Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Rudiger, Woscholski"'
Autor:
D. Christopher Braddock, Anna Duran-Corbera, Masih Nilforoushan, Ziye Yang, Tianyou He, Gajan Santhakumar, Karim A. Bahou, Henry S. Rzepa, Rudiger Woscholski, Andrew J. P. White
Publikováno v:
Journal of Natural Products. 85:2650-2655
We report an improved total synthesis of 4,5-dibromo-9,10-dihydrophenanthrene-2,3,6,7-tetraol, (±)-polysiphenol, via intermolecular McMurray dimerization of 5-bromovanillin and subsequent intramolecular oxidative coupling as the key steps. The synth
Autor:
Rudiger Woscholski, Markus Kostrzewa, Gerald Larrouy-Maumus, Philippa England, Andy Corran, Wenhao Tang, Kofo Saromi
Publikováno v:
Rapid Communications in Mass Spectrometry. 34
Rationale Glycosyl-inositol-phospho-ceramides (GIPCs) or glycosylphosphatidylinositol-anchored fungal polysaccharides are known to be major lipids in plant and fungal plasma membranes and to play an important role in stress adaption. However, their a
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Phosphatidylinositol phosphates (PIPs) are membrane phospholipids that play crucial roles in a wide range of cellular processes. Their function is dictated by the number and positions of the phosphate groups in the inositol ring (with seven different
Autor:
Rudiger Woscholski, Kerry O’Donnelly, Jonathan G. D. Rains, Nicholas J. Long, Tom H. Oliver, Laura M. C. Barter
Publikováno v:
ACS Catalysis. 9:1353-1365
Carbonic anhydrase (CA) mimics are often studied with a focus on the hydration of CO2 for atmospheric carbon capture. Consequently, the reverse reaction (dehydration of HCO3–) has received minimal attention, so much so that the rate-limiting step o
Autor:
Marie-Charlotte Domart, Tina M C Hobday, Christopher J Peddie, Gary H C Chung, Alan Wang, Karen Yeh, Nirmal Jethwa, Qifeng Zhang, Michael J O Wakelam, Rudiger Woscholski, Richard D Byrne, Lucy M Collinson, Dominic L Poccia, Banafshé Larijani
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51150 (2012)
The functions and morphology of cellular membranes are intimately related and depend not only on their protein content but also on the repertoire of lipids that comprise them. In the absence of in vivo data on lipid asymmetry in endomembranes, it has
Externí odkaz:
https://doaj.org/article/740a89a7ae874dad8993050362785356
Autor:
Marie Garnier-Lhomme, Richard D Byrne, Tina M C Hobday, Stephen Gschmeissner, Rudiger Woscholski, Dominic L Poccia, Erick J Dufourc, Banafshé Larijani
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4255 (2009)
The cytoplasm of eukaryotic cells is a highly dynamic compartment where membranes readily undergo fission and fusion to reorganize the cytoplasmic architecture, and to import, export and transport various cargos within the cell. The double membrane o
Externí odkaz:
https://doaj.org/article/2c9a01f3c39a403f8f5a09b3c91a4cbe
Publikováno v:
Synlett. 26:985-990
Phosphorylation of alcohols by phosphoryl chlorides catalysed by pyridine-N-oxide is reported. The utility of this method is demonstrated through phosphorylation of primary, secondary and a tertiary alcohol as well as phenols under mild reaction cond
Autor:
Mattia Terenghi, Rudiger Woscholski, Ramon Vilar, Marina Fedorova, David R. Klug, Agostino Cilibrizzi
Publikováno v:
Cilibrizzi, A, Terenghi, M, Fedorova, M, Woscholski, R, Klug, D & Vilar, R 2017, ' Small-molecule optical probes for cell imaging of protein sulfenylation and their application to monitor cisplatin induced protein oxidation ', Sensors And Actuators B-Chemical, vol. 258, pp. 437 . https://doi.org/10.1016/j.snb.2017.03.171
Reactive oxygen species (ROS) are considered versatile second messengers mediating fundamental biological functions. A molecular pathway by which ROS determine functional diversity is the selective oxidation of cysteine residues to form sulfenic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22513071641db73e6e47c532f4ebd9c
https://kclpure.kcl.ac.uk/en/publications/5e2d935e-9aa4-4f08-b5ba-6101fc62f9b9
https://kclpure.kcl.ac.uk/en/publications/5e2d935e-9aa4-4f08-b5ba-6101fc62f9b9
Autor:
Rudiger Woscholski, Ramon Vilar, Robin J. Leatherbarrow, Marina Fedorova, Juliet Collins, Agostino Cilibrizzi
Publikováno v:
Cilibrizzi, A, Fedorova, M, Collins, J, Leatherbarrow, R J, Woscholski, R & Vilar, R 2017, ' A tri-functional vanadium(IV) complex to detect cysteine oxidation ', DALTON TRANSACTIONS (2003), vol. 46, pp. 6994-7004 . https://doi.org/10.1039/C7DT00076F
The development of effective molecular probes to detect and image the levels of oxidative stress in cells remains a challenge. Herein we report the design, synthesis and preliminary biological evaluation of a novel optical probe to monitor oxidation
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 19:867-874