Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rudolf Wachtel"'
Autor:
Sergey Savitskiy, Rudolf Wachtel, Danial Pourjafar-Dehkordi, Hyun-Seo Kang, Vanessa Trauschke, Don C. Lamb, Michael Sattler, Martin Zacharias, Aymelt Itzen
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101940- (2021)
Summary: Rab GTPases are central regulators of intracellular vesicular trafficking. They are frequently targeted by bacterial pathogens through post-translational modifications. Salmonella typhimurium secretes the cysteine protease GtgE during infect
Externí odkaz:
https://doaj.org/article/54b015bc474e49a788f63f6a048963d6
Autor:
Rudolf Wachtel, Bastian Bräuning, Sophie L. Mader, Felix Ecker, Ville R. I. Kaila, Michael Groll, Aymelt Itzen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The bacterial protease GtgE is involved in the establishment of Salmonellosis. Here the authors provide a structural and biochemical analysis of GtgE that sheds light on the molecular mechanisms of reprogramming infected host cells via site-specific
Externí odkaz:
https://doaj.org/article/b1737a5a57314d0189c7e7ac298e8846
Autor:
Vanessa Trauschke, Don C. Lamb, Michael Sattler, Sergey Savitskiy, Hyun-Seo Kang, Martin Zacharias, Aymelt Itzen, Danial Pourjafar-Dehkordi, Rudolf Wachtel
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101940-(2021)
iScience 24:101940 (2021)
iScience
iScience 24:101940 (2021)
iScience
Summary Rab GTPases are central regulators of intracellular vesicular trafficking. They are frequently targeted by bacterial pathogens through post-translational modifications. Salmonella typhimurium secretes the cysteine protease GtgE during infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a797bffede826e7bd792e4760d2eac
https://doi.org/10.1016/j.isci.2020.101940
https://doi.org/10.1016/j.isci.2020.101940
Autor:
Aymelt Itzen, Sophie L. Mader, Bastian Bräuning, Ville R. I. Kaila, Michael Groll, Rudolf Wachtel, Felix Ecker
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Salmonella infections require the delivery of bacterial effectors into the host cell that alter the regulation of host defense mechanisms. The secreted cysteine protease GtgE from S. Typhimurium manipulates vesicular trafficking by modifying the Rab3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6803438a0ca933a316314b4fb5f30ed7
https://pubmed.ncbi.nlm.nih.gov/29298974
https://pubmed.ncbi.nlm.nih.gov/29298974
Publikováno v:
Angewandte Chemie (International ed. in English)
Nonribosomal peptide synthetases (NRPSs) are multifunctional enzymes that produce a wide array of bioactive peptides. Here we show that a single tryptophan-to-serine mutation in phenylalanine-specific NRPS adenylation domains enables the efficient ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240bca54031d878a20cd9bc626c8c01d
https://doi.org/10.1002/anie.201405281
https://doi.org/10.1002/anie.201405281
Autor:
Anja List, Ferdinand Alte, Evelyn Zeiler, Marcin Drag, Rudolf Wachtel, Malte Gersch, Michael Groll, Stephan A. Sieber, Marcin Poreba
Publikováno v:
Proceedings of the National Academy of Sciences. 110:11302-11307
Caseinolytic proteases (ClpPs) are large oligomeric protein complexes that contribute to cell homeostasis as well as virulence regulation in bacteria. Although most organisms possess a single ClpP protein, some organisms encode two or more ClpP isofo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db9dd37f80c1c4202d3015d2b47dbff
https://doi.org/10.1073/pnas.1219125110
https://doi.org/10.1073/pnas.1219125110
Autor:
Christian Devigny, Serena Cuboni, Jan M. Deussing, Felix Hausch, Katharine J Webb, Christoph P. Mauch, Francisco Perez-Balderas, Rudolf Wachtel, B. Hoogeland
Publikováno v:
Journal of the American Chemical Society. 133:8927-8933
The 41-amino acid peptide corticotropin releasing factor (CRF) is a major modulator of the mammalian stress response. Upon stressful stimuli, it binds to the corticotropin releasing factor receptor 1 (CRF(1)R), a typical member of the class-B G-prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee81e8565d398eeb8702d67bc00e578c
https://doi.org/10.1021/ja200160s
https://doi.org/10.1021/ja200160s
Autor:
Devigny, Christian, Perez-Balderas, Francisco, Hoogeland, Bastiaan, Cuboni, Serena, Rudolf Wachtel, Mauch, Christoph P., Webb, Katharine J., Deussing, Jan M., Hausch, Felix
Publikováno v:
Journal of the American Chemical Society; 6/15/2011, Vol. 133 Issue 23, p8927-8933, 7p