Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Rudi, D’Hooge"'
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S620-S621 (2023)
Externí odkaz:
https://doaj.org/article/a0b6b33eb90a4c3387087385ccf61cce
Autor:
Jens Devoght, Joris Comhair, Giovanni Morelli, Jean-Michel Rigo, Rudi D'Hooge, Chadi Touma, Rupert Palme, Ilse Dewachter, Martin vandeVen, Robert J. Harvey, Serge N. Schiffmann, Elisabeth Piccart, Bert Brône
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107400- (2023)
Summary: The glycine receptor alpha 2 (GlyRα2) is a ligand-gated ion channel which upon activation induces a chloride conductance. Here, we investigated the role of GlyRα2 in dopamine-stimulated striatal cell activity and behavior. We show that dep
Externí odkaz:
https://doaj.org/article/8acd3b1f9a4b4e29a6d2ed5ec939ddea
Autor:
Dongchen An, Guilherme Salgado Carrazoni, Ben-Hur Souto das Neves, Rudi D’Hooge, Steve Peigneur, Jan Tytgat
Publikováno v:
Biomedicines, Vol 12, Iss 2, p 454 (2024)
Cannabinoid receptors (CB1 and CB2) are promising targets for a better understanding of neurological diseases. Nevertheless, only a few ligands of CB have reached clinical application so far. Venoms are considered as interesting sources of novel biol
Externí odkaz:
https://doaj.org/article/b5313ba625424979a21860b9a7e63b66
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Pig breeding is changing rapidly due to technological progress and socio-ecological factors. New precision livestock farming technologies such as computer vision systems are crucial for automated phenotyping on a large scale for novel traits
Externí odkaz:
https://doaj.org/article/34813440b6ef4205a4f48bf8e5c46faf
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
Vital early-life dyadic interaction in mice requires a pup to signal its needs adequately, and a dam to recognize and respond to the pup’s cues accurately and timely. Previous research might have missed important biological and/or environmental ele
Externí odkaz:
https://doaj.org/article/ecd2fb3396b94ec19df649178c1daf34
Autor:
Carmen Winters, Wim Gorssen, Victoria A. Ossorio-Salazar, Simon Nilsson, Sam Golden, Rudi D’Hooge
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract All mammalian mothers form some sort of caring bond with their infants that is crucial to the development of their offspring. The Pup Retrieval Test (PRT) is the leading procedure to assess pup-directed maternal care in laboratory rodents, u
Externí odkaz:
https://doaj.org/article/e77aa8cc26ca4802b90c6c7a33bb61e2
Autor:
Sarah C. Borrie, Ellen Plasschaert, Zsuzsanna Callaerts-Vegh, Akihiko Yoshimura, Rudi D’Hooge, Ype Elgersma, Steven A. Kushner, Eric Legius, Hilde Brems
Publikováno v:
Molecular Autism, Vol 12, Iss 1, Pp 1-19 (2021)
Abstract Background RASopathies are a group of disorders that result from mutations in genes coding for proteins involved in regulating the Ras-MAPK signaling pathway, and have an increased incidence of autism spectrum disorder (ASD). Legius syndrome
Externí odkaz:
https://doaj.org/article/c34e36dab9764853acb1f0fa4ca45263
Autor:
Lindsay Poppe, Laura Rué, Mieke Timmers, Annette Lenaerts, Annet Storm, Zsuzsanna Callaerts-Vegh, Gilles Courtand, Antina de Boer, Silke Smolders, Philip Van Damme, Ludo Van Den Bosch, Rudi D’Hooge, Bart De Strooper, Wim Robberecht, Robin Lemmens
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-13 (2019)
Abstract Background EphA4 is a receptor of the ephrin system regulating spine morphology and plasticity in the brain. These processes are pivotal in the pathophysiology of Alzheimer’s disease (AD), characterized by synapse dysfunction and loss, and
Externí odkaz:
https://doaj.org/article/0285cce7c3524e97916463b91189a49d
Autor:
Nuria Domínguez-Iturza, Adrian C. Lo, Disha Shah, Marcelo Armendáriz, Anna Vannelli, Valentina Mercaldo, Massimo Trusel, Ka Wan Li, Denise Gastaldo, Ana Rita Santos, Zsuzsanna Callaerts-Vegh, Rudi D’Hooge, Manuel Mameli, Annemie Van der Linden, August B. Smit, Tilmann Achsel, Claudia Bagni
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
In humans, copy-number variants of the CYFIP1 gene have been associated with autism spectrum disorders and schizophrenia. Here, the authors characterize Cyfip1-heterozygous mice, revealing that they display deficits in brain white matter structure an
Externí odkaz:
https://doaj.org/article/45ce8718dbe54af7bd35ef3ffe5acc3a
Autor:
Lien Beckers, Ivana Geric, Stijn Stroobants, Sander Beel, Philip Van Damme, Rudi D’Hooge, Myriam Baes
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract Background Microglia play a central role in most neurological disorders, but the impact of microgliosis on brain environment and clinical functions is not fully understood. Mice lacking multifunctional protein-2 (MFP2), a pivotal enzyme in p
Externí odkaz:
https://doaj.org/article/cc0f797511704c9d955ebba5c9fc01a8