Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ruchika Nijhara"'
Autor:
Ashok B. Kulkarni, Howard Jaffe, J. Silvio Gutkind, Ya-Li Zheng, Sashi Kesavapany, Harish C. Pant, Satoru Takahashi, Ruchika Nijhara, Ram K. Sihag, Niranjana D. Amin, Philip Grant
Publikováno v:
The Journal of Neuroscience. 24:4421-4431
Cyclin-dependent kinase 5 (Cdk5) is a proline-directed kinase the activity of which is dependent on association with its neuron-specific activators, p35 and p39. Cdk5 activity is critical for the proper formation of cortical structures and lamination
Autor:
Ruchika Nijhara, Stanley L. Erlandsen, Martin J. Brown, Stephen Shaw, John A. Hallam, Jérôme Delon, Kenneth M. Yamada, Michelle Gignac, Michael J. Kruhlak
Publikováno v:
Blood. 102:3890-3899
Lymphocyte microvilli mediate initial rolling-adhesion along endothelium but are lost during transmigration from circulation to tissue. However, the mechanism for resorption of lymphocyte microvilli remains unexplored. We show that chemokine stimulat
Publikováno v:
FEBS Letters. 504:59-64
The human hepatitis B virus X protein (HBx) is known as a dual-specificity transactivator stimulating the transcriptional machinery in the nucleus and signal transduction pathways in the cytoplasm. HBx-induced activation of mitogen-activated protein
Autor:
Krishna Balakrishnan, Ruchika Nijhara
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 2(2)
Scientists and entrepreneurs who contemplate developing nanomedicine products face several unique challenges in addition to many of the traditional hurdles of product development. In this review we analyze the major physicochemical, biologic and func
Autor:
Stephen Shaw, Paula B. van Hennik, Jérôme Delon, Peter L. Hordijk, Michelle Gignac, Michael J. Kruhlak, Ruchika Nijhara
Publikováno v:
Journal of Immunology, 173(8), 4985-4993. American Association of Immunologists
Journal of immunology (Baltimore, Md., 173(8), 4985-4993. American Association of Immunologists
Nijhara, R, Van Hennik, P B, Gignac, M L, Kruhlak, M J, Hordijk, P L, Delon, J & Shaw, S 2004, ' Rac1 mediates collapse of microvilli on chemokine-activated T lymphocytes ', Journal of Immunology, vol. 173, no. 8, pp. 4985-4993 . https://doi.org/10.4049/jimmunol.173.8.4985
Journal of immunology (Baltimore, Md., 173(8), 4985-4993. American Association of Immunologists
Nijhara, R, Van Hennik, P B, Gignac, M L, Kruhlak, M J, Hordijk, P L, Delon, J & Shaw, S 2004, ' Rac1 mediates collapse of microvilli on chemokine-activated T lymphocytes ', Journal of Immunology, vol. 173, no. 8, pp. 4985-4993 . https://doi.org/10.4049/jimmunol.173.8.4985
Lymphocytes circulate in the blood and upon chemokine activation rapidly bind, where needed, to microvasculature to mediate immune surveillance. Resorption of microvilli is an early morphological alteration induced by chemokines that facilitates lymp
Autor:
Shyamal K. Goswami, Debi P. Sarkar, Subeer S. Majumdar, Siddhartha S. Jana, Ruchika Nijhara, Ajay Rana, Vijay Kumar
Publikováno v:
Journal of virology. 75(21)
Transcriptional activation of diverse cellular genes by the X protein (HBx) of hepatitis B virus (HBV) has been suggested as one of the mechanisms for HBV-associated hepatocellular carcinoma. However, such functions of HBx have been studied using tra