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pro vyhledávání: '"Rudolf G. Krause"'
Autor:
Yu-Wen Li, George O. Tora, Snjezana Lelas, Kim A. Johnson, Matthew T. Taber, Joanne J. Bronson, Michael F. Parker, Rudolf G. Krause, Amy Newton, Robert L. Bertekap, Kelly D. Lengyel, Kevin W. Gillman, Nicholas J. Lodge, Rick L. Pieschl, John E. Macor, Andrew P. Degnan, Silva Mark, Sarah J. Taylor
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:407-411
A series of substituted pyridines, ether linked to a phenylpiperidine core were optimized for dual NK(1)/SERT affinity. Optimization based on NK(1)/SERT binding affinities, and minimization of off-target ion channel activity lead to the discovery of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357bdb8f1a8f0c5d53b0870959d77c3f
https://doi.org/10.1016/j.bmcl.2012.11.094
https://doi.org/10.1016/j.bmcl.2012.11.094
