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Akademický článek

Non-human primate model of long-COVID identifies immune associates of hyperglycemia

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Abstract Hyperglycemia, and exacerbation of pre-existing deficits in glucose metabolism, are manifestations of the post-acute sequelae of SARS-CoV-2. Our understanding of metabolic decline after acute COVID-19 remains unclear due to the lack of anima

Externí odkaz: https://doaj.org/article/f08910814723411b8c7b83f16cf5d078

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Akademický článek

Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

COVID-19 can result in neurological manifestations and animal models could provide insights into the mechanisms. Here, the authors describe neuroinflammation, microhemorrhages and brain hypoxia in SARS-CoV-2 infected non-human primates, including in

Externí odkaz: https://doaj.org/article/0c1be27d8686492ebe212a4588149d65

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Akademický článek

SARS-CoV-2 infection of the pancreas promotes thrombofibrosis and is associated with new-onset diabetes

Autor: Mirza Muhammad Fahd Qadir, Manika Bhondeley, Wandy Beatty, Dina D. Gaupp, Lara A. Doyle-Meyers, Tracy Fischer, Ishitri Bandyopadhyay, Robert V. Blair, Rudolf Bohm, Jay Rappaport, Eric Lazartigues, Richard S. Vander Heide, Jay K. Kolls, Xuebin Qin, Franck Mauvais-Jarvis

Publikováno v: JCI Insight, Vol 6, Iss 16 (2021)

Evidence suggests an association between severe acute respiratory syndrome–cornavirus-2 (SARS-CoV-2) infection and the occurrence of new-onset diabetes. We examined pancreatic expression of angiotensin-converting enzyme 2 (ACE2) and transmembrane s

Externí odkaz: https://doaj.org/article/ab20e4679d6241fc94e5adaa63e03b0e

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Akademický článek

Allometry and Ecology of the Bilaterian Gut Microbiome

Publikováno v: mBio, Vol 9, Iss 2 (2018)

ABSTRACT Classical ecology provides principles for construction and function of biological communities, but to what extent these apply to the animal-associated microbiota is just beginning to be assessed. Here, we investigated the influence of severa

Externí odkaz: https://doaj.org/article/8ce2e460419144ca8074efe69634a3ee

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Akademický článek

Evaluation of a therapy for Idiopathic Chronic Enterocolitis in rhesus macaques (Macaca mulatta) and linked microbial community correlates

Autor: Joshua M. Taylor, Erik L. Clarke, Kate Baker, Abigail Lauder, Dorothy Kim, Aubrey Bailey, Gary D. Wu, Ronald G. Collman, Lara Doyle-Meyers, Kasi Russell-Lodrigue, James Blanchard, Frederic D. Bushman, Rudolf Bohm

Publikováno v: PeerJ, Vol 6, p e4612 (2018)

Idiopathic chronic enterocolitis (ICE) is one of the most commonly encountered and difficult to manage diseases of captive rhesus macaques (Macaca mulatta). The etiology is not well understood, but perturbations in gut microbial communities have been

Externí odkaz: https://doaj.org/article/7cfe6e3d6b9f4c3e84c2de0fb8b778ac

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Akademický článek

Myocarditis, disseminated infection, and early viral persistence following experimental coxsackievirus B infection of cynomolgus monkeys.

Autor: Cheryl E Cammock, Nancy J Halnon, Jill Skoczylas, James Blanchard, Rudolf Bohm, Christopher J Miller, Chi Lai, Paul A Krogstad

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e74569 (2013)

Coxsackievirus B (CVB) infection is a common cause of acute viral myocarditis. The clinical presentation of myocarditis caused by this enterovirus is highly variable, ranging from mildly symptoms to complete hemodynamic collapse. These variations in

Externí odkaz: https://doaj.org/article/9a44a3a7588c46ecabba8185c4e07f5b

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SARS‐CoV‐2‐associated neuropathology in non‐human primates

Publikováno v: The FASEB Journal

SARS‐CoV‐2 infection impacts multiple organ systems, including the central nervous system (CNS). Multiple reports have described a variety of neurological manifestations associated with infection that may contribute to worsening COVID‐19. The n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6486ed5fe69d7791a4a12a255f1f81
http://europepmc.org/articles/PMC8239881

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Evaluation of a therapy for Idiopathic Chronic Enterocolitis in rhesus macaques (

Autor: Joshua M, Taylor, Erik L, Clarke, Kate, Baker, Abigail, Lauder, Dorothy, Kim, Aubrey, Bailey, Gary D, Wu, Ronald G, Collman, Lara, Doyle-Meyers, Kasi, Russell-Lodrigue, James, Blanchard, Frederic D, Bushman, Rudolf, Bohm

Publikováno v: PeerJ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71516a8cbe2c01102f388e8496218f90
https://pubmed.ncbi.nlm.nih.gov/29666764

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