Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rudradip Das"'
Publikováno v:
Results in Chemistry, Vol 5, Iss , Pp 100950- (2023)
Tyrosine kinases are significant mediators of the signaling cascade that play vital role in various biological processes. The involvement of tyrosine kinases in regulating and functioning various metabolic pathways in the body has encouraged scientis
Externí odkaz:
https://doaj.org/article/3ec7fc0beed440bc92578f4def80187a
Autor:
Astha Gupta, Rudradip Das, Ambika Chamoli, Asmita Choithramani, Hansal Kumar, Sagarkumar Patel, Datta Khude, Gourav Bothra, Khushal Wangdale, Moumita Ghosh Chowdhury, Rajeshwari Rathod, Amit Mandoli, Amit Shard
Publikováno v:
Organometallics. 41:2365-2378
Publikováno v:
Current Drug Targets. 24
Abstract: Pyruvate kinase M2 (PKM2) has surfaced as a potential target for anti-cancer therapy. PKM2 is known to be overexpressed in the tumor cells and is a critical metabolic conduit in supplying the augmented bioenergetic demands of the recalcitra
A molecular perspective for the use of type IV tyrosine kinase inhibitors as anticancer therapeutics
Publikováno v:
Drug Discovery Today. 27:808-821
Tyrosine kinases are enzymes that can transfer a phosphate group from ATP to a specific protein tyrosine, serine or threonine residue within a cell, operating as a switch that can turn 'on' and 'off' causing different physiological alterations in the
Autor:
Arnab Chowdhury, Bhaskar Dewangan, Kiran Kalia, Santosh Kumar Behera, Amit Shard, Bichismita Sahu, Rudradip Das, Tanay Dalvi
Publikováno v:
Current Computer-Aided Drug Design. 18:26-40
Introduction: The outburst of the novel coronavirus COVID-19, at the end of December 2019 has turned itself into a pandemic taking a heavy toll on human lives. The causal agent being SARS-CoV-2, a member of the long-known Coronaviridae family, is a p
Autor:
Moumita Ghosh Chowdhury, Rudradip Das, Het Vyas, Tejal Sasane, Omprakash Mori, Sayali Kamble, Sagarkumar Patel, Amit Shard
Publikováno v:
ChemistrySelect. 7
Autor:
Hansal Kumar, Amit Shard, Datta Khude, Asmita Choithramani, Astha Gupta, Rudradip Das, Gourav Bothra
Publikováno v:
ChemistrySelect. 6:5807-5837
Autor:
Deep Rohan Chatterjee, Saumya Kapoor, Meenakshi Jain, Rudradip Das, Moumita Ghosh Chowdhury, Amit Shard
Publikováno v:
Drug discovery today. 28(1)
The dawn of targeted degradation using proteolysis-targeting chimeras (PROTACs) against recalcitrant proteins has prompted numerous efforts to develop complementary drugs. Although many of these are specifically directed against undruggable proteins,
Autor:
Ashish Jogpethe, Tarang Jadav, Niraj Rajput, Amit Kumar Sahu, Rudradip Das, Astha Gupta, Amit Shard, Pinaki Sengupta
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1210
Pyrazolopyrimidine ring present in various approved drugs is reported to target the tyrosine kinase receptor. A new pyrazolopyrimidine ferrocene derivative, which targets tumor pyruvate kinase M2 showed an impressive antiproliferative profile against
Autor:
Alok Jain, Jyoti Rani, Bhavinkumar Gayakvad, Bichismita Sahu, Rudradip Das, Suchita Dattatray Shinde
Publikováno v:
ACS applied bio materials. 3(9)
Because of their commanding properties, ultrashort and short peptides are gaining significance as viable candidates for molecular self-assembly, which is a naturally inspired approach for developing supramolecular structures and can be used to design