Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Rudolf Merkel"'
Autor:
Daniel Navin Olschewski, Nilufar Nazarzadeh, Felix Lange, Anna Maria Koenig, Christina Kulka, Jella-Andrea Abraham, Stefan Johannes Blaschke, Rudolf Merkel, Bernd Hoffmann, Gereon Rudolf Fink, Michael Schroeter, Maria Adele Rueger, Sabine Ulrike Vay
Publikováno v:
BMC Neuroscience, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Astrocytes are the most abundant cell type of the central nervous system and are fundamentally involved in homeostasis, neuroprotection, and synaptic plasticity. This regulatory function of astrocytes on their neighboring cells in
Externí odkaz:
https://doaj.org/article/bc674676932a4f62ab2291b14f244c50
Autor:
Matthias Rübsam, Robin Püllen, Frederik Tellkamp, Alessandra Bianco, Marc Peskoller, Wilhelm Bloch, Kathleen J. Green, Rudolf Merkel, Bernd Hoffmann, Sara A. Wickström, Carien M. Niessen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Epithelia maintain a functional barrier during tissue turnover while facing varying mechanical stress. This maintenance requires both dynamic cell rearrangements driven by actomyosin-linked intercellular adherens junctions and ability to ada
Externí odkaz:
https://doaj.org/article/49b8af49c71147bfa299ecb65e9ed353
Autor:
Stefan J. Blaschke, Nora Rautenberg, Heike Endepols, Aileen Jendro, Jens Konrad, Susan Vlachakis, Dirk Wiedermann, Michael Schroeter, Bernd Hoffmann, Rudolf Merkel, Niklas Marklund, Gereon R. Fink, Maria A. Rueger
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4837 (2024)
Concussion, caused by a rotational acceleration/deceleration injury mild enough to avoid structural brain damage, is insufficiently captured in recent preclinical models, hampering the relation of pathophysiological findings on the cellular level to
Externí odkaz:
https://doaj.org/article/45102d0498af4c43892fd4908a21925a
Autor:
Annika Gross, Biaohuan Zhou, Lisa Bewersdorf, Nicole Schwarz, Gabriel M. Schacht, Peter Boor, Konrad Hoeft, Bernd Hoffmann, Elaine Fuchs, Rafael Kramann, Rudolf Merkel, Rudolf E. Leube, Pavel Strnad
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 4, Pp 1181-1200 (2022)
Background & Aims: Desmosomes are intercellular junctions connecting keratin intermediate filaments of neighboring cells. The cadherins desmoglein 2 (Dsg2) and desmocollin 2 mediate cell–cell adhesion, whereas desmoplakin (Dsp) provides the attachm
Externí odkaz:
https://doaj.org/article/81482cea13794afab6f7928cf210e021
Autor:
Marco Hoffmann, Sven Gerlach, Christina Hoffmann, Nathalie Richter, Nils Hersch, Agnes Csiszár, Rudolf Merkel, Bernd Hoffmann
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Efficient and reliable transfer of nucleic acids for therapy applications is a major challenge. Stabilization of lipo- and polyplexes has already been successfully achieved by PEGylation. This modification reduces the interaction with serum proteins
Externí odkaz:
https://doaj.org/article/5464752b69214f02800ed8d0e0f6f161
Autor:
Lisann Esser, Ronald Springer, Georg Dreissen, Lukas Lövenich, Jens Konrad, Nico Hampe, Rudolf Merkel, Bernd Hoffmann, Erik Noetzel
Publikováno v:
Cells, Vol 12, Iss 9, p 1256 (2023)
Cell contractility regulates epithelial tissue geometry development and homeostasis. The underlying mechanobiological regulation circuits are poorly understood and experimentally challenging. We developed an elastomeric pillar cage (EPC) array to qua
Externí odkaz:
https://doaj.org/article/dfacf12566094b0d9e75214a25ca83ca
Autor:
Marco Hoffmann, Sven Gerlach, Masanari Takamiya, Samar Tarazi, Nils Hersch, Agnes Csiszár, Ronald Springer, Georg Dreissen, Hanno Scharr, Sepand Rastegar, Tanja Beil, Uwe Strähle, Rudolf Merkel, Bernd Hoffmann
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1210 (2023)
The efficient and biocompatible transfer of nucleic acids into mammalian cells for research applications or medical purposes is a long-standing, challenging task. Viral transduction is the most efficient transfer system, but often entails high safety
Externí odkaz:
https://doaj.org/article/09b2dbc7f9744aafa81e8f90d6398fd5
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background The electromechanical function of myocardial tissue depends on the intercellular communication between cardiomyocytes (CMs) as well as their crosstalk with other cell types. Cell injury, and subsequent death trigger inflammation a
Externí odkaz:
https://doaj.org/article/14ef8f4892ad4e3fa4b5f5f0aa3f49d1
Autor:
Jella-Andrea Abraham, Stefan Blaschke, Samar Tarazi, Georg Dreissen, Sabine U. Vay, Michael Schroeter, Gereon R. Fink, Rudolf Merkel, Maria A. Rueger, Bernd Hoffmann
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The neural stem cell (NSC) niche is a highly vascularized microenvironment that supplies stem cells with relevant biological and chemical cues. However, the NSCs’ proximity to the vasculature also means that the NSCs are subjected to permanent tiss
Externí odkaz:
https://doaj.org/article/b792b2c9e00f49278922e665639787db
Autor:
Josip Augustin Janeš, Cornelia Monzel, Daniel Schmidt, Rudolf Merkel, Udo Seifert, Kheya Sengupta, Ana-Sunčana Smith
Publikováno v:
Physical Review X, Vol 12, Iss 3, p 031030 (2022)
Fluctuations of surfaces that harbor reactive molecules interacting across the intervening space strongly influence the reaction kinetics. One such paradigmatic system is the cell membrane, with associated proteins, binding to an interior or an exter
Externí odkaz:
https://doaj.org/article/8e8a8a9ad9a84cd382fe5edbba26feed