Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ruchir Rastogi"'
Autor:
Milind Jagota, Chengzhong Ye, Carlos Albors, Ruchir Rastogi, Antoine Koehl, Nilah Ioannidis, Yun S. Song
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Background Genetic variation in the human genome is a major determinant of individual disease risk, but the vast majority of missense variants have unknown etiological effects. Here, we present a robust learning framework for leveraging satu
Externí odkaz:
https://doaj.org/article/aa502c3625e54c5291d32d735dded179
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-11 (2022)
Abstract Stopgain substitutions are the third-largest class of monogenic human disease mutations and often examined first in patient exomes. Existing computational stopgain pathogenicity predictors, however, exhibit poor performance at the high sensi
Externí odkaz:
https://doaj.org/article/cf9b6a44e98e45eea01173c7024d261f
Autor:
Reeshu Gupta, Kajal Arora, Sourav Singha Roy, Abyson Joseph, Ruchir Rastogi, Nupur Mehrotra Arora, Prabuddha K. Kundu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Viral infectious diseases threaten human health and global stability. Several vaccine platforms, such as DNA, mRNA, recombinant viral vectors, and virus-like particle-based vaccines have been developed to counter these viral infectious diseases. Viru
Externí odkaz:
https://doaj.org/article/d12100344955421080d396f454e0f78d
Autor:
Dilip Kumar, Sourav Singha Roy, Ruchir Rastogi, Kajal Arora, Avinash Undale, Reeshu Gupta, Nupur Mehrotra Arora, Prabuddha K. Kundu
Publikováno v:
Vaccines, Vol 11, Iss 4, p 743 (2023)
Background: Serological methods to conduct epidemiological survey are often directed only against the spike protein. To overcome this limitation, we have designed PRAK-03202, a virus-like particle (VLP), by inserting three antigens (Spike, envelope a
Externí odkaz:
https://doaj.org/article/84b33d3a8bbd4fc496b8745cea88f156
Autor:
Saumyabrata Mazumder, Ruchir Rastogi, Avinash Undale, Kajal Arora, Nupur Mehrotra Arora, Biswa Pratim, Dilip Kumar, Abyson Joseph, Bhupesh Mali, Vidya Bhushan Arya, Sriganesh Kalyanaraman, Abhishek Mukherjee, Aditi Gupta, Swaroop Potdar, Sourav Singha Roy, Deepak Parashar, Jeny Paliwal, Sudhir Kumar Singh, Aelia Naqvi, Apoorva Srivastava, Manglesh Kumar Singh, Devanand Kumar, Sarthi Bansal, Satabdi Rautray, Manish Saini, Kshipra Jain, Reeshu Gupta, Prabuddha Kumar Kundu
Publikováno v:
Heliyon, Vol 7, Iss 10, Pp e08124- (2021)
The rapid development of safe and effective vaccines against severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) is a necessary response to coronavirus outbreak. Here, we developed PRAK-03202, the world's first triple antigen virus-like part
Externí odkaz:
https://doaj.org/article/0dfd59dfde2d410a8ba0a7733014be0b
Autor:
Saumyabrata Mazumder, Ruchir Rastogi, Avinash Undale, Kajal Arora, Nupur Mehrotra Arora, Biswa Pratim, Dilip Kumar, Abyson Joseph, Bhupesh Mali, Vidya Bhushan Arya, Sriganesh Kalyanaraman, Abhishek Mukherjee, Aditi Gupta, Swaroop Potdar, Sourav Singha Roy, Deepak Parashar, Jeny Paliwal, Sudhir Kumar Singh, Aelia Naqvi, Apoorva Srivastava, Manglesh Kumar Singh, Devanand Kumar, Sarthi Bansal, Satabdi Rautray, Manish Saini, Kshipra Jain, Reeshu Gupta, Prabuddha Kumar Kundu
Publikováno v:
Heliyon, Vol 7, Iss 10, Pp e08201- (2021)
Externí odkaz:
https://doaj.org/article/117420d8026e444fbb9e9805bd44c6ef
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006459 (2017)
Several intracellular pathogens arrest the phagosome maturation in the host cells to avoid transport to lysosomes. In contrast, the Leishmania containing parasitophorous vacuole (PV) is shown to recruit lysosomal markers and thus Leishmania is postul
Externí odkaz:
https://doaj.org/article/64a0d50fc2754f3c83a360d206220633
Autor:
Milind Jagota, Chengzhong Ye, Ruchir Rastogi, Carlos Albors, Antoine Koehl, Nilah Ioannidis, Yun S. Song
Genetic variation in the human genome is a major determinant of individual disease risk, but the vast majority of missense variants have unknown etiological effects. Various computational strategies have been proposed to predict the effects of missen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f5c9a7f35d873c98569f1afd0bed25a
https://doi.org/10.1101/2022.11.15.516532
https://doi.org/10.1101/2022.11.15.516532
Autor:
Sandhya Sen, Saswat Kumar Bal, Sameeksha Yadav, Pragya Mishra, Vishnu Vivek G, Ruchir Rastogi, Chinmay K. Mukhopadhyay
Publikováno v:
The Journal of biological chemistry. 298(12)
Iron (Fe) sequestration is one of the most important strategies of the host to control the growth and survival of invading pathogens. Ferritin (Ft) plays a pivotal role in the sequestration mechanism of mammalian hosts by storing Fe. Recent evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4daaddcd6110ea51a42f5e163adaa38
https://pubmed.ncbi.nlm.nih.gov/36309090
https://pubmed.ncbi.nlm.nih.gov/36309090
Autor:
Aelia Naqvi, Kajal Arora, Ruchir Rastogi, Jeny Paliwal, Apoorva Srivastava, Sriganesh Kalyanaraman, Deepak Parashar, Manish Saini, Prabuddha Kumar Kundu, Nupur Mehrotra Arora, Sudhir Kumar Singh, D. Kumar, Bhupesh Mali, Manglesh Kumar Singh, Vidya Bhushan Arya, Biswa Pratim, Abhishek Mukherjee, Avinash Undale, Swaroop Potdar, Saumyabrata Mazumder, Dilip Kumar, Sarthi Bansal, Aditi Gupta, Sourav Roy, Abyson Joseph, R. S. Gupta, Satabdi Rautray, Kshipra Jain
Publikováno v:
Heliyon, Vol 7, Iss 10, Pp e08201-(2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcbe2a75c7d3cfd8088883b2afa4bea
http://www.sciencedirect.com/science/article/pii/S2405844021023045
http://www.sciencedirect.com/science/article/pii/S2405844021023045