Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Rudy J Valentine"'
Autor:
Hyeyoon Eo, Rudy J Valentine
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
In obesity, plasma free fatty acids (FFAs) levels are elevated due to enlarged adipose tissue mass. Saturated fatty acids can induce prolonged ER stress and insulin resistance. Double-stranded RNA-dependent Protein Kinase (PKR) is activated under str
Externí odkaz:
https://doaj.org/article/e0dc1df875a042b495d94801de94211f
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244795 (2021)
BackgroundImpaired perfusion indices signal potential microvascular dysfunction preceding atherosclerosis and other cardiometabolic pathologies. Post-occlusive reactive hyperemia (PORH), a vasodilatory response following a mechanically induced ischem
Externí odkaz:
https://doaj.org/article/8819d978fce747ba83eb7cad27bedcf2
Autor:
Joe L Webb, Amanda E Bries, Brooke Vogel, Claudia Carrillo, Lily Harvison, Timothy A Day, Michael J Kimber, Rudy J Valentine, Matthew J Rowling, Stephanie Clark, Elizabeth M McNeill, Kevin L Schalinske
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0240885 (2020)
Nutrigenomic evidence supports the idea that Type 2 Diabetes Mellitus (T2DM) arises due to the interactions between the transcriptome, individual genetic profiles, lifestyle, and diet. Since eggs are a nutrient dense food containing bioactive ingredi
Externí odkaz:
https://doaj.org/article/6afb54eea5b74f8d8ee5202d2c782d41
Autor:
Kimberly A Coughlan, Thomas W Balon, Rudy J Valentine, Robert Petrocelli, Vera Schultz, Amanda Brandon, Gregory J Cooney, Edward W Kraegen, Neil B Ruderman, Asish K Saha
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127388 (2015)
We have previously shown that incubation for 1h with excess glucose or leucine causes insulin resistance in rat extensor digitorum longus (EDL) muscle by inhibiting AMP-activated protein kinase (AMPK). To examine the events that precede and follow th
Externí odkaz:
https://doaj.org/article/77dc1e82d919441083a9ad124737ee02
Autor:
Carter H Reed, Anna C. Tystahl, Hyeyoon Eo, Trevor J. Buhr, Ella E. Bauer, Ji Heun Lee, Peter J. Clark, Rudy J. Valentine
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 527 (2024)
Adverse experiences (e.g., acute stress) and alcohol misuse can both impair skeletal muscle homeostasis, resulting in reduced protein synthesis and greater protein breakdown. Exposure to acute stress is a significant risk factor for engaging in alcoh
Externí odkaz:
https://doaj.org/article/df322170af444bfc9c68ca2bbaf0cc0f
Autor:
Trevor J. Buhr, Carter H. Reed, Olivia M. Wee, Ji Heun Lee, Li-Lian Yuan, Monika Fleshner, Rudy J. Valentine, Peter J. Clark
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
IntroductionSedentary lifestyles have reached epidemic proportions world-wide. A growing body of literature suggests that exposures to adverse experiences (e.g., psychological traumas) are a significant risk factor for the development of physically i
Externí odkaz:
https://doaj.org/article/ca524652b9c54f1bbb6dd629c859a954
Autor:
Swathy Krishna, Hannah R. Spaulding, James E. Koltes, John C. Quindry, Rudy J. Valentine, Joshua T. Selsby
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Duchenne muscular dystrophy (DMD) is a progressive muscle disease that results in muscle wasting, wheelchair dependence, and eventual death due to cardiac and respiratory complications. In addition to muscle fragility, dystrophin deficiency also resu
Externí odkaz:
https://doaj.org/article/e24a80efa87547af8ced1ecc2e6fb343
Autor:
Corey M. Summers, Rudy J. Valentine
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
Autophagy is a major intracellular degradation process that is essential for the clearance of unnecessary proteins/organelles and the maintenance of cellular homeostasis. The inhibition of autophagy results in cellular consequences associated with ma
Externí odkaz:
https://doaj.org/article/fe29611550504b908f78a827e9d8fa03
Publikováno v:
Medicine & Science in Sports & Exercise. 54:1288-1299
Chronic exercise training is known to induce metabolic changes, but whether these adaptations extend to lymphocytes and how this may affect immune function remains largely unknown. This study was conducted to determine the extent to which mitochondri
Autor:
Corey M. Summers, Rudy J. Valentine
Publikováno v:
Cell Biochemistry and Biophysics. 80:367-373