Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rudimar L Frozza"'
Autor:
Julia R Clarke, Natalia M Lyra e Silva, Claudia P Figueiredo, Rudimar L Frozza, Jose H Ledo, Danielle Beckman, Carlos K Katashima, Daniela Razolli, Bruno M Carvalho, Renata Frazão, Marina A Silveira, Felipe C Ribeiro, Theresa R Bomfim, Fernanda S Neves, William L Klein, Rodrigo Medeiros, Frank M LaFerla, Jose B Carvalheira, Mario J Saad, Douglas P Munoz, Licio A Velloso, Sergio T Ferreira, Fernanda G De Felice
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 2, Pp 190-210 (2015)
Abstract Alzheimer's disease (AD) is associated with peripheral metabolic disorders. Clinical/epidemiological data indicate increased risk of diabetes in AD patients. Here, we show that intracerebroventricular infusion of AD‐associated Aβ oligomer
Externí odkaz:
https://doaj.org/article/bfe3876cdb4d49808c5c97e93ba78817
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Alzheimer's disease (AD), the most common form of dementia in late life, will become even more prevalent by midcentury, constituting a major global health concern with huge implications for individuals and society. Despite scientific breakthroughs du
Externí odkaz:
https://doaj.org/article/aaa7e9b3faf54ab8a5a0231d164a9540
Autor:
Lauren L. Zamin, Patrícia Dillenburg-Pilla, Ricardo Argenta-Comiran, Ana Paula Horn, Fabrício Simão, Melissa Nassif, Daniéli Gerhardt, Rudimar L. Frozza, Christianne Salbego
Publikováno v:
Neurobiology of Disease, Vol 24, Iss 1, Pp 170-182 (2006)
Here we investigated the neuroprotective effect of resveratrol in an in vitro model of ischemia. We used organotypic hippocampal cultures exposed to oxygen–glucose deprivation (OGD). In OGD-vehicle exposed cultures, about 46% of the hippocampus was
Externí odkaz:
https://doaj.org/article/3af4cf938f27490ca189eac791117f98
Autor:
Rudimar L, Frozza, Andressa, Bernardi, Juliana B, Hoppe, André B, Meneghetti, Ana M O, Battastini, Adriana R, Pohlmann, Sílvia S, Guterres, Christianne, Salbego
Publikováno v:
Journal of biomedical nanotechnology. 9(12)
Resveratrol, a natural polyphenolic compound, has attracted considerable interest for its anti-inflammatory and neuroprotective properties. However, the biological effects of resveratrol appear strongly limited because it is photosensitive, easily ox
Autor:
Fabrício, Figueiró, Andressa, Bernardi, Rudimar L, Frozza, Thatiana, Terroso, Alfeu, Zanotto-Filho, Elisa H F, Jandrey, José Claudio F, Moreira, Christianne G, Salbego, Maria I, Edelweiss, Adriana R, Pohlmann, Sílvia S, Guterres, Ana Maria O, Battastini
Publikováno v:
Journal of biomedical nanotechnology. 9(3)
The development of novel therapeutic strategies to treat gliomas remains critical as a result of the poor prognoses, inef-. ficient therapies and recurrence associated with these tumors. In this context, biodegradable nanoparticles are emerging as ef
Autor:
Rudimar L, Frozza, Andressa, Bernardi, Karina, Paese, Juliana B, Hoppe, Thaline, da Silva, Ana M O, Battastini, Adriana R, Pohlmann, Silvia S, Guterres, Christianne, Salbego
Publikováno v:
Journal of biomedical nanotechnology. 6(6)
Several studies have reported that orally ingested trans-resveratrol is extensively metabolized in the enterocyte before it enters the blood and target organs. Additionally, trans-resveratrol is photosensitive, easily oxidized and presents unfavorabl