Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Ruby Yun‐Ju Huang"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Epithelial-mesenchymal transition (EMT) is a dynamic process enabling polarized epithelial cells to acquire mesenchymal features implicated in development and carcinoma progression. As our understanding evolves, it is clear the reversible ex
Externí odkaz:
https://doaj.org/article/abbf2eacf6314d1dbfa0dd040f927430
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 4, Pp n/a-n/a (2024)
Abstract Gastric poorly cohesive carcinoma (PCC) manifests with a diffuse pattern and diverse tumor cell morphologies, often indicating a more unfavorable prognosis. Recent consensus has reclassified PCC based on the proportion of signet‐ring cells
Externí odkaz:
https://doaj.org/article/1a58e37629db423f918ea3f73c647efb
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 56, Iss 4, Pp 729-738 (2023)
Background: Reactive lymphadenopathies such as toxoplasmosis and cytomegalovirus lymphadenitis are associated with monocytoid cell proliferation. Monocytoid cells are B-lymphocytes with an undetermined subset. Methods: Using digital spatial profiling
Externí odkaz:
https://doaj.org/article/bba1dc1fb86d4ae99502d5699b0d9be7
Autor:
Xun Hui Yeo, Vignesh Sundararajan, Zhengwei Wu, Zi Jin Cheryl Phua, Yin Ying Ho, Kai Lay Esther Peh, Yi-Chia Chiu, Tuan Zea Tan, Dennis Kappei, Ying Swan Ho, David Shao Peng Tan, Wai Leong Tam, Ruby Yun-Ju Huang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-6 (2023)
Externí odkaz:
https://doaj.org/article/4669c9aed0f141f9b131ea498542c898
Autor:
Xun Hui Yeo, Vignesh Sundararajan, Zhengwei Wu, Zi Jin Cheryl Phua, Yin Ying Ho, Kai Lay Esther Peh, Yi-Chia Chiu, Tuan Zea Tan, Dennis Kappei, Ying Swan Ho, David Shao Peng Tan, Wai Leong Tam, Ruby Yun-Ju Huang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract AXL is a receptor tyrosine kinase that is often overexpressed in cancers. It contributes to pathophysiology in cancer progression and therapeutic resistance, making it an emerging therapeutic target. The first-in-class AXL inhibitor bemcenti
Externí odkaz:
https://doaj.org/article/e4c51514b6d442e4b1c53e454bfbf0d3
Autor:
Qing You Pang, Tuan Zea Tan, Vignesh Sundararajan, Yi-Chia Chiu, Edward Yu Wing Chee, Vin Yee Chung, Mahesh A. Choolani, Ruby Yun-Ju Huang
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-31 (2022)
Abstract Background The plasticity along the epithelial-mesenchymal transition (EMT) spectrum has been shown to be regulated by various epigenetic repertoires. Emerging evidence of local chromatin conformation changes suggests that regulation of EMT
Externí odkaz:
https://doaj.org/article/724cb006a5314591b4fd1dcd91a52103
Autor:
Ser Yue Loo, Nicholas L. Syn, Angele Pei-Fern Koh, Janet Cheng-Fei Teng, Amudha Deivasigamani, Tuan Zea Tan, Aye Aye Thike, Shireen Vali, Shweta Kapoor, Xiaoyuan Wang, Jiong Wei Wang, Puay Hoon Tan, George W. Yip, Gautam Sethi, Ruby Yun-Ju Huang, Kam Man Hui, Lingzhi Wang, Boon Cher Goh, Alan Prem Kumar
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract Clinical trials repurposing peroxisome proliferator-activated receptor-gamma (PPARγ) agonists as anticancer agents have exhibited lackluster efficacy across a variety of tumor types. Here, we report that increased PPARG expression is associ
Externí odkaz:
https://doaj.org/article/82fb2ea92fce4d45b46ee3f019c45a37
Autor:
Ching-Hung Lin, Ruby Yun-Ju Huang, Tzu-Pin Lu, Kuan-Ting Kuo, Ko-Yun Lo, Ching-Hsuan Chen, I-Chun Chen, Yen-Shen Lu, Eric Y. Chuang, Jean Paul Thiery, Chiun-Sheng Huang, Ann-Lii Cheng
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract In East Asia, the breast cancer incidence rate among women aged
Externí odkaz:
https://doaj.org/article/639f57b5e1b448d0bef6e0021dda94f1
Autor:
Tuan Zea Tan, Jieru Ye, Chung Vin Yee, Diana Lim, Natalie Yan Li Ngoi, David Shao Peng Tan, Ruby Yun-Ju Huang
Publikováno v:
EBioMedicine, Vol 50, Iss , Pp 203-210 (2019)
Background: Ovarian clear cell carcinoma (OCCC) is a histological subtype of epithelial ovarian cancer (EOC) with distinct pathological, biological, and molecular features. OCCCs are more resistant to conventional treatment regimen of EOC and have th
Externí odkaz:
https://doaj.org/article/a7dd807f3dde4c84939199d56484b1f8
Autor:
Ming Tan, Mohammad Asad, Valerie Heong, Meng Kang Wong, Tuan Zea Tan, Jieru Ye, Kuee Theng Kuay, Jean Paul Thiery, Clare Scott, Ruby Yun‐Ju Huang
Publikováno v:
Molecular Oncology, Vol 13, Iss 4, Pp 757-780 (2019)
Frizzled family receptor 7 (FZD7), a Wnt signaling receptor, is associated with the maintenance of stem cell properties and cancer progression. FZD7 has emerged as a potential therapeutic target because it is capable of transducing both canonical and
Externí odkaz:
https://doaj.org/article/627ec59c33f042d7ac79b4f714ad778a