Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Rudolf Schubert"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7140 (2024)
It has been reported that, in the spontaneously hypertensive rat (SHR) model of hypertension, different components of the G-protein/adenylate cyclase (AC)/Calcium-activated potassium channel of high conductance (BK) channel signaling pathway are alte
Externí odkaz:
https://doaj.org/article/91fead34262f4e34a39d24883ab6b3f4
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
The study of the mechanisms of regulation of vascular tone is an urgent task of modern science, since diseases of the cardiovascular system remain the main cause of reduction in the quality of life and mortality of the population. Myography (isometri
Externí odkaz:
https://doaj.org/article/de2ca02f279847efaa54f1bf308fc7e2
Autor:
Kristina Här, Natalia N. Lysenko, Daniela Dimitrova, Torsten Schlüter, Olga Zavaritskaya, Andrej G. Kamkin, Mitko Mladenov, Olaf Grisk, Ralf Köhler, Hristo Gagov, Rudolf Schubert
Publikováno v:
Cells, Vol 12, Iss 15, p 1989 (2023)
Vascular smooth muscle voltage-gated potassium (Kv) channels have been proposed to contribute to myogenic autoregulation. Surprisingly, in initial experiments, we observed that the Kv2 channel inhibitor stromatoxin induced vasomotion without affectin
Externí odkaz:
https://doaj.org/article/3c4f3307479b4d44aabaea38ba405f9c
Autor:
Anastasia A. Shvetsova, Varvara S. Lazarenko, Dina K. Gaynullina, Olga S. Tarasova, Rudolf Schubert
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Aim: TASK-1 channels are established regulators of pulmonary artery tone but their contribution to the regulation of vascular tone in systemic arteries is poorly understood. We tested the hypothesis that TASK-1 channel functional impact differs among
Externí odkaz:
https://doaj.org/article/c1f75bd81a034e6d918e4a1b4db37fd6
Autor:
Iliyana Sazdova, Milena Keremidarska-Markova, Mariela Chichova, Blagoy Uzunov, Georgi Nikolaev, Mitko Mladenov, Rudolf Schubert, Maya Stoyneva-Gärtner, Hristo S. Gagov
Publikováno v:
Journal of Toxicology, Vol 2022 (2022)
Cyanotoxins (CTs) are a large and diverse group of toxins produced by the peculiar photosynthetic prokaryotes of the domain Cyanoprokaryota. Toxin-producing aquatic cyanoprokaryotes can develop in mass, causing “water blooms” or “cyanoblooms,
Externí odkaz:
https://doaj.org/article/9828bf8789704598bc161a7628343fbe
Autor:
Danfeng Zhang, Bernhard M. Krause, Hans-Günther Schmalz, Paulus Wohlfart, Benito A. Yard, Rudolf Schubert
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Although the vasoactive properties of carbon monoxide (CO) have been extensively studied, the mechanism by which CO mediates vasodilation is not completely understood. Through-out published studies on CO mediated vasodilation there is inconsistency o
Externí odkaz:
https://doaj.org/article/f86381ab7d1e4e40986c3c53dcb6af13
Autor:
Dina K. Gaynullina, Olga S. Tarasova, Anastasia A. Shvetsova, Anna A. Borzykh, Rudolf Schubert
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 5987 (2022)
The activity of many vasomotor signaling pathways strongly depends on extracellular/intracellular pH. Nitric oxide (NO) is one of the most important vasodilators produced by the endothelium. In this review, we present evidence that in most vascular b
Externí odkaz:
https://doaj.org/article/0f4f0196ac6a4ee7a7969154753135d3
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
BackgroundVoltage-gated potassium (Kv) channels, especially Kv7 channels, are major potassium channels identified in vascular smooth muscle cells with a great, albeit differential functional impact in various vessels. Vascular smooth muscle Kv7 chann
Externí odkaz:
https://doaj.org/article/75effa90725b4e589aa721bb03b9ceb0
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2798 (2022)
Nitric oxide (NO) is a powerful vasodilator in different vascular beds and NO-donors are widely used in clinical practice. Early data suggested that NO and NO-donors activate vascular smooth muscle high-conductance, calcium-activated potassium channe
Externí odkaz:
https://doaj.org/article/b375d959ca7b42a890188b82caf4c94a
Autor:
Mimoza Stamenkovska, Qendrim Thaçi, Nikola Hadzi‐Petrushev, Marija Angelovski, Jane Bogdanov, Shkëlzen Reçica, Islam Kryeziu, Hristo Gagov, Vadim Mitrokhin, Andre Kamkin, Rudolf Schubert, Mitko Mladenov, Ramadan B. Sopi
Publikováno v:
Physiological Reports, Vol 8, Iss 16, Pp n/a-n/a (2020)
Abstract Background This study was undertaken to test the hypothesis that the newly synthesized curcuminoids B2BrBC and C66 supplementation will overcome hyperoxia‐induced tracheal hyperreactivity and impairment of relaxation of tracheal smooth mus
Externí odkaz:
https://doaj.org/article/08bd8701b1fc4de6992b371cb941583b