Patterns of gastrointestinal parasite infections in bighorn sheep, Ovis canadensis, with respect to host sex and seasonality

Autor: Samridhi Rijal, Peter Neuhaus, Jack Thorley, Nigel Caulkett, Susan Kutz, Kathreen E. Ruckstuhl

Publikováno v: International Journal for Parasitology: Parasites and Wildlife, Vol 24, Iss , Pp 100950- (2024)

Males and females in sexually dimorphic species show differences in their physiology and behaviour due to differences in energetic investment into reproduction and soma. This means that the two sexes may show different patterns of parasitism at diffe

Externí odkaz: https://doaj.org/article/d2fe24536d1c4f90b430e80cf28a3897

Understanding the dependence of mean precipitation on convective treatment and horizontal resolution in tropical aquachannel experiments

Autor: H. Jung, P. Knippertz, Y. Ruckstuhl, R. Redl, T. Janjic, C. Hoose

Publikováno v: Weather and Climate Dynamics, Vol 4, Pp 1111-1134 (2023)

The Intertropical Convergence Zone (ITCZ) is a key circulation and precipitation feature in the tropics. There has been a large spread in the representation of the ITCZ in global weather and climate models for a long time, the reasons for which remai

Externí odkaz: https://doaj.org/article/ec68b72611454155814bd98702d598a5

Graphical Elastic Net and Target Matrices: Fast Algorithms and Software for Sparse Precision Matrix Estimation

Autor: Kovács, Solt, Ruckstuhl, Tobias, Obrist, Helena, Bühlmann, Peter

We consider estimation of undirected Gaussian graphical models and inverse covariances in high-dimensional scenarios by penalizing the corresponding precision matrix. While single $L_1$ (Graphical Lasso) and $L_2$ (Graphical Ridge) penalties for the

Externí odkaz: http://arxiv.org/abs/2101.02148

Systemically administered low-affinity HER2 CAR T cells mediate antitumor efficacy without toxicity

Autor: Stanley R Riddell, Ekram A Gad, Sylvain Simon, Tamer Basel Shabaneh, Andrew R Stevens, Sylvia M Stull, Kristen R Shimp, Brandon W Seaton, Carla A Jaeger-Ruckstuhl, Amanda L Koehne, Jason P Price, James M Olson, Benjamin G Hoffstrom, David Jellyman

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 2 (2024)

Background The paucity of tumor-specific targets for chimeric antigen receptor (CAR) T-cell therapy of solid tumors necessitates careful preclinical evaluation of the therapeutic window for candidate antigens. Human epidermal growth factor receptor 2

Externí odkaz: https://doaj.org/article/eef8e83670544a3da80201117fcb7911

Protocol for an evaluation of the initiation of an integrated longitudinal outpatient care model for severe chronic non-communicable diseases (PEN-Plus) at secondary care facilities (district hospitals) in 10 lower-income countries

Autor: Archana Shrestha, Biraj Man Karmacharya, Robert Kalyesubula, Isaac Ssinabulya, Zipporah Ali, Alma J Adler, Ana Olga Mocumbi, Neil Gupta, Meghnath Dhimal, Bhagawan Koirala, Gedeon Ngoga, Symaque Dusabeyezu, Gene Kwan, Gene Bukhman, Lilian Mbau, Beatriz Manuel, Giovanni Putoto, Santigie Sesay, Emily B Wroe, Yogeshwar Kalkonde, Sergio Chicumbe, Lauren Brown, Abha Shrestha, Lucia González, Matthew M Coates, Jones K Masiye, Mary Theodory Mayige, Wubaye Walelgne Dagnaw, Chiyembekezo Kachimanga, Ana Mocumbi, Ryan McBain, Apoorva Gomber, Fabio Manenti, Roma Chilengi, Yogesh Jain, Sam Patel, Gladwell Gathecha, Julie Makani, Amy McLaughlin, Celina Trujillo, Laura Drown, Reuben Mutagaywa, Todd Ruderman, Gina Ferrari, Chantelle Boudreaux, Humberto Muquingue, Mary Mayige, Jonathan Chiwanda Banda, Andrea Atzori, Neusa Bay, Wondu Bekele, Victoria M Bhambhani, Remy Bitwayiki Nkwiro, Dawson Calixte, Katia Domingues, Darius Fenelon, Innocent Kamali, Catherine Karekezi, Alexio Mangwiro, Fastone Mathew Goma, Emmanuel Mensah, Nicole Mocumbi Salipa, Alvern Mutengerere, Marta Patiño, Devashri Salvi, Fameti Taero, Emílio Tostão, Sterman Toussaint, Abhijit Gadewar, Sunil Jadhao, Chetanya Malik, Alma Adler, Victoria Bhambhani, Susan Donnellan, Kaita Domingues, Sheila Klassen, Andrew Marx, Maia Olsen, Catherine Player, Ramon Ruiz, Ada Thapa, Leslie Wentworth, Allison Westervelt, Ariana Wolgin, Emily Yale, Michael Abiyu, Lemma Ayele, Zelalem Mengistu, Temesgen Sileshi, Natnael Alemayehu, Natnael A Abebe, Nancy Larco, Gideon Ayodo, Peter Mokaya, Jones Masiye, Evelyn Chibwe, Noel Kasomekera, Nicole M Salipa, Riaze Rafik, Lucy Ramirez, Shiva Adhikary, Krishna Aryal, Phanindra Baral, Biraj Karmachaya, Abhinav Vaidhya, Ann Akiteng, Frank Mugabe, Sarah Asio Eragu, Bernard Bukar, Namasiku Siyumbwa, Wibroad Mutale, Kudakwashe Madzeke, Alaisa Mbiriri, Nyamayaro Wencelas, Porika Nyawai, Abaden Svisva, Laura Ruckstuhl

Publikováno v: BMJ Open, Vol 14, Iss 1 (2024)

Introduction The Package of Essential Noncommunicable Disease Interventions—Plus (PEN-Plus) is a strategy decentralising care for severe non-communicable diseases (NCDs) including type 1 diabetes, rheumatic heart disease and sickle cell disease, to

Externí odkaz: https://doaj.org/article/992bdf24e8ec4d74866d7214d725d384