Hypoxia-Associated Factor (HAF) Mediates Neurofibromin Ubiquitination and Degradation Leading to Ras-ERK Pathway Activation in Hypoxia.

Autor: Green YS; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah., Sargis T; Department of Physiology and Biophysics, College of Medicine, University of Illinois at Chicago, Chicago, Illinois., Reichert EC; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah., Rudasi E; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah., Fuja D; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah., Jonasch E; Department of Genitourinary Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas., Koh MY; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah. mei.koh@utah.edu.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2019 May; Vol. 17 (5), pp. 1220-1232. Date of Electronic Publication: 2019 Jan 31.

HAF prevents hepatocyte apoptosis and progression to MASH and HCC through transcriptional regulation of the NF-κB pathway.

Autor: Acuña-Pilarte K; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA., Reichert EC; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA., Green YS; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA., Halberg LM; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA., Golkowski M; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA., Maguire KM, Mimche PN; Department of Pathology, University of Utah, Salt Lake City, Utah, USA., Kamdem SD; Department of Pathology, University of Utah, Salt Lake City, Utah, USA., Hu PA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA., Wright J; Department of Biochemistry, University of Utah, Salt Lake City, Utah, USA., Ducker GS; Department of Biochemistry, University of Utah, Salt Lake City, Utah, USA., Voth WP; Department of Pathology, University of Utah, Salt Lake City, Utah, USA., O'Connell RM; Department of Pathology, University of Utah, Salt Lake City, Utah, USA., McFarland SA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA., Egal ESA; Biorepository and Molecular Pathology, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA., Chaix A; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, USA., Summers SA; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, USA., Reelitz JW; Department of Biochemistry, University of Utah, Salt Lake City, Utah, USA., Maschek JA; Department of Biochemistry, University of Utah, Salt Lake City, Utah, USA., Cox JE; Department of Biochemistry, University of Utah, Salt Lake City, Utah, USA., Evason KJ; Department of Anatomic Pathology, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA., Koh MY; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2024 Sep 10. Date of Electronic Publication: 2024 Sep 10.

Effects of Sensitized Sorafenib with a Paeoniflorin and Geniposide Mixture on Liver Cancer via the NF-κB-HIF-2α-SerpinB3 Pathway.

Autor: Li, Jun-Fei, Zheng, Xiao-Rong, Zhang, Hong-Yan, Shen, Chang-Ming, Shen, Guo-xin, Jiang, Jian-Wei

Publikováno v: Evidence-based Complementary & Alternative Medicine (eCAM); 10/15/2022, p1-11, 11p, 5 Graphs

Neurofibromin Structure, Functions and Regulation.

Autor: Bergoug, Mohammed¹ (AUTHOR) bergoug_mohammed@yahoo.fr, Doudeau, Michel¹ (AUTHOR), Godin, Fabienne¹ (AUTHOR), Mosrin, Christine¹ (AUTHOR), Vallée, Béatrice¹ (AUTHOR), Bénédetti, Hélène¹ (AUTHOR) helene.benedetti@cnrs-orleans.fr

Publikováno v: Cells (2073-4409). Nov2020, Vol. 9 Issue 11, p2365. 1p.