Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ruchika Srinivasan"'
Autor:
Mohamed Kabbout, Duaa Dakhlallah, Sudarshana Sharma, Agnieszka Bronisz, Ruchika Srinivasan, Melissa Piper, Clay B Marsh, Michael C Ostrowski
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100693 (2014)
The ETS-family transcription factors Ets1 and Ets2 are evolutionarily conserved effectors of the RAS/ERK signaling pathway, but their function in Ras cellular transformation and biology remains unclear. Taking advantage of Ets1 and Ets2 mouse models
Externí odkaz:
https://doaj.org/article/19cc25068df44182b59a1690d7c69575
Autor:
Ruchika Srinivasan, Tahera Zabuawala, Hong Huang, Jianying Zhang, Parul Gulati, Soledad Fernandez, J Colleen Karlo, Gary E Landreth, Gustavo Leone, Michael C Ostrowski
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8283 (2009)
Angiogenesis is a complex process orchestrated by both growth factors and cell adhesion and is initiated by focal degradation of the vascular basement membrane with subsequent migration and proliferation of endothelial cells. The Ras/Raf/MEK/ERK path
Externí odkaz:
https://doaj.org/article/97b1a14d69a348bea7eea9774b380cd7
Autor:
Michael C. Ostrowski, Gustavo Leone, Kun Huang, Soledad Fernandez, Thomas J. Rosol, Ruchika Srinivasan, Brett Adair, Anand Merchant, Sudarshana M. Sharma, David A. Taffany, Tahera Zabuawala
Supplementary Movie 1 from An Ets2-Driven Transcriptional Program in Tumor-Associated Macrophages Promotes Tumor Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10542326f6e06eeaeec8ae35e6042d20
https://doi.org/10.1158/0008-5472.22387286
https://doi.org/10.1158/0008-5472.22387286
Autor:
Michael C. Ostrowski, Gustavo Leone, Kun Huang, Soledad Fernandez, Thomas J. Rosol, Ruchika Srinivasan, Brett Adair, Anand Merchant, Sudarshana M. Sharma, David A. Taffany, Tahera Zabuawala
Supplementary Movie 3 from An Ets2-Driven Transcriptional Program in Tumor-Associated Macrophages Promotes Tumor Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79dc30bbddcfbe9ccbd7dd078f74b249
https://doi.org/10.1158/0008-5472.22387280.v1
https://doi.org/10.1158/0008-5472.22387280.v1
Autor:
Michael C. Ostrowski, Gustavo Leone, Kun Huang, Soledad Fernandez, Thomas J. Rosol, Ruchika Srinivasan, Brett Adair, Anand Merchant, Sudarshana M. Sharma, David A. Taffany, Tahera Zabuawala
Supplementary Figure and Movie Legends from An Ets2-Driven Transcriptional Program in Tumor-Associated Macrophages Promotes Tumor Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629d8009fde8c2ae5d38e59caf1da82a
https://doi.org/10.1158/0008-5472.22387292.v1
https://doi.org/10.1158/0008-5472.22387292.v1
Autor:
Michael C. Ostrowski, Gustavo Leone, Kun Huang, Soledad Fernandez, Thomas J. Rosol, Ruchika Srinivasan, Brett Adair, Anand Merchant, Sudarshana M. Sharma, David A. Taffany, Tahera Zabuawala
Supplementary Figures 1-7 from An Ets2-Driven Transcriptional Program in Tumor-Associated Macrophages Promotes Tumor Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20672001fd02b4e3e96d06487a7f8bb5
https://doi.org/10.1158/0008-5472.22387289
https://doi.org/10.1158/0008-5472.22387289
Autor:
Gustavo Leone, Thomas J. Rosol, Sudarshana M. Sharma, Soledad Fernandez, Kun Huang, Tahera Zabuawala, Brett Adair, Ruchika Srinivasan, Michael C. Ostrowski, Anand S. Merchant, David A. Taffany
Publikováno v:
Cancer Research. 70:1323-1333
Tumor-associated macrophages (TAM) are implicated in breast cancer metastasis, but relatively little is known about the underlying genes and pathways that are involved. The transcription factor Ets2 is a direct target of signaling pathways involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d6b2b15182463a59c05f66c52a4632
https://doi.org/10.1158/0008-5472.can-09-1474
https://doi.org/10.1158/0008-5472.can-09-1474
Autor:
Michael C. Ostrowski, Agnieszka Bronisz, Uma Sankar, Rong Hu, Sudarshana M. Sharma, Ruchika Srinivasan
Publikováno v:
Molecular and Cellular Biology. 27:4018-4027
Transcription factors MITF and PU.1 collaborate to increase expression of target genes like cathepsin K (Ctsk) and acid phosphatase 5 (Acp5) during osteoclast differentiation. We show that these factors can also repress transcription of target genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce21c93287422aa3f2f6b551f851e98f
https://doi.org/10.1128/mcb.01839-06
https://doi.org/10.1128/mcb.01839-06
Autor:
Gustavo Leone, Jianying Zhang, Michael C. Ostrowski, Parul Gulati, Soledad Fernandez, Hong Huang, Tahera Zabuawala, Gary E. Landreth, Ruchika Srinivasan, J. Colleen Karlo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 12, p e8283 (2009)
PLoS ONE, Vol 4, Iss 12, p e8283 (2009)
Angiogenesis is a complex process orchestrated by both growth factors and cell adhesion and is initiated by focal degradation of the vascular basement membrane with subsequent migration and proliferation of endothelial cells. The Ras/Raf/MEK/ERK path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3c7f62ca18cec80783c3bc1b85b983
https://pubmed.ncbi.nlm.nih.gov/20011539
https://pubmed.ncbi.nlm.nih.gov/20011539
Autor:
Michael H. Weinstein, Guo Wei, Natarajan Muthusamy, Michael C. Ostrowski, Ruchika Srinivasan, Carmen Z. Cantemir-Stone, Albert K. Man, Gustavo Leone, Sudarshana M. Sharma, Ramasamy Santhanam, Robert G. Oshima
Publikováno v:
Blood. 114(5)
The ras/Raf/Mek/Erk pathway plays a central role in coordinating endothelial cell activities during angiogenesis. Transcription factors Ets1 and Ets2 are targets of ras/Erk signaling pathways that have been implicated in endothelial cell function in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f696a6d4464592f82fdb46b793e131d2
https://pubmed.ncbi.nlm.nih.gov/19643995
https://pubmed.ncbi.nlm.nih.gov/19643995