Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rudolf K. Beran"'
Autor:
Christine M. Livingston, Dhivya Ramakrishnan, Michel Strubin, Simon P. Fletcher, Rudolf K. Beran
Publikováno v:
Viruses, Vol 9, Iss 4, p 69 (2017)
Hepatitis B X protein (HBx) plays an essential role in the hepatitis B virus (HBV) replication cycle, but the function of HBx has been elusive until recently. It was recently shown that transcription from the HBV genome (covalently-closed circular DN
Externí odkaz:
https://doaj.org/article/ebe438cd3f0b4e798ddc6665a854dacc
Autor:
Fabien Abdul, Aurélie Diman, Bastien Baechler, Dhivya Ramakrishnan, Dmytro Kornyeyev, Rudolf K. Beran, Simon P. Fletcher, Michel Strubin
Publikováno v:
Nature Structural & Molecular Biology. 29:922-931
In addition to its role in chromosome maintenance, the six-membered Smc5/6 complex functions as a restriction factor that binds to and transcriptionally silences viral and other episomal DNA. However, the underlying mechanism is unknown. Here, we sho
Autor:
Fabien Abdul, Aurélie Diman, Bastien Baechler, Dhivya Ramakrishnan, Dmytro Kornyeyev, Rudolf K. Beran, Simon P. Fletcher, Michel Strubin
Publikováno v:
Nature Structural & Molecular Biology.
Autor:
Julie Lucifora, Dulce Alfaiate, Caroline Pons, Maud Michelet, Ricardo Ramirez, Floriane Fusil, Fouzia Amirache, Axel Rossi, Anne-Flore Legrand, Emilie Charles, Serena Vegna, Rayan Farhat, Michel Rivoire, Guillaume Passot, Nicolas Gadot, Barbara Testoni, Charlotte Bach, Thomas F. Baumert, Anastasia Hyrina, Rudolf K. Beran, Fabien Zoulim, Andre Boonstra, Hildegard Büning, Eloi R. Verrier, François-Loïc Cosset, Simon P. Fletcher, Anna Salvetti, David Durantel
Publikováno v:
Journal of Hepatology
Journal of Hepatology, In press, ⟨10.1016/j.jhep.2023.01.005⟩
Journal of Hepatology, 78(5), 958-970. Elsevier
Journal of Hepatology, In press, ⟨10.1016/j.jhep.2023.01.005⟩
Journal of Hepatology, 78(5), 958-970. Elsevier
Background & Aims: Chronic coinfection with HBV and HDV leads to the most aggressive form of chronic viral hepatitis. Herein, we aimed to elucidate the molecular mechanisms underlying the widely reported observation that HDV interferes with HBV in mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3b3eff3a87ef013cb5c6dbae104bda
Autor:
Dara Burdette, Anastasia Hyrina, Zhijuan Song, Rudolf K. Beran, Tara Cheung, Sarah Gilmore, Tetsuya Kobayashi, Li Li, Yang Liu, Anita Niedziela-Majka, Jonathan Medley, Upasana Mehra, Philip Morganelli, Nikolai Novikov, Congrong Niu, Danny Tam, Jennifer Tang, Jianhong Wang, Qin Yue, Simon P. Fletcher, Meghan M. Holdorf, William E. Delaney, Becket Feierbach, Scott Lazerwith
Publikováno v:
Antimicrobial agents and chemotherapy.
The standard of care for the treatment of chronic hepatitis B (CHB) is typically lifelong treatment with nucleos(t)ide analogs (NAs), which suppress viral replication and provide long-term clinical benefits. However, infectious virus can still be det
Autor:
Annie, Prud'homme-Généreux, Rudolf K, Beran, Isabelle, Iost, C Shane, Ramey, George A, Mackie, Robert W, Simons
Publikováno v:
Molecular microbiology. 54(5)
Escherichia coli contains at least five ATP-dependent DEAD-box RNA helicases which may play important roles in macromolecular metabolism, especially in translation and mRNA decay. Here we demonstrate that one member of this family, CsdA, whose expres
Autor:
Congrong Niu, Christine M Livingston, Li Li, Rudolf K Beran, Stephane Daffis, Dhivya Ramakrishnan, Dara Burdette, Leanne Peiser, Eduardo Salas, Hilario Ramos, Mei Yu, Guofeng Cheng, Michel Strubin, William E Delaney, Simon P Fletcher
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169648 (2017)
The structural maintenance of chromosome 5/6 complex (Smc5/6) is a restriction factor that represses hepatitis B virus (HBV) transcription. HBV counters this restriction by expressing HBV X protein (HBx), which targets Smc5/6 for degradation. However
Externí odkaz:
https://doaj.org/article/289b65f6ddb14f2da1dab20a156f9d07