Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rucha D Sarwade"'
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194482 (2018)
Understanding the regulation of insulin biosynthesis is important as it plays a central role in glucose metabolism. The mouse insulin gene2 (Ins2) has two splice variants; long (Ins2L) and short (Ins2S), that differ only in their 5'UTR sequence and I
Externí odkaz:
https://doaj.org/article/b5c7617d56834b1cbbbd651d8469bfd4
Autor:
Vasudevan Seshadri, Rucha D. Sarwade, Shardul D. Kulkarni, Abdul Khalique, Naina Gaikwad, Poonam R. Pandey
Publikováno v:
Biochemical and Biophysical Research Communications. 526:618-625
Glucose mediated insulin biosynthesis is tightly regulated and shared between insulin granule proteins such as its processing enzymes, prohormone convertases, PC1/3 and PC2. However, the molecular players involved in the co-ordinated translation rema
Autor:
Vasudevan Seshadri, Poonam R. Pandey, Abdul Khalique, Rucha D. Sarwade, Maleppillil Vavachan Vijayakumar, Manoj Kumar Bhat
Publikováno v:
Biochemical and Biophysical Research Communications. 474:64-70
Insulin maintains glucose homeostasis by stimulating glucose uptake from extracellular environment to adipose and muscle tissue through glucose transporter (GLUT4). Insulin resistance plays a significant role in pathologies associated with type2 diab
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Frontiers in Endocrinology
Frontiers in Endocrinology
Type 2 diabetes mellitus (T2DM) is no more a lifestyle disease of developed countries. It has emerged as a major health problem worldwide including developing countries. However, how diabetes could be detected at an early stage (prediabetes) to preve
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0194482 (2018)
PLoS ONE, Vol 13, Iss 3, p e0194482 (2018)
Understanding the regulation of insulin biosynthesis is important as it plays a central role in glucose metabolism. The mouse insulin gene2 (Ins2) has two splice variants; long (Ins2L) and short (Ins2S), that differ only in their 5'UTR sequence and I
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Type 2 diabetes mellitus (T2DM) is no more a lifestyle disease of developed countries. It has emerged as a major health problem worldwide including developing countries. However, how diabetes could be detected at an early stage (prediabetes) to preve
Externí odkaz:
https://doaj.org/article/d8894b345c644576a38225157d9bfabc