Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model.

Autor: Rudan Njavro J; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany., Vukicevic M; AC Immune SA, 1015 Lausanne, Switzerland., Fiorini E; AC Immune SA, 1015 Lausanne, Switzerland., Dinkel L; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany., Müller SA; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, 80333 Munich, Germany., Berghofer A; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, 80333 Munich, Germany., Bordier C; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany., Kozlov S; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany., Halle A; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany., Buschmann K; Biomedical Center (BMC), Ludwig-Maximilians University Munich, 80539 Munich, Germany., Capell A; Biomedical Center (BMC), Ludwig-Maximilians University Munich, 80539 Munich, Germany., Giudici C; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany., Willem M; Biomedical Center (BMC), Ludwig-Maximilians University Munich, 80539 Munich, Germany., Feederle R; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.; Monoclonal Antibody Core Facility, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, 80333 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany., Babolin C; AC Immune SA, 1015 Lausanne, Switzerland., Montanari P; AC Immune SA, 1015 Lausanne, Switzerland., Pfeifer A; AC Immune SA, 1015 Lausanne, Switzerland., Kosco-Vilbois M; AC Immune SA, 1015 Lausanne, Switzerland., Tahirovic S; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.

Publikováno v: Cells [Cells] 2022 Dec 24; Vol. 12 (1). Date of Electronic Publication: 2022 Dec 24.

Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3.

Autor: Pigoni M; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Hsia HE; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Hartmann J; UK Dementia Research Institute at UCL, University College London, London, UK., Rudan Njavro J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Shmueli MD; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Department of Immunology, The Weizmann Institute of Science, Rehovot, Israel., Müller SA; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Güner G; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Tüshaus J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Kuhn PH; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Institut für Allgemeine Pathologie und Pathologische Anatomie, Technische Universität München, Munich, Germany., Kumar R; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Department of Neurology, Ludwig Maximilian University, Munich, Germany., Gao P; Department of Neurology, Ludwig Maximilian University, Munich, Germany.; Department of Translational Brain Research, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Tran ML; Max Planck Institute of Biochemistry, Martinsried, Germany.; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA., Ramazanov B; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA., Blank B; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA., Hipgrave Ederveen AL; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Von Blume J; Max Planck Institute of Biochemistry, Martinsried, Germany.; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA., Mulle C; Interdisciplinary Institute for Neuroscience, University of Bordeaux, CNRS, UMR 5297, Bordeaux, France., Gunnersen JM; Department of Anatomy and Neuroscience, University of Melbourne, Melbourne, Vic., Australia.; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Vic., Australia., Wuhrer M; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands., Rammes G; Department of Anesthesiology and Intensive Care, Klinikum rechts der Isar, Technische Universität München, Munich, Germany., Busche MA; UK Dementia Research Institute at UCL, University College London, London, UK., Koeglsperger T; Department of Neurology, Ludwig Maximilian University, Munich, Germany.; Department of Translational Brain Research, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.; Institute for Advanced Study, Technical University of Munich, Garching, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Publikováno v: The EMBO journal [EMBO J] 2020 Aug 03; Vol. 39 (15), pp. e103457. Date of Electronic Publication: 2020 Jun 22.

Aberrant glycosylation in schizophrenia: insights into pathophysiological mechanisms and therapeutic potentials.

Autor: Yanchen Feng, Lu Sun, Xue Dang, Diyan Liu, Ziyun Liao, Jianping Yao, Yunke Zhang, Ziqi Deng, Jinyao Li, Min Zhao, Feixiang Liu

Publikováno v: Frontiers in Pharmacology; 2024, p1-13, 13p

A methodology to globally assess ectodomain shedding using soluble fractions from the mouse brain.

Autor: Lobete, Miguel, Salinas, Tamel, Izquierdo-Bermejo, Sara, Socas, Silvia, Oset-Gasque, María Jesús, Dolores Martín-de-Saavedra, M.

Publikováno v: Frontiers in Psychiatry; 2024, p1-15, 15p

α 2 δ-4 and Cachd1 Proteins Are Regulators of Presynaptic Functions.

Autor: Ablinger, Cornelia¹ (AUTHOR), Eibl, Clarissa² (AUTHOR), Geisler, Stefanie M.³ (AUTHOR), Campiglio, Marta¹ (AUTHOR), Stephens, Gary J.⁴ (AUTHOR), Missler, Markus⁵ (AUTHOR), Obermair, Gerald J.^1,2 (AUTHOR) gerald.obermair@kl.ac.at

Publikováno v: International Journal of Molecular Sciences. Sep2022, Vol. 23 Issue 17, p9885. 23p.