Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ruei‐Yu He"'
Engineered droplet-forming peptide as photocontrollable phase modulator for fused in sarcoma protein
Autor:
Hao-Yu Chuang, Ruei-Yu He, Yung-An Huang, Wan-Ting Hsu, Ya-Jen Cheng, Zheng-Rong Guo, Niaz Wali, Ing-Shouh Hwang, Jiun-Jie Shie, Joseph Jen-Tse Huang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The assembly and disassembly of biomolecular condensates are crucial for the subcellular compartmentalization of biomolecules in the control of cellular reactions. Recently, a correlation has been discovered between the phase transition of c
Externí odkaz:
https://doaj.org/article/23d275a15afb4371887d4b92b23eb281
Autor:
Hao-Yu Chuang, Ruei-Yu He, Yung-An Huang, Wan-Ting Hsu, Ya-Jen Cheng, Zheng-Rong Guo, Niaz Wali, Ing-Shouh Hwang, Jiun-Jie Shie, Joseph Jen-Tse Huang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/cf2246578dee4fe7a07a262482fda75d
Autor:
Yu-Ling Tseng, Po-Chao Lu, Chi-Chang Lee, Ruei-Yu He, Yung-An Huang, Yin-Chen Tseng, Ting-Jen Rachel Cheng, Joseph Jen-Tse Huang, Jim-Min Fang
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-21 (2023)
Abstract Background Amyotrophic lateral sclerosis (ALS) associated with TAR DNA-binding protein 43 (TDP-43) aggregation has been considered as a lethal and progressive motor neuron disease. Recent studies have shown that both C-terminal TDP-43 (C-TDP
Externí odkaz:
https://doaj.org/article/461b394b4545469c870b07ecbc2ec3c9
Autor:
Hung-Ming Chien, Ruei-Yu He, Chi-Chang Lee, Yung-An Huang, I-Ju Hung, Kai-Ting Hou, Jye-Chian Hsiao, Po-Chao Lu, Diksha Agnihotri, Eric Hwang, Joseph Jen-Tse Huang
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-13 (2021)
Glycine-alanine dipeptide repeats produced by the C9orf72 gene are proposed to cause neurotoxicity in related diseases, but is challenging to study experimentally. Here a photolabile cell-penetrating peptide allows superresolution imaging of the dist
Externí odkaz:
https://doaj.org/article/d0d8eaa2f8954cce873fb107a77d365a
Autor:
Ruei‐Yu He, Xiang‐Me Lai, Chia‐Sui Sun, Te‐Shien Kung, Jhu‐Ying Hong, Yu‐Song Jheng, Wei‐Neng Liao, Jen‐Kun Chen, Yung‐Feng Liao, Pang‐Hsien Tu, Joseph Jen‐Tse Huang
Publikováno v:
Advanced Science, Vol 7, Iss 2, Pp n/a-n/a (2020)
Abstract Finding an effective therapeutic regimen is an urgent demand for various neurodegenerative disorders including Huntington's disease (HD). For the difficulties in observing the dynamic aggregation and oligomerization process of mutant Hunting
Externí odkaz:
https://doaj.org/article/ea4bbab767c443acb71235cffdefc1b7
Autor:
Bryan Po-Wen Chen, Ruei-Yu He, Hung-Ming Chien, Chi-Chang Lee, Hsiao-Han Chuang, Chao-Ping Hsu, Jerry C. C. Chan, Joseph Jen-Tse Huang
Publikováno v:
ACS Applied Nano Materials. 5:1734-1739
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9447a2514d15a3b1b095a1302c54b8a
https://doi.org/10.1021/acsanm.1c04004
https://doi.org/10.1021/acsanm.1c04004
Autor:
Devi Wahyuningtyas, Wen-Hao Chen, Ruei-Yu He, Yung-An Huang, Chia-Kang Tsao, Yu-Jung He, Chu-Yi Yu, Po-Chao Lu, Yu-Cai Chen, Sheng-Hann Wang, Ka Chon Ng, Bryan Po-Wen Chen, Pei-Kuen Wei, Jiun-Jie Shie, Chun-Hong Kuo, Y. Henry Sun, Joseph Jen-Tse Huang
Publikováno v:
ACS Applied Materials & Interfaces. 13:60894-60906
Huntington's disease (HD) belongs to protein misfolding disorders associated with polyglutamine (polyQ)-rich mutant huntingtin (mHtt) protein inclusions. Currently, it is indicated that the aggregation of polyQ-rich mHtt participates in neuronal toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80b8d4b82b79663531f9fe4bcddc336
https://doi.org/10.1021/acsami.1c18754
https://doi.org/10.1021/acsami.1c18754
Publikováno v:
Bioengineering, Vol 2, Iss 3, Pp 139-159 (2015)
Haptotaxis, i.e., cell migration in response to adhesive gradients, has been previously implicated in cancer metastasis. A better understanding of cell migration dynamics and their regulation could ultimately lead to new drug targets, especially for
Externí odkaz:
https://doaj.org/article/f0fe46793f3b4e028a33cbdc607840b6
Autor:
Chia-Sui Sun, Cindy Yu-Hsiang Wang, Bryan Po-Wen Chen, Ruei-Yu He, Gerard Chun-Hao Liu, Chih-Hsien Wang, Wenlung Chen, Yijuang Chern, Joseph Jen-Tse Huang
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103644 (2014)
TAR DNA-binding protein (TDP-43) was identified as the major ubiquitinated component deposited in the inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) in 2006. L
Externí odkaz:
https://doaj.org/article/2eb737dcff63473482e9c3c1931e670b
Autor:
Hung-Ming Chien, Ruei-Yu He, Chi-Chang Lee, Yung-An Huang, I-Ju Hung, Kai-Ting Hou, Jye-Chian Hsiao, Po-Chao Lu, Diksha Agnihotri, Eric Hwang, Jen-Tse Huang
Dipeptide repeats (DPRs) translated from the mutated C9orf72 gene have recently been correlated with amyotrophic lateral sclerosis (ALS). Within these DPRs, the most abundant glycine-alanine (GA) DPRs form insoluble inclusions in C9orf72-ALS patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee9cf03a4811d5abdce4aca90a9892fa
https://doi.org/10.21203/rs.3.rs-209180/v1
https://doi.org/10.21203/rs.3.rs-209180/v1
