Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Rudolf J Wiesner"'
Autor:
Swaraj Basu, Xie Xie, Jay P Uhler, Carola Hedberg-Oldfors, Dusanka Milenkovic, Olivier R Baris, Sammy Kimoloi, Stanka Matic, James B Stewart, Nils-Göran Larsson, Rudolf J Wiesner, Anders Oldfors, Claes M Gustafsson, Maria Falkenberg, Erik Larsson
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009242 (2020)
Deletions and duplications in mitochondrial DNA (mtDNA) cause mitochondrial disease and accumulate in conditions such as cancer and age-related disorders, but validated high-throughput methodology that can readily detect and discriminate between thes
Externí odkaz:
https://doaj.org/article/b37608b27ed04fa5a6f640ac89a4920d
Autor:
David Pla-Martin, Rudolf J Wiesner
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008140 (2019)
Externí odkaz:
https://doaj.org/article/32b245300c4f40b5969f6d28b7665eb7
Autor:
Christina Ising, Sybille Koehler, Sebastian Brähler, Carsten Merkwirth, Martin Höhne, Olivier R Baris, Henning Hagmann, Martin Kann, Francesca Fabretti, Claudia Dafinger, Wilhelm Bloch, Bernhard Schermer, Andreas Linkermann, Jens C Brüning, Christine E Kurschat, Roman‐Ulrich Müller, Rudolf J Wiesner, Thomas Langer, Thomas Benzing, Paul Thomas Brinkkoetter
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 3, Pp 275-287 (2015)
Abstract Mitochondrial dysfunction and alterations in energy metabolism have been implicated in a variety of human diseases. Mitochondrial fusion is essential for maintenance of mitochondrial function and requires the prohibitin ring complex subunit
Externí odkaz:
https://doaj.org/article/aaed36cafd0a43ab8e7e6120f044f0e0
Autor:
Oliver Coutelle, Hue‐Tran Hornig‐Do, Axel Witt, Maria Andree, Lars M Schiffmann, Michael Piekarek, Kerstin Brinkmann, Jens M Seeger, Maxim Liwschitz, Satomi Miwa, Michael Hallek, Martin Krönke, Aleksandra Trifunovic, Sabine A Eming, Rudolf J Wiesner, Ulrich T Hacker, Hamid Kashkar
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 5, Pp 624-639 (2014)
Abstract In the normal quiescent vasculature, only 0.01% of endothelial cells (ECs) are proliferating. However, this proportion increases dramatically following the angiogenic switch during tumor growth or wound healing. Recent evidence suggests that
Externí odkaz:
https://doaj.org/article/828c57f592b542438293c1257a5a9937
Autor:
Ulla Renne, Martina Langhammer, Julia Brenmoehl, Christina Walz, Anja Zeissler, Armin Tuchscherer, Marion Piechotta, Rudolf J Wiesner, Maximilian Bielohuby, Andreas Hoeflich
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79788 (2013)
AIMS/HYPOTHESIS: Visceral obesity holds a central position in the concept of the metabolic syndrome characterized by glucose intolerance in humans. However, until now it is unclear if obesity by itself is responsible for the development of glucose in
Externí odkaz:
https://doaj.org/article/d034b95bf3d44322955807fb217eeccd
Autor:
Andras Franko, Olivier R Baris, Eva Bergschneider, Christine von Toerne, Stefanie M Hauck, Michaela Aichler, Axel K Walch, Wolfgang Wurst, Rudolf J Wiesner, Ian C D Johnston, Martin Hrabĕ de Angelis
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82392 (2013)
To better understand molecular mechanisms regulating changes in metabolism, as observed e.g. in diabetes or neuronal disorders, the function of mitochondria needs to be precisely determined. The usual isolation methods such as differential centrifuga
Externí odkaz:
https://doaj.org/article/c4ffcc322db246078027a6b3eea701fe
Autor:
Sammy Kimoloi, Ayesha Sen, Stefan Guenther, Thomas Braun, Tobias Brügmann, Philipp Sasse, Rudolf J. Wiesner, David Pla‐Martín, Olivier R. Baris
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle, 2022, 13 (4), pp.2132-2145. ⟨10.1002/jcsm.13026⟩
Journal of Cachexia, Sarcopenia and Muscle, 2022, 13 (4), pp.2132-2145. ⟨10.1002/jcsm.13026⟩
International audience; BackgroundMitochondrial dysfunction caused by mitochondrial (mtDNA) deletions have been associated with skeletal muscle atrophy and myofibre loss. However, whether such defects occurring in myofibres cause sarcopenia is unclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee21820a5fd8eea8150fe6741477d76
https://doi.org/10.1002/jcsm.13026
https://doi.org/10.1002/jcsm.13026
Autor:
Ayesha Sen, Sebastian Kallabis, Felix Gaedke, Christian Jüngst, Julia Boix, Julian Nüchel, Kanjanamas Maliphol, Julia Hofmann, Astrid C. Schauss, Marcus Krüger, Rudolf J. Wiesner, David Pla-Martín
Publikováno v:
Nature Communications. 13
Understanding the mechanisms governing selective turnover of mutation-bearing mtDNA is fundamental to design therapeutic strategies against mtDNA diseases. Here, we show that specific mtDNA damage leads to an exacerbated mtDNA turnover, independent o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e7bc8673abd508a8ac26221dc0e550
https://doi.org/10.1038/s41467-022-34205-9
https://doi.org/10.1038/s41467-022-34205-9
Autor:
Marlene Aßfalg, Markus Rothermel, Thomas Paß, Konrad M. Ricke, Rudolf J. Wiesner, Sandra Blaess, Marianna Tolve
Publikováno v:
Molecular neurobiology 57(9), 3646-3657 (2020). doi:10.1007/s12035-020-01947-w
Molecular Neurobiology
Molecular Neurobiology
Molecular neurobiology 57(9), 3646-3657 (2020). doi:10.1007/s12035-020-01947-w
Published by Humana Press, Totowa, NJ
Published by Humana Press, Totowa, NJ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ec22ecd1e8d474a61c3a15db05754c
https://doi.org/10.1007/s12035-020-01947-w
https://doi.org/10.1007/s12035-020-01947-w
Autor:
Jana Knuever, Nicole Riet, Joanna L. Elson, Robert W. Taylor, Rudolf J. Wiesner, Julia Boix, Emma L. Blakely, Anton Vila Sanjurjo, Angela Bieling, Hinrich Abken, Sophie Haumann, Hamid Kashkar, Hue-Tran Hornig-Do
Publikováno v:
Carcinogenesis. 41:1735-1745
Functioning mitochondria are crucial for cancer metabolism, but aerobic glycolysis is still considered to be an important pathway for energy production in many tumor cells. Here we show that two well established, classic Hodgkin lymphoma (cHL) cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0eea2ee99d74f05185c49b554c13a4
https://doi.org/10.1093/carcin/bgaa032
https://doi.org/10.1093/carcin/bgaa032