Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Rudolf Götz"'
Autor:
Verena Pfeiffer, Rudolf Götz, Guadelupe Camarero, Helmut Heinsen, Robert Blum, Ulf Rüdiger Rapp
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0192067 (2018)
RAF kinases are major constituents of the mitogen activated signaling pathway, regulating cell proliferation, differentiation and cell survival of many cell types, including neurons. In mammals, the family of RAF proteins consists of three members, A
Externí odkaz:
https://doaj.org/article/282323baf53f4853973631d5241f17a7
Autor:
Rudolf Götz, Michael Sendtner
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100944 (2014)
TrkB mediates the effects of brain-derived neurotrophic factor (BDNF) in neuronal and nonnneuronal cells. Based on recent reports that TrkB can also be transactivated through epidermal growth-factor receptor (EGFR) signaling and thus regulates migrat
Externí odkaz:
https://doaj.org/article/14ed7f336e334149b102e1861106abd3
Autor:
Verena Pfeiffer, Rudolf Götz, Chaomei Xiang, Guadelupe Camarero, Attila Braun, Yina Zhang, Robert Blum, Helmut Heinsen, Bernhard Nieswandt, Ulf R Rapp
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58259 (2013)
This study focuses on the role of the kinase BRaf in postnatal brain development. Mice expressing truncated, non-functional BRaf in neural stem cell-derived brain tissue demonstrate alterations in the cerebellum, with decreased sizes and fuzzy border
Externí odkaz:
https://doaj.org/article/454c7540f6d349cd8d2ff16a7f2fce01
Autor:
Emanuele Zanucco, Rudolf Götz, Tamara Potapenko, Irene Carraretto, Semra Ceteci, Fatih Ceteci, Werner Seeger, Rajkumar Savai, Ulf R Rapp
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29093 (2011)
Growth factor induced signaling cascades are key regulatory elements in tissue development, maintenance and regeneration. Perturbations of these cascades have severe consequences, leading to developmental disorders and neoplastic diseases. As a major
Externí odkaz:
https://doaj.org/article/47f70ea4f9b04b58b8a63df0adffa01b
Autor:
Katharina Kapoor, Dorothea Wilhelm, Claudia Neumeister, Marcus Rudolf Götz, Ulrich Schwantes, Gabriele Bleckert, Lilli Gerstenmaier, Alen Jambrecina
Publikováno v:
Open Access Journal of Clinical Trials.
Katharina Kapoor,1 Dorothea Wilhelm,1 Claudia Neumeister,2 Marcus Rudolf Götz,2 Ulrich Schwantes,2 Gabriele Bleckert,3 Lilli Gerstenmaier,4 Alen Jambrecina4 1Clinical Research, Proderm GmbH, Schenefeld/Hamburg, Germany; 2Research and Development,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d011ad00b42ee01b9117944c504294
https://www.dovepress.com/treatment-of-oropharyngeal-symptoms-a-prospective-single-dose-placebo--peer-reviewed-fulltext-article-OAJCT
https://www.dovepress.com/treatment-of-oropharyngeal-symptoms-a-prospective-single-dose-placebo--peer-reviewed-fulltext-article-OAJCT
Autor:
Axel Ullrich, Ulf R. Rapp, Katharina Weidmann, Rajkumar Savai, Verena Pfeiffer, Nefertiti El-Nikhely, Emanuele Zanucco, Rudolf Götz, Werner Seeger
Publikováno v:
Journal of Biological Chemistry. 289:26804-26816
Tumors are often greatly dependent on signaling cascades promoting cell growth or survival and may become hypersensitive to inactivation of key components within these signaling pathways. Ras and RAF mutations found in human cancer confer constitutiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb776267d1382cf46d392e9ef80f13e8
https://doi.org/10.1074/jbc.m114.558999
https://doi.org/10.1074/jbc.m114.558999
Autor:
Rudolf Götz, Frank Schön
Publikováno v:
Medizintechnik ISBN: 9783662487709
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c6f6124e36f3eca14c5c7e330f9300
https://doi.org/10.1007/978-3-662-48771-6_20
https://doi.org/10.1007/978-3-662-48771-6_20
Autor:
Ulf R. Rapp, Kathrin Schmitt, Leona Probst, Fatih Ceteci, Stefan Gaubatz, Nina Reichert, Tanja Ulrich, Sebastian Wurster, Stefanie Hauser, Roland Moll, Rudolf Götz
Publikováno v:
Molecular and Cellular Biology. 30:2896-2908
The retinoblastoma tumor suppressor protein (pRB) and related p107 and p130 "pocket proteins" function together with the E2F transcription factors to repress gene expression during the cell cycle and development. Recent biochemical studies have ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b7655ddef1f3a83d5f441c8ebc2631
https://doi.org/10.1128/mcb.00028-10
https://doi.org/10.1128/mcb.00028-10
Autor:
Esther Asan, Semra Ceteci, Christiaan Karreman, Fatih Ceteci, Boris W Kramer, Rudolf Götz, Ulf R. Rapp
Publikováno v:
Cancer Cell. 12:145-159
SummaryProgression of non-small-cell lung cancer (NSCLC) to metastasis is poorly understood. Two genetic approaches were used to evaluate the role of adherens junctions in a C-RAF driven mouse model for NSCLC: conditional ablation of the cdh1 gene an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2640c70a99e9b99581f8728e41e3fe8
https://doi.org/10.1016/j.ccr.2007.06.014
https://doi.org/10.1016/j.ccr.2007.06.014
Autor:
Frank Schön, Rudolf Götz
Publikováno v:
Medizintechnik ISBN: 9783662455388
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3ba68e2ee9306251dd58c6c215a38f8
https://doi.org/10.1007/978-3-662-45538-8_20-1
https://doi.org/10.1007/978-3-662-45538-8_20-1