Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rudi Wilfried Jan Pauwels"'
Autor:
Dominique Louis Nestor Ghislain Surleraux, Anik Peeters, Sandra De Meyer, Rudi Wilfried Jan Pauwels, Moses Prabu-Jeyabalan, Piet Wigerinck, Celia A. Schiffer, Geert M. E. Pille, Hilde Azijn, Louis J. R. Maes, Herman Augustinus De Kock, Sandrine Marie Helene Vendeville, Wim Gaston Verschueren, Marie-Pierre de Béthune, Nancy M. King
Publikováno v:
Journal of medicinal chemistry
On the basis of structural data gathered during our ongoing HIV-1 protease inhibitors program, from which our clinical candidate TMC114 9 was selected, we have discovered new series of fused heteroaromatic sulfonamides. The further extension into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd8542a3b133ceedb9a93cedbed6ccb
https://doi.org/10.1021/jm049454n
https://doi.org/10.1021/jm049454n
Autor:
J.G Huisman, E. De Clercq, Rudi Wilfried Jan Pauwels, M P deBéthune, M. E. Kuipers, Dirk K. F. Meijer, C Smit, Piet Swart
Publikováno v:
Aids Research and Human Retroviruses, 12(9), 769-775
A number of native and modified milk proteins from bovine or human sources were analyzed for their inhibitory effects on human immunodeficiency virus type 1 (HIV-1) and HIV-2 in vitro in an MT4 cell test system, The proteins investigated were lactofe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04a3ced6321d4c4553c948f99d79c5d
https://doi.org/10.1089/aid.1996.12.769
https://doi.org/10.1089/aid.1996.12.769
Autor:
E. De Clercq, C Poujade, N Dereu, Y. Henin, T Huet, Francoise Soler, Michel Dr Evers, Jean-François Mayaux, Anne Bousseau, Rudi Wilfried Jan Pauwels
Publikováno v:
Proceedings of the National Academy of Sciences. 91:3564-3568
A series of triterpene compounds characterized by a stringent structure-activity relationship were identified as potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) replication. Currently studied botulinic derivatives have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87de6126d9515ce475a5937af89982c2
https://doi.org/10.1073/pnas.91.9.3564
https://doi.org/10.1073/pnas.91.9.3564
Autor:
Dominique Schols, T. Barzu, Rudi Wilfried Jan Pauwels, Myriam Witvrouw, Jean-Claude Lormeau, E. De Clercq, Masanori Baba, Jean Choay, Maurice Petitou, M. Level
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::086805bfbbf65f2d713bf50c23880dcc
https://doi.org/10.1002/chin.199413239
https://doi.org/10.1002/chin.199413239
Autor:
Jozef Anné, E. De Clercq, Jan Desmyter, Rudi Wilfried Jan Pauwels, Zeger Debyser, K De Vreese, N Yamamoto
Publikováno v:
Journal of General Virology. 73:1799-1804
Recently, several classes of compounds have been shown to be extremely selective inhibitors of human immunodeficiency virus type 1 (HIV-1) replication in vitro. These include the tetrahydro-imidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023a3df8758e9792146c20eeffa02125
https://doi.org/10.1099/0022-1317-73-7-1799
https://doi.org/10.1099/0022-1317-73-7-1799
Autor:
Graciela Andrei, Dominique Schols, Miklós Nagy, Rudi Wilfried Jan Pauwels, Masanori Baba, István Horváth, Jan Balzarini, Judit Györgyi-Edelényi, Raymund Machovich, Robert Snoeck, Myriam Witvrouw, E. De Clercq, Miklos Low, Johan Neyts, Mitsuaki Hosoya, Sándor Görög
Publikováno v:
Antiviral Chemistry and Chemotherapy. 1:233-240
The sulphated polymers, such as polyvinylalcohol sulphate (PVAS) and its co-polymer with acrylic acid (PAVAS), have proved to be potent inhibitors for herpes simplex virus, human cytomegalovirus, vesicular stomatitis virus, respiratory syncytial viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0608ebe7d7138e4bb11a8c38dd595ab4
https://doi.org/10.1177/095632029000100402
https://doi.org/10.1177/095632029000100402
Publikováno v:
ChemInform. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f377f242aea567ae99688e8a7d35c007
https://doi.org/10.1002/chin.199002326
https://doi.org/10.1002/chin.199002326
Autor:
Koenraad Jozef Lodewijk Marcel Andries, E. De Clercq, P. A. J. Janssen, Rudi Wilfried Jan Pauwels, Michael J. Kukla, Dominique Schols, Masanori Baba, Jan Desmyter, Zeger Debyser
Publikováno v:
Antiviral Research. 15:85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c71d04e36d624297ba8520effe0d187d
https://doi.org/10.1016/0166-3542(91)90164-m
https://doi.org/10.1016/0166-3542(91)90164-m
Autor:
Rw Jansen, E. De Clercq, Grietje Molema, Rudi Wilfried Jan Pauwels, Dominique Schols, Dkf Meijer
Publikováno v:
Antiviral Research. 15:81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac4bb95b6e54ed35da4ca5f8fd13ce79
https://doi.org/10.1016/0166-3542(91)90157-m
https://doi.org/10.1016/0166-3542(91)90157-m
Publikováno v:
Journal of Medicinal Chemistry. 32:1743-1749
A series of 2'- and 3'-fluorinated 2',3'-dideoxynucleosides and 3'-azido-2',3'-dideoxynucleosides were synthesized and evaluated for their inhibitory activity against human immunodeficiency virus-1 (HIV-1) replication in MT-4 cells. Neither conversio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d639224fc374a1ef30540ebec3770158
https://doi.org/10.1021/jm00128a013
https://doi.org/10.1021/jm00128a013