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pro vyhledávání: '"Rudiger Kaspera"'
Autor:
Rudiger Kaspera, Gernot K Klein, Begona Barroso-Fernandez, Virginie Kerbusch, Dorien Groenendaal-van de Meent, Martin den Adel, Piergiorgio Galletti
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Background and Objectives Roxadustat is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor for anemia in chronic kidney disease. The pharmacokinetics, metabolic profile, and pharmacodynamics of roxadustat were investigated in subj
Autor:
Rudiger Kaspera, Martin den Adel, Gernot K Klein, Virginie Kerbusch, Begona Barroso-Fernandez, Piergiorgio Galletti, Dorien Groenendaal-van de Meent
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims Roxadustat is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor used at titrated doses to treat anaemia in CKD patients. This study investigated the pharmacokinetics (PK), metabolic profile, pharmacodynamics,
Publikováno v:
Food Biotechnology. 15:99-111
Previous research in our lab investigated the stimulatory effects of phenolic elicitors on plant seed development and the production of phenolics for lignification and nutraceutically relevant antioxidants. Metabolic flux of metabolites through the p