Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Rudolf, Matusch"'
Autor:
Daniela Roell, Sophie Bartsch, Tsion E Abraham, Martin E. van Royen, Rudolf Matusch, Wiebke Hessenkemper, Florian Kraft, Aria Baniahmad, Adriaan B. Houtsmuller, Monique Hauschild, Thomas W. Rösler
Publikováno v:
Journal of Steroid Biochemistry and Molecular Biology, 188, 59-70. Elsevier Ltd.
Androgen receptor (AR) antagonists are used for hormone therapy of prostate cancer (PCa). However resistance to the treatment occurs eventually. One possible reason is the occurrence of AR mutations that prevent inhibition of AR-mediated transactivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4909148b01de07369373540b26b7716
https://pure.eur.nl/en/publications/b533bb5a-9c2e-45c8-888c-549ecd9d7f2e
https://pure.eur.nl/en/publications/b533bb5a-9c2e-45c8-888c-549ecd9d7f2e
Publikováno v:
Chemical Biology & Drug Design. 77:450-459
A plant extract from the fruits of saw palmetto, which is currently used to treat the androgen-dependent benign prostatic hyperplasia and PCa, served as source for new structure variants. We investigated the antiandrogenic potential of an ethanolic t
Autor:
Sascha Illgner, Rudolf Matusch
Publikováno v:
Archiv der Pharmazie. 338:49-52
The biotransformation of the anticholinergic quinazoline alkaloid Desoxypeganine is studied by means of aerobic incubation with the non-induced supernatant obtained at 9000g from rabbit liver homogenates as enzyme source followed by an admixture of N
Publikováno v:
Planta Medica. 75:184-186
The chemical composition of the hydrodistillate won by steam distillation from the fruits of Serenoa repens (W. Bartram), a well known phytomedicine against benign prostatic hyperplasia (BPH), was analyzed by GC-MS. It resulted in the identification
Autor:
Suttiporn Chaichana, Thawatchai Santisuk, Andrea Sinz, Floris van Elsäcker, Rudolf Matusch, Vichai Reutrakul
Publikováno v:
Phytochemistry. 50:1069-1072
p -Coumaroyl- β -phenethylamine (1) and 2′,3′-dihydroxy-4′,6′-dimethoxydihydrochalcone (2) were isolated by preparative HPLC from a methanolic extract of Anomianthus dulcis leaves. This is the first time that these compounds were isolated fr
Autor:
Vichai Reutrakul, Thawatchai Santisuk, Thomas Kämpchen, Rudolf Matusch, Andrea Sinz, Sirichai Wangcharoentrakul, Winfried Fiedler, Jurgen G. Schmidt, Suttiporn Chaichana
Publikováno v:
Helvetica Chimica Acta. 81:1608-1615
The hexane extract from the leaves of Dasymaschalon sootepenseCraib (Annonaceae) showed strong cytotoxic activity against the L1210 tumor cell line. Activity-directed fractionation of the extract by column chromatography on silica gel and high-pressu
Publikováno v:
Phytochemistry. 47:1393-1396
Two novel flavonol glycosides have been isolated from a methanolic extract of Dasymaschalon sootepense leaves. They are the 3′-neohesperidoside and 3′(6G-α-rhamnosylneohesperidoside) of quercetin 3,7-dimethyl ether.
Publikováno v:
Phytochemistry. 40:1303-1306
Three new alkaloids, 10-norpluviine, 1-O-acetyl-10-norpluviine and 1,10-diacetyl-10-norpluviine, have been found in bulbs of Narcissus pseudonarcissus. The known O-acetylgalanthamine is reported for the first time as a natural product. 1,10-Diacetyl-
Publikováno v:
Phytochemistry. 38:773-776
An alkaloid extract of Narcissus/pseudonarcissus was examined by means of gas chromatography-mass spectrometry (GC-EIMS and GC-CIMS). GC-MS of underivatized Amaryllidaceae alkaloids was performed for the first time. Most of the alkaloids seem to be s
Publikováno v:
Helvetica Chimica Acta. 77:1611-1615
Formation, X-Ray Crystal Structure, and Absolute Configuration of (−)-N-(Chloromethyl)galanthaminium Chloride The acetylcholinesterase inhibitor galanthamine (1), main alkaloid of several Narcissus species, readily forms a quaternary ammonium salt