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Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model.

Autor: Rudan Njavro J; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany., Vukicevic M; AC Immune SA, 1015 Lausanne, Switzerland., Fiorini E; AC Immune SA, 1015 Lausanne, Switzerland., Dinkel L; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany., Müller SA; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, 80333 Munich, Germany., Berghofer A; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, 80333 Munich, Germany., Bordier C; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany., Kozlov S; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany., Halle A; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany., Buschmann K; Biomedical Center (BMC), Ludwig-Maximilians University Munich, 80539 Munich, Germany., Capell A; Biomedical Center (BMC), Ludwig-Maximilians University Munich, 80539 Munich, Germany., Giudici C; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany., Willem M; Biomedical Center (BMC), Ludwig-Maximilians University Munich, 80539 Munich, Germany., Feederle R; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.; Monoclonal Antibody Core Facility, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, 80333 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Babolin C; AC Immune SA, 1015 Lausanne, Switzerland., Montanari P; AC Immune SA, 1015 Lausanne, Switzerland., Pfeifer A; AC Immune SA, 1015 Lausanne, Switzerland., Kosco-Vilbois M; AC Immune SA, 1015 Lausanne, Switzerland., Tahirovic S; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.

Publikováno v: Cells [Cells] 2022 Dec 24; Vol. 12 (1). Date of Electronic Publication: 2022 Dec 24.