dsc2, to assess the hydrophobic len
Externí odkaz:
https://doaj.org/article/a3ea189c8f004297a4061ede608ffc48
Autor:
Seung Chan Kim, Scott J. Mitchell, Seema Qamar, Daniel J. Whitcomb, Marc-David Ruepp, Peter St George-Hyslop, Kwangwook Cho
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract The hypomethylation of fused in sarcoma (FUS) in frontotemporal lobar degeneration promotes the formation of irreversible condensates of FUS. However, the mechanisms by which these hypomethylated FUS condensates cause neuronal dysfunction ar
Externí odkaz:
https://doaj.org/article/f1d094e7bd984d60b4f09d9494f5578d
Autor:
Sébastien Campagne, Daniel Jutzi, Florian Malard, Maja Matoga, Ksenija Romane, Miki Feldmuller, Martino Colombo, Marc-David Ruepp, Frédéric H-T. Allain
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Pharmacologic depletion of RNA-binding motif 39 (RBM39) using aryl sulfonamides represents a promising anti-cancer therapy but requires high levels of the adaptor protein DCAF15. Consequently, novel approaches to deplete RBM39 in an DCAF15-i
Externí odkaz:
https://doaj.org/article/79b7174732b448a7b9de0ce1ce1bf801
Publikováno v:
In Computer Networks April 2024 243
Autor:
Mengya Shi, Siyu Han, Kristin Klier, Gisela Fobo, Corinna Montrone, Shixiang Yu, Makoto Harada, Ann-Kristin Henning, Nele Friedrich, Martin Bahls, Marcus Dörr, Matthias Nauck, Henry Völzke, Georg Homuth, Hans J. Grabe, Cornelia Prehn, Jerzy Adamski, Karsten Suhre, Wolfgang Rathmann, Andreas Ruepp, Johannes Hertel, Annette Peters, Rui Wang-Sattler
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Background Metabolic Syndrome (MetS) is characterized by risk factors such as abdominal obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol (HDL-C), hypertension, and hyperglycemia, which contribute to the development of
Externí odkaz:
https://doaj.org/article/ae77aba3a99a49d3bf080ee8cff128b9
Autor:
María Gordillo-Marañón, Gianmario Candore, Marta López-Fauqued, Katerina-Christina Deli, Loris Piccolo, Paolo Alcini, Tom Paternoster-Howe, Irene Rager, Robin Ruepp, Menno van der Elst
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionPeriodic Safety Update Reports (PSURs) are a key pharmacovigilance tool for the continuous evaluation of the benefit–risk balance of a medicinal product in the post-authorisation phase. The PSUR submission frequency for authorised activ
Externí odkaz:
https://doaj.org/article/0a377b317bc14f79a773c8fe17459be0
Path-loss modelling in deep-indoor scenarios is a difficult task. On one hand, the theoretical formulae solely dependent on transmitter-receiver distance are too simple; on the other hand, discovering all significant factors affecting the loss of sig
Externí odkaz:
http://arxiv.org/abs/2006.00880
Autor:
Beltran-Lobo, Paula, Hughes, Martina M., Troakes, Claire, Croft, Cara L., Rupawala, Huzefa, Jutzi, Daniel, Ruepp, Marc-David, Jimenez-Sanchez, Maria, Perkinton, Michael S., Kassiou, Michael, Golde, Todd E., Hanger, Diane P., Verkhratsky, Alexei, Perez-Nievas, Beatriz G., Noble, Wendy
Publikováno v:
In Brain Behavior and Immunity November 2023 114:414-429
Autor:
Stahel, Rolf, Hiltbrunner, Anita, Kammler, Rosita, Marti, Nesa, Ruepp, Barbara, Dafni, Urania, Tsourti, Zoi, Zygoura, Panagiota, Vervita, Katerina, Dimopoulou, Georgia, Andriakopoulou, Charitini, Stavrou, Androniki, Rüschoff, Jan H., Haberecker, Martina, Dettwiler, Susanne, Prutek, Fabiola, Mittmann, Christiane, Opitz, Isabelle, Vrugt, Bart, Friess, Martina, Matter, Alessandra, Spichiger-Häusermann, Chloé, Kirschner, Michaela B., Felley-Bosco, Emanuela, Baas, Paul, Monkhorst, Kim, Nackaerts, Kristiaan, Verbeken, Eric, Weynand, Birgit, Nafteux, Philippe, Moons, Johnny, Peeters, Liesbet, Ampollini, Luca, Tiseo, Marcello, Silini, Enrico Maria, Gnetti, Letizia, Carbognani, Paolo, de Perrot, Marc, Bavaghar-Zaeimi, Fatemeh, Brcic, Luka, Samarzija, Miroslav, Seiwerth, Sven, Jakopovic, Marko, Nadal, Ernest, Cardenal, Felipe, Llatjos, Roger, Lorente, Susana, Syrigos, Konstantinos, Vamvakaris, Ioannis, Tsimpoukis, Sotirios, Boura, Paraskevi, Gray, Steven G., Finn, Stephen P., Nur, Mutaz Mohammed, Baird, Anne-Marie, Barr, Martin P., Cuffe, Sinead, Gately, Kathy, Aerts, Joachim, Thüsen, Jan von der, Bille, Andrea, Passani, Stefano, Brunelli, Alessandro, Curioni-Fontecedro, Alessandra, von der Thüsen, Jan, Kammler, Roswitha, Peters, Solange, Stahel, Rolf A., Falcoz, Pierre-Emmanuel
Publikováno v:
In Journal of Thoracic Oncology September 2023 18(9):1233-1247
Autor:
Strack Normann, Schmidt Thorsten, Oesterheld Matthias, Blöchl Florian, Smialowski Pawel, Geissler Bernd, Pagel Philipp, Kirschner Andreas, Hildebrand Andrea, Althammer Sonja, Wong Philip, Theis Fabian J, Ruepp Andreas, Frishman Dmitrij
Publikováno v:
BMC Genomics, Vol 9, Iss 1, p 629 (2008)
Abstract Background We have recently released a comprehensive, manually curated database of mammalian protein complexes called CORUM. Combining CORUM with other resources, we assembled a dataset of over 2700 mammalian complexes. The availability of a
Externí odkaz:
https://doaj.org/article/e60b1b24051b48b58e2158d28ad119ba