Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rudranil, De"'
Autor:
Subhashis Debsharma, Saikat Pramanik, Samik Bindu, Somnath Mazumder, Troyee Das, Uttam Pal, Debanjan Saha, Rudranil De, Shiladitya Nag, Chinmoy Banerjee, Nakul Chandra Maiti, Zhumur Ghosh, Uday Bandyopadhyay
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109384- (2024)
Summary: Gastric cancer (GC) is a deadly malignancy that demands effective therapeutic intervention capitalizing unique drug target/s. Here, we report that indomethacin, a cyclooxygenase non-selective non-steroidal anti-inflammatory drug, arrests GC
Externí odkaz:
https://doaj.org/article/f474bf5178804b12befd7ffeeced126b
Autor:
Shiladitya Nag, Chinmoy Banerjee, Manish Goyal, Asim Azhar Siddiqui, Debanjan Saha, Somnath Mazumder, Subhashis Debsharma, Saikat Pramanik, Shubhra Jyoti Saha, Rudranil De, Uday Bandyopadhyay
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109467- (2024)
Summary: Alba domain proteins, owing to their functional plasticity, play a significant role in organisms. Here, we report an intrinsic DNase activity of PfAlba6 from Plasmodium falciparum, an etiological agent responsible for human malignant malaria
Externí odkaz:
https://doaj.org/article/5007f20a1e144d17aafe1713d94a44de
Autor:
Subhashis Debsharma, Saikat Pramanik, Samik Bindu, Somnath Mazumder, Troyee Das, Debanjan Saha, Rudranil De, Shiladitya Nag, Chinmoy Banerjee, Asim Azhar Siddiqui, Zhumur Ghosh, Uday Bandyopadhyay
Publikováno v:
British Journal of Pharmacology.
Autor:
Somnath Mazumder, Samik Bindu, Rudranil De, Subhashis Debsharma, Saikat Pramanik, Uday Bandyopadhyay
Publikováno v:
Life sciences. 305
Gastroduodenal inflammation and ulcerative injuries are increasing due to expanding socio-economic stress, unhealthy food habits-lifestyle, smoking, alcoholism and usage of medicines like non-steroidal anti-inflammatory drugs. In fact, gastrointestin
Publikováno v:
Molecular and cellular biochemistry.
SARS-CoV-2 is a positive-strand RNA virus that infects humans through the nasopharyngeal and oral route causing COVID-19. Scientists left no stone unturned to explore a targetable key player in COVID-19 pathogenesis against which therapeutic interven
Publikováno v:
Cell Biology and Toxicology. 37:333-366
Mitochondria are double membrane-bound cellular work-horses constantly functioning to regulate vital aspects of cellular metabolism, bioenergetics, proliferation and death. Biogenesis, homeostasis and regulated turnover of mitochondria are stringentl
Publikováno v:
Biochemical Pharmacology. 208:115369
Macrophages are specialized immune cells, which have the capacity to phagocytize and destroy the target cells, including tumor cells. Some macrophages, however on their way to devour the cancer cells undergo a change due to a complex set of signaling
Publikováno v:
Cell biology and toxicology. 37(3)
Mitochondria are double membrane-bound cellular work-horses constantly functioning to regulate vital aspects of cellular metabolism, bioenergetics, proliferation and death. Biogenesis, homeostasis and regulated turnover of mitochondria are stringentl
Autor:
Chinmoy Banerjee, Asim Azhar Siddiqui, Rudranil De, Shiladitya Nag, Somnath Mazumder, Uday Bandyopadhyay, Souvik Sarkar, Subhashis Debsharma, Saikat Pramanik, Debanjan Saha, Shubhra Jyoti Saha
Publikováno v:
Journal of Biological Chemistry. 293:19740-19760
The indispensable role of macrophage migration inhibitory factor (MIF) in cancer cell proliferation is unambiguous, although which specific roles the cytokine plays to block apoptosis by preserving cell growth is still obscure. Using different cancer
Autor:
Shubhra Jyoti Saha, Chinmoy Banerjee, Uday Bandyopadhyay, Subhashis Debsharma, Shiladitya Nag, Somnath Mazumder, Rudranil De, Saikat Pramanik, Debanjan Saha, Asim Azhar Siddiqui
Publikováno v:
ACS Infectious Diseases. 5:63-73
The rapid emergence of resistance against frontline antimalarial drugs essentially warrants the identification of new-generation antimalarials. Here, we describe the synthesis of ( E)-2-isopropyl-5-methyl-4-((2-(pyridin-4-yl)hydrazono)methyl)phenol (