Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Rudi Glockshuber"'
The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili
Autor:
Dawid S. Zyla, Thomas Wiegand, Paul Bachmann, Rafal Zdanowicz, Christoph Giese, Beat H. Meier, Gabriel Waksman, Manuela K. Hospenthal, Rudi Glockshuber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Type 1 pili are important virulence factors of uropathogenic Escherichia coli that mediate bacterial attachment to epithelial cells in the urinary tract. The pilus rod is comprised of thousands of copies of the main structural subunit FimA a
Externí odkaz:
https://doaj.org/article/884d08eb71b24e7aa30ce532b269e3b7
Autor:
Christoph Giese, Chasper Puorger, Oleksandr Ignatov, Zuzana Bečárová, Marco E. Weber, Martin A. Schärer, Guido Capitani, Rudi Glockshuber
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Adhesive type 1 pili from uropathogenic Escherichia coli strains are filamentous, supramolecular protein complexes consisting of a short tip fibrillum and a long, helical rod formed by up to several thousand copies of the major pilus subunit
Externí odkaz:
https://doaj.org/article/d39c9c2a626e485287cd4ec9a1f3df84
Autor:
Simone Mattei, Arvid Ban, Armin Picenoni, Marc Leibundgut, Rudi Glockshuber, Daniel Boehringer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Female honeybee larvae develop into queens when they are fed exclusively with royal jelly (RJ) and major royal jelly protein 1 (MRJP1) is the main protein component of RJ. Here, the authors present the 3.5 Å cryo-EM structure of native RJ filament,
Externí odkaz:
https://doaj.org/article/ab6e39a156d443d586b7fd90a3e1ecc8
Autor:
Jessica J Stanisich, Dawid S Zyla, Pavel Afanasyev, Jingwei Xu, Anne Kipp, Eric Olinger, Olivier Devuyst, Martin Pilhofer, Daniel Boehringer, Rudi Glockshuber
Publikováno v:
eLife, Vol 9 (2020)
The glycoprotein uromodulin (UMOD) is the most abundant protein in human urine and forms filamentous homopolymers that encapsulate and aggregate uropathogens, promoting pathogen clearance by urine excretion. Despite its critical role in the innate im
Externí odkaz:
https://doaj.org/article/6e2010ca76a24c7c9142814a5644bbca
Autor:
Maximilian M. Sauer, Roman P. Jakob, Jonathan Eras, Sefer Baday, Deniz Eriş, Giulio Navarra, Simon Bernèche, Beat Ernst, Timm Maier, Rudi Glockshuber
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Catch bonds have a role in bacterial adhesion and infection by uropathogenic E. coli.Here, the authors report crystal structures, molecular dynamics simulations, ligand binding analysis and cell tracking to characterise the catch bond interaction bet
Externí odkaz:
https://doaj.org/article/15996d3b67454979a441ce96b98b7d26
Autor:
Stephan Benke, Daniel Roderer, Bengt Wunderlich, Daniel Nettels, Rudi Glockshuber, Benjamin Schuler
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-2 (2016)
Nature Communications 6: Article number: 6198 (2015); Published: 5 February 2015; Updated: 1 February 2016 In Figure 2b of this article, the sets of arrows connecting 'I' and 'M' in the kinetic scheme are inverted. The correct version of Fig. 2 appea
Externí odkaz:
https://doaj.org/article/609bed21ed2844e3a1f49ef21a4d8cc6
Autor:
Theodoros Goulas, Anna Cuppari, Raquel Garcia-Castellanos, Scott Snipas, Rudi Glockshuber, Joan L Arolas, F Xavier Gomis-Rüth
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112643 (2014)
A major bottleneck in structural, biochemical and biophysical studies of proteins is the need for large amounts of pure homogenous material, which is generally obtained by recombinant overexpression. Here we introduce a vector collection, the pCri Sy
Externí odkaz:
https://doaj.org/article/f2488450042447068930619d6eaab567
Autor:
Rudi Glockshuber
Publikováno v:
CHIMIA, Vol 55, Iss 4 (2001)
One of the central dogmas in biochemistry is the view that the biologically active, three-dimensional structure of a protein is unique and exclusively determined by its amino acid sequence, and that the active conformation of a protein represents its
Externí odkaz:
https://doaj.org/article/6ca67b99a8fd43e4ae7e3b1504468b22
Autor:
Sirine Nouri, Julien Boudet, Hiang Dreher-Teo, Frédéric H.-T. Allain, Rudi Glockshuber, Loïc Salmon, Christoph Giese
Publikováno v:
Angewandte Chemie. International Edition
In NMR spectroscopy, residual dipolar couplings (RDCs) have emerged as one of the most exquisite probes of biological structure and dynamics. The measurement of RDCs relies on the partial alignment of the molecule of interest, for example by using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdeffd38df3ea733f7a417c39ca507a7
https://doi.org/10.1002/anie.202305120
https://doi.org/10.1002/anie.202305120
Publikováno v:
Biophys J
The conserved fold of thioredoxin (Trx)-like thiol/disulfide oxidoreductases contains an invariant cis-proline residue (P76 in Escherichia coli Trx) that is essential for Trx function and that is responsible for the folding rate-limiting step. E. col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2e0d756a1a8336e35711758edaef7b
https://doi.org/10.1016/j.bpj.2021.10.040
https://doi.org/10.1016/j.bpj.2021.10.040