Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rudy Leibel"'
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59114 (2013)
Treating obesity has proven to be an intractable challenge, in part, due to the difficulty of maintaining reduced weight. In our previous studies of in-patient obese subjects, we have shown that leptin repletion following a 10% or greater weight loss
Externí odkaz:
https://doaj.org/article/f9b1e9bb115e40d5b3fb6051bed4b96a
Autor:
M. C. De Rosa, Claudia A. Doege, Rudy Leibel, Stephen H. Tsang, Linshan Shang, Dieter Egli, Damian J. Williams, Liheng Wang, Lina Sui, George Stratigopoulos, Lisa Cole Burnett, Robin Goland, Yang Liu, Deyou Zheng, Sharon L. Wardlaw, Sunil K Panigrahi, Charles A. LeDuc, Hannah J. Glover
Bardet-Biedl Syndrome (BBS) is a rare autosomal recessive disorder caused by mutations in genes encoding components of the primary cilium and characterized by hyperphagic obesity. We developed a cellular model of BBS using induced pluripotent stem ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b1449fd25ca3636f71256bcffeab4e5
https://doi.org/10.1101/2020.10.29.359851
https://doi.org/10.1101/2020.10.29.359851
Autor:
Ilene Fennoy, Rudy Leibel, Marisa Censani, Liyong Deng, Jeffrey L. Zitsman, Sharon E. Oberfield, Wendy K. Chung, Donald J. McMahon, Rushika Conroy
Publikováno v:
Obesity (Silver Spring, Md.)
Objective To determine the frequency of Melanocortin4 Receptor (MC4R) mutations in morbidly obese adolescents undergoing bariatric surgery and compare weight loss outcomes in patients with and without mutations. Design and Methods In this prospective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f91ef1a77c14e4042c6cb0804860a85
https://doi.org/10.1002/oby.20511
https://doi.org/10.1002/oby.20511
Autor:
Hiroshi Mitsumoto, Kevin Eggan, Genevieve Saphier, Kathy K. Niakan, Rudy Leibel, Laurin M. Weisenthal, Kit T. Rodolfa, John T. Dimos, Robin Goland, Wendy K. Chung, Christopher E. Henderson, Hynek Wichterle, Gist F. Croft
Publikováno v:
Science. 321:1218-1221
The generation of pluripotent stem cells from an individual patient would enable the large-scale production of the cell types affected by that patient's disease. These cells could in turn be used for disease modeling, drug discovery, and eventually a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf72e2a15b3bda5d5d4eb5ab9dd50bc
https://doi.org/10.1126/science.1158799
https://doi.org/10.1126/science.1158799
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e59114 (2013)
PLoS ONE, Vol 8, Iss 3, p e59114 (2013)
Treating obesity has proven to be an intractable challenge, in part, due to the difficulty of maintaining reduced weight. In our previous studies of in-patient obese subjects, we have shown that leptin repletion following a 10% or greater weight loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825073cbd9fb958f3e04ea83077884f9
https://pubmed.ncbi.nlm.nih.gov/23555620
https://pubmed.ncbi.nlm.nih.gov/23555620